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NR1I3 (nuclear receptor subfamily 1 group I member 3)

Identity

Alias_namesnuclear receptor subfamily 1
Alias_symbol (synonym)MB67
CAR1
CAR
Other alias
HGNC (Hugo) NR1I3
LocusID (NCBI) 9970
Atlas_Id 46293
Location 1q23.3  [Link to chromosome band 1q23]
Location_base_pair Starts at 161199456 and ends at 161208000 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NR1I3   7969
Cards
Entrez_Gene (NCBI)NR1I3  9970  nuclear receptor subfamily 1 group I member 3
AliasesCAR; CAR1; MB67
GeneCards (Weizmann)NR1I3
Ensembl hg19 (Hinxton)ENSG00000143257 [Gene_View]  chr1:161199456-161208000 [Contig_View]  NR1I3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000143257 [Gene_View]  chr1:161199456-161208000 [Contig_View]  NR1I3 [Vega]
ICGC DataPortalENSG00000143257
TCGA cBioPortalNR1I3
AceView (NCBI)NR1I3
Genatlas (Paris)NR1I3
WikiGenes9970
SOURCE (Princeton)NR1I3
Genetics Home Reference (NIH)NR1I3
Genomic and cartography
GoldenPath hg19 (UCSC)NR1I3  -     chr1:161199456-161208000 -  1q23.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NR1I3  -     1q23.3   [Description]    (hg38-Dec_2013)
EnsemblNR1I3 - 1q23.3 [CytoView hg19]  NR1I3 - 1q23.3 [CytoView hg38]
Mapping of homologs : NCBINR1I3 [Mapview hg19]  NR1I3 [Mapview hg38]
OMIM603881   
Gene and transcription
Genbank (Entrez)AA918394 AB307702 AK303757 AK303796 AK310773
RefSeq transcript (Entrez)NM_001077469 NM_001077470 NM_001077471 NM_001077472 NM_001077473 NM_001077474 NM_001077475 NM_001077476 NM_001077477 NM_001077478 NM_001077479 NM_001077480 NM_001077481 NM_001077482 NM_005122
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_029113 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)NR1I3
Cluster EST : UnigeneHs.349642 [ NCBI ]
CGAP (NCI)Hs.349642
Alternative Splicing GalleryENSG00000143257
Gene ExpressionNR1I3 [ NCBI-GEO ]   NR1I3 [ EBI - ARRAY_EXPRESS ]   NR1I3 [ SEEK ]   NR1I3 [ MEM ]
Gene Expression Viewer (FireBrowse)NR1I3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9970
GTEX Portal (Tissue expression)NR1I3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14994   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14994  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14994
Splice isoforms : SwissVarQ14994
PhosPhoSitePlusQ14994
Domaine pattern : Prosite (Expaxy)NUCLEAR_REC_DBD_1 (PS00031)    NUCLEAR_REC_DBD_2 (PS51030)   
Domains : Interpro (EBI)Nucl_hrmn_rcpt_lig-bd    Nuclear_hrmn_rcpt    ThyrH_rcpt    Znf_hrmn_rcpt    Znf_NHR/GATA   
Domain families : Pfam (Sanger)Hormone_recep (PF00104)    zf-C4 (PF00105)   
Domain families : Pfam (NCBI)pfam00104    pfam00105   
Domain families : Smart (EMBL)HOLI (SM00430)  ZnF_C4 (SM00399)  
Conserved Domain (NCBI)NR1I3
DMDM Disease mutations9970
Blocks (Seattle)NR1I3
PDB (SRS)1XV9    1XVP   
PDB (PDBSum)1XV9    1XVP   
PDB (IMB)1XV9    1XVP   
PDB (RSDB)1XV9    1XVP   
Structural Biology KnowledgeBase1XV9    1XVP   
SCOP (Structural Classification of Proteins)1XV9    1XVP   
CATH (Classification of proteins structures)1XV9    1XVP   
SuperfamilyQ14994
Human Protein AtlasENSG00000143257
Peptide AtlasQ14994
HPRD04858
IPIIPI00418379   IPI00001687   IPI00816296   IPI00434588   IPI00434601   IPI00966887   IPI00967024   IPI00929633   IPI00815785   IPI00434598   IPI00967484   IPI00816473   IPI00816486   IPI00434584   IPI00434592   IPI00815775   IPI00434579   IPI00966188   IPI00434589   IPI00815841   IPI00815906   IPI00816112   IPI00816422   IPI00816193   IPI00816695   IPI00816828   
