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NR2E3 (nuclear receptor subfamily 2 group E member 3)

Identity

Other namesESCS
PNR
RNR
RP37
rd7
HGNC (Hugo) NR2E3
LocusID (NCBI) 10002
Atlas_Id 52606
Location 15q23  [Link to chromosome band 15q23]
Location_base_pair Starts at 72102888 and ends at 72110597 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NR2E3   7974
Cards
Entrez_Gene (NCBI)NR2E3  10002  nuclear receptor subfamily 2 group E member 3
AliasesESCS; PNR; RNR; RP37; 
rd7
GeneCards (Weizmann)NR2E3
Ensembl hg19 (Hinxton)ENSG00000278570 [Gene_View]  chr15:72102888-72110597 [Contig_View]  NR2E3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000278570 [Gene_View]  chr15:72102888-72110597 [Contig_View]  NR2E3 [Vega]
ICGC DataPortalENSG00000278570
TCGA cBioPortalNR2E3
AceView (NCBI)NR2E3
Genatlas (Paris)NR2E3
WikiGenes10002
SOURCE (Princeton)NR2E3
Genomic and cartography
GoldenPath hg19 (UCSC)NR2E3  -     chr15:72102888-72110597 +  15q23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NR2E3  -     15q23   [Description]    (hg38-Dec_2013)
EnsemblNR2E3 - 15q23 [CytoView hg19]  NR2E3 - 15q23 [CytoView hg38]
Mapping of homologs : NCBINR2E3 [Mapview hg19]  NR2E3 [Mapview hg38]
OMIM268100   604485   611131   
Gene and transcription
Genbank (Entrez)AB307710 AF121129 AF148128 AL711747 AW080977
RefSeq transcript (Entrez)NM_001281446 NM_014249 NM_016346
RefSeq genomic (Entrez)NC_000015 NC_018926 NG_009113 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)NR2E3
Cluster EST : UnigeneHs.636007 [ NCBI ]
CGAP (NCI)Hs.636007
Alternative Splicing GalleryENSG00000278570
Gene ExpressionNR2E3 [ NCBI-GEO ]   NR2E3 [ EBI - ARRAY_EXPRESS ]   NR2E3 [ SEEK ]   NR2E3 [ MEM ]
Gene Expression Viewer (FireBrowse)NR2E3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10002
GTEX Portal (Tissue expression)NR2E3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5X4 (Uniprot)
NextProtQ9Y5X4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5X4
Splice isoforms : SwissVarQ9Y5X4 (Swissvar)
PhosPhoSitePlusQ9Y5X4
Domaine pattern : Prosite (Expaxy)NUCLEAR_REC_DBD_1 (PS00031)    NUCLEAR_REC_DBD_2 (PS51030)   
Domains : Interpro (EBI)Nucl_hrmn_rcpt_lig-bd    Nuclear_hrmn_rcpt    Retinoid-X_rcpt/HNF4    Znf_hrmn_rcpt    Znf_NHR/GATA   
Domain families : Pfam (Sanger)Hormone_recep (PF00104)    zf-C4 (PF00105)   
Domain families : Pfam (NCBI)pfam00104    pfam00105   
Domain families : Smart (EMBL)HOLI (SM00430)  ZnF_C4 (SM00399)  
DMDM Disease mutations10002
Blocks (Seattle)NR2E3
PDB (SRS)4LOG   
PDB (PDBSum)4LOG   
PDB (IMB)4LOG   
PDB (RSDB)4LOG   
Structural Biology KnowledgeBase4LOG   
SCOP (Structural Classification of Proteins)4LOG   
CATH (Classification of proteins structures)4LOG   
SuperfamilyQ9Y5X4
Human Protein AtlasENSG00000278570
Peptide AtlasQ9Y5X4
HPRD05132
IPIIPI00001888   IPI00215922   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5X4
IntAct (EBI)Q9Y5X4
FunCoupENSG00000278570
BioGRIDNR2E3
STRING (EMBL)NR2E3
ZODIACNR2E3
Ontologies - Pathways
QuickGOQ9Y5X4
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  steroid hormone receptor activity  RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  transcription factor complex  transcription from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  signal transduction  visual perception  phototransduction  zinc ion binding  negative regulation of cell proliferation  intracellular receptor signaling pathway  eye photoreceptor cell development  steroid hormone mediated signaling pathway  sequence-specific DNA binding  positive regulation of rhodopsin gene expression  positive regulation of transcription from RNA polymerase II promoter  retina development in camera-type eye  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  steroid hormone receptor activity  RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  transcription factor complex  transcription from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  signal transduction  visual perception  phototransduction  zinc ion binding  negative regulation of cell proliferation  intracellular receptor signaling pathway  eye photoreceptor cell development  steroid hormone mediated signaling pathway  sequence-specific DNA binding  positive regulation of rhodopsin gene expression  positive regulation of transcription from RNA polymerase II promoter  retina development in camera-type eye  
NDEx NetworkNR2E3
Atlas of Cancer Signalling NetworkNR2E3
Wikipedia pathwaysNR2E3
Orthology - Evolution
OrthoDB10002
GeneTree (enSembl)ENSG00000278570
Phylogenetic Trees/Animal Genes : TreeFamNR2E3
Homologs : HomoloGeneNR2E3
Homology/Alignments : Family Browser (UCSC)NR2E3
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerNR2E3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NR2E3
dbVarNR2E3
ClinVarNR2E3
1000_GenomesNR2E3 
Exome Variant ServerNR2E3
ExAC (Exome Aggregation Consortium)NR2E3 (select the gene name)
Genetic variants : HAPMAP10002
Genomic Variants (DGV)NR2E3 [DGVbeta]
Mutations
ICGC Data PortalNR2E3 
TCGA Data PortalNR2E3 
Broad Tumor PortalNR2E3
OASIS PortalNR2E3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNR2E3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
BioMutasearch NR2E3
DgiDB (Drug Gene Interaction Database)NR2E3
DoCM (Curated mutations)NR2E3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NR2E3 (select a term)
intoGenNR2E3
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)15:72102888-72110597  ENSG00000278570
CONAN: Copy Number AnalysisNR2E3 
Mutations and Diseases : HGMDNR2E3
OMIM268100    604485    611131   
MedgenNR2E3
Genetic Testing Registry NR2E3
NextProtQ9Y5X4 [Medical]
TSGene10002
GENETestsNR2E3
Huge Navigator NR2E3 [HugePedia]
snp3D : Map Gene to Disease10002
BioCentury BCIQNR2E3
ClinGenNR2E3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10002
Chemical/Pharm GKB GenePA31757
Clinical trialNR2E3
Miscellaneous
canSAR (ICR)NR2E3 (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNR2E3
EVEXNR2E3
GoPubMedNR2E3
iHOPNR2E3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 19 19:05:11 CEST 2016

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