NPY5R (neuropeptide Y receptor Y5)

2010-08-01  

Identity

HGNC
LOCATION
4q32.2
LOCUSID
ALIAS
NPY5-R,NPYR5,NPYY5-R

Other Information

Locus ID:

NCBI: 4889
MIM: 602001
HGNC: 7958
Ensembl: ENSG00000164129

Variants:

dbSNP: 4889
ClinVar: 4889
TCGA: ENSG00000164129
COSMIC: NPY5R

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164129ENST00000338566Q15761
ENSG00000164129ENST00000506953Q15761
ENSG00000164129ENST00000515560Q15761

Expression (GTEx)

0
1
2
3
4
5
6

Pathways

PathwaySourceExternal ID
Neuroactive ligand-receptor interactionKEGGko04080
Neuroactive ligand-receptor interactionKEGGhsa04080
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

References

Pubmed IDYearTitleCitations
198745742009Genetical genomic determinants of alcohol consumption in rats and humans.93
168916222006Neuropeptide Y induces migration, proliferation, and tube formation of endothelial cells bimodally via Y1, Y2, and Y5 receptors.40
188288112008Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence.34
188288112008Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence.34
190860532009Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.34
204680642010Association study of 182 candidate genes in anorexia nervosa.30
239004452014Genetic association analysis of 30 genes related to obesity in a European American population.26
190587892009A common variant in DRD3 receptor is associated with autism spectrum disorder.19
195932122009Novel genetic variants contributing to left ventricular hypertrophy: the HyperGEN study.17
173252592007Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: a possible role for NPY2R as a candidate gene for type 2 diabetes in men.15

Citation

Dessen P

NPY5R (neuropeptide Y receptor Y5)

Atlas Genet Cytogenet Oncol Haematol. 2010-08-01

Online version: http://atlasgeneticsoncology.org/gene/51584/npy5r