Protein Interaction databases
DIP (DOE-UCLA)Q14994
IntAct (EBI)Q14994
FunCoupENSG00000143257
BioGRIDNR1I3
STRING (EMBL)NR1I3
ZODIACNR1I3
Ontologies - Pathways
QuickGOQ14994
Ontology : AmiGORNA polymerase II regulatory region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  osteoblast differentiation  DNA binding  transcription factor activity, sequence-specific DNA binding  transcription coactivator activity  RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding  androgen receptor activity  thyroid hormone receptor activity  nucleus  nucleoplasm  nucleoplasm  cytoplasm  cytosol  cytoskeleton  transcription initiation from RNA polymerase II promoter  signal transduction  zinc ion binding  androgen receptor signaling pathway  intracellular receptor signaling pathway  negative regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  
Ontology : EGO-EBIRNA polymerase II regulatory region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  osteoblast differentiation  DNA binding  transcription factor activity, sequence-specific DNA binding  transcription coactivator activity  RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding  androgen receptor activity  thyroid hormone receptor activity  nucleus  nucleoplasm  nucleoplasm  cytoplasm  cytosol  cytoskeleton  transcription initiation from RNA polymerase II promoter  signal transduction  zinc ion binding  androgen receptor signaling pathway  intracellular receptor signaling pathway  negative regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  
Pathways : BIOCARTANuclear Receptors in Lipid Metabolism and Toxicity [Genes]    Mechanism of Acetaminophen Activity and Toxicity [Genes]   
NDEx NetworkNR1I3
Atlas of Cancer Signalling NetworkNR1I3
Wikipedia pathwaysNR1I3
Orthology - Evolution
OrthoDB9970
GeneTree (enSembl)ENSG00000143257
Phylogenetic Trees/Animal Genes : TreeFamNR1I3
HOVERGENQ14994
HOGENOMQ14994
Homologs : HomoloGeneNR1I3
Homology/Alignments : Family Browser (UCSC)NR1I3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNR1I3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NR1I3
dbVarNR1I3
ClinVarNR1I3
1000_GenomesNR1I3 
Exome Variant ServerNR1I3
ExAC (Exome Aggregation Consortium)NR1I3 (select the gene name)
Genetic variants : HAPMAP9970
Genomic Variants (DGV)NR1I3 [DGVbeta]
DECIPHER (Syndromes)1:161199456-161208000  ENSG00000143257
CONAN: Copy Number AnalysisNR1I3 
Mutations
ICGC Data PortalNR1I3 
TCGA Data PortalNR1I3 
Broad Tumor PortalNR1I3
OASIS PortalNR1I3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNR1I3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNR1I3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NR1I3
DgiDB (Drug Gene Interaction Database)NR1I3
DoCM (Curated mutations)NR1I3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NR1I3 (select a term)
intoGenNR1I3
Cancer3DNR1I3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603881   
Orphanet
MedgenNR1I3
Genetic Testing Registry NR1I3
NextProtQ14994 [Medical]
TSGene9970
GENETestsNR1I3
Huge Navigator NR1I3 [HugePedia]
snp3D : Map Gene to Disease9970
BioCentury BCIQNR1I3
ClinGenNR1I3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9970
Chemical/Pharm GKB GenePA391
Clinical trialNR1I3
Miscellaneous
canSAR (ICR)NR1I3 (select the gene name)
Probes
Litterature
PubMed103 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNR1I3
EVEXNR1I3
GoPubMedNR1I3
iHOPNR1I3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:19:19 CET 2017

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