NPSR1 (neuropeptide S receptor 1)

2014-11-01 Affiliation

Identity

HGNC

NPSR1

LOCATION

7p14.3

LOCUSID

387129

ALIAS

ASRT2,GPR154,GPRA,NPSR,PGR14,VRR1

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 387129
MIM: 608595
HGNC: 23631
Ensembl: ENSG00000187258

Variants:

dbSNP: 387129
ClinVar: 387129
TCGA: ENSG00000187258
COSMIC: NPSR1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000187258	ENST00000359791	Q6W5P4
ENSG00000187258	ENST00000360581	Q6W5P4
ENSG00000187258	ENST00000360581	A0A090N8Z1
ENSG00000187258	ENST00000381539	Q6W5P4
ENSG00000187258	ENST00000381542	Q6W5P4
ENSG00000187258	ENST00000381544	Q6W5P4
ENSG00000187258	ENST00000381553	Q6W5P4
ENSG00000187258	ENST00000396095	Q6W5P4
ENSG00000187258	ENST00000465305	Q6W5P4
ENSG00000187258	ENST00000531252	Q6W5P4

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Signal Transduction	REACTOME	R-HSA-162582
Signaling by GPCR	REACTOME	R-HSA-372790
GPCR ligand binding	REACTOME	R-HSA-500792
Class A/1 (Rhodopsin-like receptors)	REACTOME	R-HSA-373076
Peptide ligand-binding receptors	REACTOME	R-HSA-375276
GPCR downstream signaling	REACTOME	R-HSA-388396
G alpha (s) signalling events	REACTOME	R-HSA-418555
G alpha (q) signalling events	REACTOME	R-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPK	REACTOME	R-HSA-881907

References

Pubmed ID	Year	Title	Citations
17703412	2007	Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.	100
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	85
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	62
19247692	2009	Analyses of associations with asthma in four asthma population samples from Canada and Australia.	39
19264973	2009	Assessing the reproducibility of asthma candidate gene associations, using genome-wide data.	36
18588753	2008	Epithelial genes in chronic rhinosinusitis with and without nasal polyps.	34
17702965	2007	Comprehensive testing of positionally cloned asthma genes in two populations.	32
17702965	2007	Comprehensive testing of positionally cloned asthma genes in two populations.	32
19258923	2009	Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.	26
20503287	2010	Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.	17

Citation

Dessen P

NPSR1 (neuropeptide S receptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/54945/npsr1