| Nomenclature | | HGNC (Hugo) | NR0B1 7960 |
| Entrez_Gene (NCBI) | NR0B1 190 nuclear receptor subfamily 0, group B, member 1 |
| Cards | | GeneCards (Weizmann) | NR0B1 |
| Ensembl (Hinxton) | ENSG00000169297 [Gene_View] chrX:30322539-30327495 [Contig_View] NR0B1 [Vega] |
| AceView (NCBI) | NR0B1 |
| Genatlas (Paris) | NR0B1 |
| SOURCE (Stanford) | NM_000475 |
| Genomic and cartography | | GoldenPath (UCSC) | NR0B1 - Xp21.2 chrX:30322539-30327495 - Xp21.2 [Description] (hg19-Feb_2009) |
| Ensembl | NR0B1 - Xp21.2 [CytoView] |
| Mapping of homologs : NCBI | NR0B1 [Mapview] |
| OMIM | 300018 300200 300473 |
| Gene and transcription |
| Genbank (Entrez) | AW612655 BC011564 BI772108 HQ692832 S74720 |
| RefSeq transcript (SRS) | NM_000475 |
| RefSeq transcript (Entrez) | NM_000475 |
| RefSeq genomic (SRS) | AC_000155 NC_000023 NC_018934 NG_009814 NT_167197 NW_001842360 NW_004078118 |
| RefSeq genomic (Entrez) | AC_000155 NC_000023 NC_018934 NG_009814 NT_167197 NW_001842360 NW_004078118 |
| Consensus coding sequences : CCDS (NCBI) | NR0B1 |
| Cluster EST : Unigene | Hs.268490 [ SRS ] Hs.268490 [ NCBI ] |
| CGAP (NCI) | Hs.268490 |
| Alternative Splicing : Fast-db (Paris) | GSHG0032026 |
| Alternative Splicing Gallery | ENSG00000169297 |
| Gene Expression | NR0B1 [ NCBI-GEO ] NR0B1 [ EBI - ARRAY_EXPRESS ] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P51843 (SRS) P51843 (Uniprot) |
| NextProt | P51843 |
| With graphics : InterPro | P51843 |
| Splice isoforms : SwissVar | P51843(Swissvar) |
| Domains : Interpro (SRS) | Nucl_hormone_rcpt_ligand-bd Nucl_hrmn_rcpt_lig-bd_core Nuclear_receptor_repeat Str_hrmn_rcpt |
| Domains : Interpro (EBI) | Nucl_hormone_rcpt_ligand-bd Nucl_hrmn_rcpt_lig-bd_core Nuclear_receptor_repeat Str_hrmn_rcpt |
| Related proteins : CluSTr | P51843 |
| Domain families : Pfam (SRS) | Hormone_recep (PF00104) NR_Repeat (PF14046) |
| Domain families : Pfam (Sanger) | Hormone_recep (PF00104) NR_Repeat (PF14046) |
| Domain families : Pfam (NCBI) | pfam00104 pfam14046 |
| Domain families : Smart (EMBL) | HOLI (SM00430) |
| DMDM | 190 |
| Blocks (Seattle) | P51843 |
| Human Protein Atlas | ENSG00000169297 |
| HPRD | 08362 |
| IPI | IPI00020943 IPI00646717 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P51843 |
| IntAct (EBI) | P51843 |
| FunCoup | ENSG00000169297 |
| REACTOME | NR0B1 |
| Protein Interaction Database | 190 |
| BioGRID | NR0B1 |
| InParanoid | P51843 |
| Interologous Interaction database | P51843 |
| IntegromeDB | NR0B1 |
| Polymorphism : SNP, mutations, diseases | | SNP Single Nucleotide Polymorphism (NCBI) | NR0B1 |
| SNP (GeneSNP Utah) | NR0B1 |
| SNP : HGBase | NR0B1 |
| Genetic variants : HAPMAP | NR0B1 |
| Somatic Mutations in Cancer : COSMIC | NR0B1 |
| CONAN: Copy Number Analysis | NR0B1 |
| Mutations and Diseases : HGMD | NR0B1 |
| OMIM | 300018 300200 300473 |
| GENETests | 300018 300200 300473 |
| Disease Genetic Association | NR0B1 |
| Huge Navigator |
NR0B1 [HugePedia] NR0B1 [HugeCancerGEM] |
| Genomic Variants | NR0B1 NR0B1 [DGVbeta] |
| snp3D : Map Gene to Disease | 190 |
| General knowledge |
|---|
| Homologs : HomoloGene | NR0B1 |
| Homology/Alignments : Family Browser (UCSC) | NR0B1 |
| Phylogenetic Trees/Animal Genes : TreeFam | NR0B1 |
| Chemical/Protein Interactions : CTD | 190 |
| Chemical/Pharm GKB Gene | PA31746 |
| Clinical trial | NR0B1 |
| Cancer Resource (Charite) | ENSG00000169297 |
| Ontology : AmiGO | negative regulation of transcription from RNA polymerase II promoter DNA binding double-stranded DNA binding steroid hormone receptor activity transcription corepressor activity RNA binding ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity protein binding nucleus nucleoplasm cytoplasm transcription initiation from RNA polymerase II promoter steroid biosynthetic process response to stress spermatogenesis protein localization transcription factor binding gonad development male gonad development gene expression membrane protein domain specific binding hypothalamus development pituitary gland development male sex determination adrenal gland development intracellular receptor mediated signaling pathway intracellular receptor mediated signaling pathway DNA hairpin binding negative regulation of intracellular steroid hormone receptor signaling pathway Leydig cell differentiation steroid hormone receptor binding polysomal ribosome protein homodimerization activity negative regulation of sequence-specific DNA binding transcription factor activity response to peptide hormone stimulus sequence-specific DNA binding negative regulation of cell differentiation negative regulation of transcription, DNA-dependent negative regulation of transcription, DNA-dependent AF-2 domain binding Sertoli cell differentiation |
| Ontology : EGO-EBI | negative regulation of transcription from RNA polymerase II promoter DNA binding double-stranded DNA binding steroid hormone receptor activity transcription corepressor activity RNA binding ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity protein binding nucleus nucleoplasm cytoplasm transcription initiation from RNA polymerase II promoter steroid biosynthetic process response to stress spermatogenesis protein localization transcription factor binding gonad development male gonad development gene expression membrane protein domain specific binding hypothalamus development pituitary gland development male sex determination adrenal gland development intracellular receptor mediated signaling pathway intracellular receptor mediated signaling pathway DNA hairpin binding negative regulation of intracellular steroid hormone receptor signaling pathway Leydig cell differentiation steroid hormone receptor binding polysomal ribosome protein homodimerization activity negative regulation of sequence-specific DNA binding transcription factor activity response to peptide hormone stimulus sequence-specific DNA binding negative regulation of cell differentiation negative regulation of transcription, DNA-dependent negative regulation of transcription, DNA-dependent AF-2 domain binding Sertoli cell differentiation |
| Pathways : BIOCARTA | CARM1 and Regulation of the Estrogen Receptor [Genes] |
| Other databases |
| Probes |
|---|
| Litterature | | PubMed | 118 Pubmed reference(s) in Entrez |
| PubGene | NR0B1 |
| iHOP | NR0B1 |
