Atlas of Genetics and Cytogenetics in Oncology and Haematology


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NR2F1 (nuclear receptor subfamily 2 group F member 1)

Identity

Alias (NCBI)BBOAS
BBSOAS
COUP-TFI
COUPTF1
EAR-3
EAR3
ERBAL3
SVP44
TCFCOUP1
TFCOUP1
HGNC (Hugo) NR2F1
HGNC Alias symbEAR-3
COUP-TFI
TCFCOUP1
SVP44
COUPTF1
HGNC Previous nameERBAL3
 TFCOUP1
HGNC Previous namenuclear receptor subfamily 2, group F, member 1
LocusID (NCBI) 7025
Atlas_Id 41571
Location 5q15  [Link to chromosome band 5q15]
Location_base_pair Starts at 93583222 and ends at 93594609 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LHX2 (9q33.3) / NR2F1 (5q15)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)NR2F1   7975
Cards
Entrez_Gene (NCBI)NR2F1    nuclear receptor subfamily 2 group F member 1
AliasesBBOAS; BBSOAS; COUP-TFI; COUPTF1; 
EAR-3; EAR3; ERBAL3; SVP44; TCFCOUP1; TFCOUP1
GeneCards (Weizmann)NR2F1
Ensembl hg19 (Hinxton)ENSG00000175745 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175745 [Gene_View]  ENSG00000175745 [Sequence]  chr5:93583222-93594609 [Contig_View]  NR2F1 [Vega]
ICGC DataPortalENSG00000175745
TCGA cBioPortalNR2F1
AceView (NCBI)NR2F1
Genatlas (Paris)NR2F1
SOURCE (Princeton)NR2F1
Genetics Home Reference (NIH)NR2F1
Genomic and cartography
GoldenPath hg38 (UCSC)NR2F1  -     chr5:93583222-93594609 +  5q15   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NR2F1  -     5q15   [Description]    (hg19-Feb_2009)
GoldenPathNR2F1 - 5q15 [CytoView hg19]  NR2F1 - 5q15 [CytoView hg38]
ImmunoBaseENSG00000175745
Genome Data Viewer NCBINR2F1 [Mapview hg19]  
OMIM132890   615722   
Gene and transcription
Genbank (Entrez)AF087978 BC004154 BC017493 HQ709180 HQ709181
RefSeq transcript (Entrez)NM_005654
Consensus coding sequences : CCDS (NCBI)NR2F1
Gene ExpressionNR2F1 [ NCBI-GEO ]   NR2F1 [ EBI - ARRAY_EXPRESS ]   NR2F1 [ SEEK ]   NR2F1 [ MEM ]
Gene Expression Viewer (FireBrowse)NR2F1 [ Firebrowse - Broad ]
GenevisibleExpression of NR2F1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7025
GTEX Portal (Tissue expression)NR2F1
Human Protein AtlasENSG00000175745-NR2F1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP10589   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP10589  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP10589
PhosPhoSitePlusP10589
Domaine pattern : Prosite (Expaxy)NR_LBD (PS51843)    NUCLEAR_REC_DBD_1 (PS00031)    NUCLEAR_REC_DBD_2 (PS51030)   
Domains : Interpro (EBI)NHR-like_dom_sf    Nucl_hrmn_rcpt_lig-bd    Nuclear_hrmn_rcpt    Znf_hrmn_rcpt    Znf_NHR/GATA   
Domain families : Pfam (Sanger)Hormone_recep (PF00104)    zf-C4 (PF00105)   
Domain families : Pfam (NCBI)pfam00104    pfam00105   
Domain families : Smart (EMBL)HOLI (SM00430)  ZnF_C4 (SM00399)  
Conserved Domain (NCBI)NR2F1
PDB (RSDB)2EBL   
PDB Europe2EBL   
PDB (PDBSum)2EBL   
PDB (IMB)2EBL   
Structural Biology KnowledgeBase2EBL   
SCOP (Structural Classification of Proteins)2EBL   
CATH (Classification of proteins structures)2EBL   
SuperfamilyP10589
AlphaFold pdb e-kbP10589   
Human Protein Atlas [tissue]ENSG00000175745-NR2F1 [tissue]
HPRD00584
Protein Interaction databases
DIP (DOE-UCLA)P10589
IntAct (EBI)P10589
BioGRIDNR2F1
STRING (EMBL)NR2F1
ZODIACNR2F1
Ontologies - Pathways
QuickGOP10589
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  negative regulation of transcription by RNA polymerase II  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  nuclear receptor activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytosol  regulation of transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  signal transduction  nervous system development  zinc ion binding  negative regulation of neuron projection development  cell differentiation  intracellular receptor signaling pathway  sequence-specific DNA binding  retinoic acid-responsive element binding  positive regulation of transcription by RNA polymerase II  anatomical structure development  sequence-specific double-stranded DNA binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  negative regulation of transcription by RNA polymerase II  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  nuclear receptor activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytosol  regulation of transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  signal transduction  nervous system development  zinc ion binding  negative regulation of neuron projection development  cell differentiation  intracellular receptor signaling pathway  sequence-specific DNA binding  retinoic acid-responsive element binding  positive regulation of transcription by RNA polymerase II  anatomical structure development  sequence-specific double-stranded DNA binding  
NDEx NetworkNR2F1
Atlas of Cancer Signalling NetworkNR2F1
Wikipedia pathwaysNR2F1
Orthology - Evolution
OrthoDB7025
GeneTree (enSembl)ENSG00000175745
Phylogenetic Trees/Animal Genes : TreeFamNR2F1
Homologs : HomoloGeneNR2F1
Homology/Alignments : Family Browser (UCSC)NR2F1
Gene fusions - Rearrangements
Fusion : QuiverNR2F1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNR2F1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NR2F1
dbVarNR2F1
ClinVarNR2F1
MonarchNR2F1
1000_GenomesNR2F1 
Exome Variant ServerNR2F1
GNOMAD BrowserENSG00000175745
Varsome BrowserNR2F1
ACMGNR2F1 variants
VarityP10589
Genomic Variants (DGV)NR2F1 [DGVbeta]
DECIPHERNR2F1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNR2F1 
Mutations
ICGC Data PortalNR2F1 
TCGA Data PortalNR2F1 
Broad Tumor PortalNR2F1
OASIS PortalNR2F1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNR2F1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNR2F1
Mutations and Diseases : HGMDNR2F1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNR2F1
DgiDB (Drug Gene Interaction Database)NR2F1
DoCM (Curated mutations)NR2F1
CIViC (Clinical Interpretations of Variants in Cancer)NR2F1
Cancer3DNR2F1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM132890    615722   
Orphanet22827   
DisGeNETNR2F1
MedgenNR2F1
Genetic Testing Registry NR2F1
NextProtP10589 [Medical]
GENETestsNR2F1
Target ValidationNR2F1
Huge Navigator NR2F1 [HugePedia]
ClinGenNR2F1 (curated)
Clinical trials, drugs, therapy
MyCancerGenomeNR2F1
Protein Interactions : CTDNR2F1
Pharm GKB GenePA31758
PharosP10589
Clinical trialNR2F1
Miscellaneous
canSAR (ICR)NR2F1
HarmonizomeNR2F1
DataMed IndexNR2F1
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNR2F1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:23:15 CEST 2021

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