NR2F1 (nuclear receptor subfamily 2 group F member 1)

2003-02-01  

Identity

HGNC
LOCATION
5q15
LOCUSID
ALIAS
BBOAS,BBSOAS,COUP-TFI,COUPTF1,EAR-3,EAR3,ERBAL3,SVP44,TCFCOUP1,TFCOUP1
FUSION GENES

Other Information

Locus ID:

NCBI: 7025
MIM: 132890
HGNC: 7975
Ensembl: ENSG00000175745

Variants:

dbSNP: 7025
ClinVar: 7025
TCGA: ENSG00000175745
COSMIC: NR2F1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175745ENST00000327111P10589
ENSG00000175745ENST00000615873F1DAL9
ENSG00000175745ENST00000647447F1DAL7

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Nuclear Receptor transcription pathwayREACTOMER-HSA-383280

References

Pubmed IDYearTitleCitations
195788762009The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations.39
203062912010A three-stage genome-wide association study of general cognitive ability: hunting the small effects.36
191121782009A chicken ovalbumin upstream promoter transcription factor I (COUP-TFI) complex represses expression of the gene encoding tumor necrosis factor alpha-induced protein 8 (TNFAIP8).24
244623722014NR2F1 mutations cause optic atrophy with intellectual disability.23
125519872003Distinct modes of regulation of transcription of hepatitis B virus by the nuclear receptors HNF4alpha and COUP-TF1.19
200079102010NR2F1 and IRE1beta suppress microsomal triglyceride transfer protein expression and lipoprotein assembly in undifferentiated intestinal epithelial cells.19
129726132003Repression of the luteinizing hormone receptor gene promoter by cross talk among EAR3/COUP-TFI, Sp1/Sp3, and TFIIB.18
201117032010Genome-wide analysis of binding sites and direct target genes of the orphan nuclear receptor NR2F1/COUP-TFI.16
120937452002Formation of an hER alpha-COUP-TFI complex enhances hER alpha AF-1 through Ser118 phosphorylation by MAPK.14
118119512002Transcriptional control of the human aldehyde dehydrogenase 2 promoter by hepatocyte nuclear factor 4: inhibition by cyclic AMP and COUP transcription factors.13

Citation

Dessen P

NR2F1 (nuclear receptor subfamily 2 group F member 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41571/nr2f1