Atlas of Genetics and Cytogenetics in Oncology and Haematology


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NR2F1 (nuclear receptor subfamily 2 group F member 1)

Identity

Alias_namesERBAL3
TFCOUP1
nuclear receptor subfamily 2
Alias_symbol (synonym)EAR-3
COUP-TFI
TCFCOUP1
SVP44
Other aliasBBOAS
BBSOAS
EAR3
NR2F2
HGNC (Hugo) NR2F1
LocusID (NCBI) 7025
Atlas_Id 41571
Location 5q15  [Link to chromosome band 5q15]
Location_base_pair Starts at 93583337 and ends at 93594609 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LHX2 (9q33.3) / NR2F1 (5q15)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NR2F1   7975
Cards
Entrez_Gene (NCBI)NR2F1  7025  nuclear receptor subfamily 2 group F member 1
AliasesBBOAS; BBSOAS; COUP-TFI; EAR-3; 
EAR3; ERBAL3; NR2F2; SVP44; TCFCOUP1; TFCOUP1
GeneCards (Weizmann)NR2F1
Ensembl hg19 (Hinxton)ENSG00000175745 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175745 [Gene_View]  chr5:93583337-93594609 [Contig_View]  NR2F1 [Vega]
ICGC DataPortalENSG00000175745
TCGA cBioPortalNR2F1
AceView (NCBI)NR2F1
Genatlas (Paris)NR2F1
WikiGenes7025
SOURCE (Princeton)NR2F1
Genetics Home Reference (NIH)NR2F1
Genomic and cartography
GoldenPath hg38 (UCSC)NR2F1  -     chr5:93583337-93594609 +  5q15   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NR2F1  -     5q15   [Description]    (hg19-Feb_2009)
EnsemblNR2F1 - 5q15 [CytoView hg19]  NR2F1 - 5q15 [CytoView hg38]
Mapping of homologs : NCBINR2F1 [Mapview hg19]  NR2F1 [Mapview hg38]
OMIM132890   615722   
Gene and transcription
Genbank (Entrez)AF087978 BC004154 BC017493 HQ709180 HQ709181
RefSeq transcript (Entrez)NM_005654
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NR2F1
Cluster EST : UnigeneHs.519445 [ NCBI ]
CGAP (NCI)Hs.519445
Alternative Splicing GalleryENSG00000175745
Gene ExpressionNR2F1 [ NCBI-GEO ]   NR2F1 [ EBI - ARRAY_EXPRESS ]   NR2F1 [ SEEK ]   NR2F1 [ MEM ]
Gene Expression Viewer (FireBrowse)NR2F1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7025
GTEX Portal (Tissue expression)NR2F1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP10589   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP10589  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP10589
Splice isoforms : SwissVarP10589
PhosPhoSitePlusP10589
Domaine pattern : Prosite (Expaxy)NUCLEAR_REC_DBD_1 (PS00031)    NUCLEAR_REC_DBD_2 (PS51030)   
Domains : Interpro (EBI)COUP_TF    Nucl_hrmn_rcpt_lig-bd    Nuclear_hrmn_rcpt    Znf_hrmn_rcpt    Znf_NHR/GATA   
Domain families : Pfam (Sanger)Hormone_recep (PF00104)    zf-C4 (PF00105)   
Domain families : Pfam (NCBI)pfam00104    pfam00105   
Domain families : Smart (EMBL)HOLI (SM00430)  ZnF_C4 (SM00399)  
Conserved Domain (NCBI)NR2F1
DMDM Disease mutations7025
Blocks (Seattle)NR2F1
PDB (SRS)2EBL   
PDB (PDBSum)2EBL   
PDB (IMB)2EBL   
PDB (RSDB)2EBL   
Structural Biology KnowledgeBase2EBL   
SCOP (Structural Classification of Proteins)2EBL   
CATH (Classification of proteins structures)2EBL   
SuperfamilyP10589
Human Protein AtlasENSG00000175745
Peptide AtlasP10589
HPRD00584
IPIIPI00021431   
Protein Interaction databases
DIP (DOE-UCLA)P10589
IntAct (EBI)P10589
FunCoupENSG00000175745
BioGRIDNR2F1
STRING (EMBL)NR2F1
ZODIACNR2F1
Ontologies - Pathways
QuickGOP10589
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription factor activity, sequence-specific DNA binding  steroid hormone receptor activity  transcription coactivator activity  RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  transcription initiation from RNA polymerase II promoter  signal transduction  zinc ion binding  negative regulation of neuron projection development  intracellular receptor signaling pathway  steroid hormone mediated signaling pathway  sequence-specific DNA binding  retinoic acid-responsive element binding  positive regulation of transcription from RNA polymerase II promoter  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription factor activity, sequence-specific DNA binding  steroid hormone receptor activity  transcription coactivator activity  RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  transcription initiation from RNA polymerase II promoter  signal transduction  zinc ion binding  negative regulation of neuron projection development  intracellular receptor signaling pathway  steroid hormone mediated signaling pathway  sequence-specific DNA binding  retinoic acid-responsive element binding  positive regulation of transcription from RNA polymerase II promoter  
NDEx NetworkNR2F1
Atlas of Cancer Signalling NetworkNR2F1
Wikipedia pathwaysNR2F1
Orthology - Evolution
OrthoDB7025
GeneTree (enSembl)ENSG00000175745
Phylogenetic Trees/Animal Genes : TreeFamNR2F1
HOVERGENP10589
HOGENOMP10589
Homologs : HomoloGeneNR2F1
Homology/Alignments : Family Browser (UCSC)NR2F1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNR2F1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NR2F1
dbVarNR2F1
ClinVarNR2F1
1000_GenomesNR2F1 
Exome Variant ServerNR2F1
ExAC (Exome Aggregation Consortium)NR2F1 (select the gene name)
Genetic variants : HAPMAP7025
Genomic Variants (DGV)NR2F1 [DGVbeta]
DECIPHERNR2F1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNR2F1 
Mutations
ICGC Data PortalNR2F1 
TCGA Data PortalNR2F1 
Broad Tumor PortalNR2F1
OASIS PortalNR2F1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNR2F1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNR2F1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NR2F1
DgiDB (Drug Gene Interaction Database)NR2F1
DoCM (Curated mutations)NR2F1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NR2F1 (select a term)
intoGenNR2F1
Cancer3DNR2F1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM132890    615722   
Orphanet22827   
MedgenNR2F1
Genetic Testing Registry NR2F1
NextProtP10589 [Medical]
TSGene7025
GENETestsNR2F1
Target ValidationNR2F1
Huge Navigator NR2F1 [HugePedia]
snp3D : Map Gene to Disease7025
BioCentury BCIQNR2F1
ClinGenNR2F1 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7025
Chemical/Pharm GKB GenePA31758
Clinical trialNR2F1
Miscellaneous
canSAR (ICR)NR2F1 (select the gene name)
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNR2F1
EVEXNR2F1
GoPubMedNR2F1
iHOPNR2F1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:47:22 CEST 2017

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