NPS (neuropeptide S)

2014-11-01  

Identity

HGNC
LOCATION
10q26.2
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 594857
MIM: 609513
HGNC: 33940
Ensembl: ENSG00000214285

Variants:

dbSNP: 594857
ClinVar: 594857
TCGA: ENSG00000214285
COSMIC: NPS

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000214285ENST00000398023P0C0P6

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (s) signalling eventsREACTOMER-HSA-418555
G alpha (q) signalling eventsREACTOMER-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPKREACTOMER-HSA-881907

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.75
204053302011Non-synonymous polymorphism in the neuropeptide S precursor gene and sleep apnea.2
165747942006Neuropeptide S stimulates the hypothalamo-pituitary-adrenal axis and inhibits food intake.0
167205712006Structure-activity studies on neuropeptide S: identification of the amino acid residues crucial for receptor activation.0
167904402006Structure-function relationships in the neuropeptide S receptor: molecular consequences of the asthma-associated mutation N107I.0
169261872006Downstream target genes of the neuropeptide S-NPSR1 pathway.0
183764182008Neuropeptide S is a stimulatory anxiolytic agent: a behavioural study in mice.0
198240512010Neurobiology, pharmacology, and medicinal chemistry of neuropeptide S and its receptor.0
207051472010Assessment of the neuropeptide S system in anxiety disorders.0
207051472010Assessment of the neuropeptide S system in anxiety disorders.0

Citation

Dessen P

NPS (neuropeptide S)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70950/nps