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NPM3 (nucleophosmin/nucleoplasmin 3)

Identity

Other aliasPORMIN
TMEM123
HGNC (Hugo) NPM3
LocusID (NCBI) 10360
Atlas_Id 70946
Location 10q24.32  [Link to chromosome band 10q24]
Location_base_pair Starts at 101781325 and ends at 101783413 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NPM3   7931
Cards
Entrez_Gene (NCBI)NPM3  10360  nucleophosmin/nucleoplasmin 3
AliasesPORMIN; TMEM123
GeneCards (Weizmann)NPM3
Ensembl hg19 (Hinxton)ENSG00000107833 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000107833 [Gene_View]  chr10:101781325-101783413 [Contig_View]  NPM3 [Vega]
ICGC DataPortalENSG00000107833
TCGA cBioPortalNPM3
AceView (NCBI)NPM3
Genatlas (Paris)NPM3
WikiGenes10360
SOURCE (Princeton)NPM3
Genetics Home Reference (NIH)NPM3
Genomic and cartography
GoldenPath hg38 (UCSC)NPM3  -     chr10:101781325-101783413 -  10q24.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NPM3  -     10q24.32   [Description]    (hg19-Feb_2009)
EnsemblNPM3 - 10q24.32 [CytoView hg19]  NPM3 - 10q24.32 [CytoView hg38]
Mapping of homologs : NCBINPM3 [Mapview hg19]  NPM3 [Mapview hg38]
OMIM606456   
Gene and transcription
Genbank (Entrez)AF081280 AY049737 BC041067 BC054868 BM739536
RefSeq transcript (Entrez)NM_006993
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NPM3
Cluster EST : UnigeneHs.90691 [ NCBI ]
CGAP (NCI)Hs.90691
Alternative Splicing GalleryENSG00000107833
Gene ExpressionNPM3 [ NCBI-GEO ]   NPM3 [ EBI - ARRAY_EXPRESS ]   NPM3 [ SEEK ]   NPM3 [ MEM ]
Gene Expression Viewer (FireBrowse)NPM3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10360
GTEX Portal (Tissue expression)NPM3
Human Protein AtlasENSG00000107833-NPM3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75607   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75607  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75607
Splice isoforms : SwissVarO75607
PhosPhoSitePlusO75607
Domains : Interpro (EBI)Nucleoplasmin    Nucleoplasmin_core_dom   
Domain families : Pfam (Sanger)Nucleoplasmin (PF03066)   
Domain families : Pfam (NCBI)pfam03066   
Conserved Domain (NCBI)NPM3
DMDM Disease mutations10360
Blocks (Seattle)NPM3
SuperfamilyO75607
Human Protein Atlas [tissue]ENSG00000107833-NPM3 [tissue]
Peptide AtlasO75607
HPRD07346
IPIIPI00026496   
Protein Interaction databases
DIP (DOE-UCLA)O75607
IntAct (EBI)O75607
FunCoupENSG00000107833
BioGRIDNPM3
STRING (EMBL)NPM3
ZODIACNPM3
Ontologies - Pathways
QuickGOO75607
Ontology : AmiGORNA binding  protein binding  nucleolus  cytosol  rRNA processing  rRNA transcription  actin cytoskeleton  
Ontology : EGO-EBIRNA binding  protein binding  nucleolus  cytosol  rRNA processing  rRNA transcription  actin cytoskeleton  
NDEx NetworkNPM3
Atlas of Cancer Signalling NetworkNPM3
Wikipedia pathwaysNPM3
Orthology - Evolution
OrthoDB10360
GeneTree (enSembl)ENSG00000107833
Phylogenetic Trees/Animal Genes : TreeFamNPM3
HOVERGENO75607
HOGENOMO75607
Homologs : HomoloGeneNPM3
Homology/Alignments : Family Browser (UCSC)NPM3
Gene fusions - Rearrangements
Fusion: Tumor Portal NPM3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNPM3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NPM3
dbVarNPM3
ClinVarNPM3
1000_GenomesNPM3 
Exome Variant ServerNPM3
ExAC (Exome Aggregation Consortium)ENSG00000107833
GNOMAD BrowserENSG00000107833
Genetic variants : HAPMAP10360
Genomic Variants (DGV)NPM3 [DGVbeta]
DECIPHERNPM3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNPM3 
Mutations
ICGC Data PortalNPM3 
TCGA Data PortalNPM3 
Broad Tumor PortalNPM3
OASIS PortalNPM3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNPM3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNPM3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NPM3
DgiDB (Drug Gene Interaction Database)NPM3
DoCM (Curated mutations)NPM3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NPM3 (select a term)
intoGenNPM3
Cancer3DNPM3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606456   
Orphanet
MedgenNPM3
Genetic Testing Registry NPM3
NextProtO75607 [Medical]
TSGene10360
GENETestsNPM3
Target ValidationNPM3
Huge Navigator NPM3 [HugePedia]
snp3D : Map Gene to Disease10360
BioCentury BCIQNPM3
ClinGenNPM3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10360
Chemical/Pharm GKB GenePA31733
Clinical trialNPM3
Miscellaneous
canSAR (ICR)NPM3 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNPM3
EVEXNPM3
GoPubMedNPM3
iHOPNPM3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:19:20 CET 2017

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