| Nomenclature |
|---|
| HGNC (Hugo) | NR2F2 7976 |
| Cards |
|---|
| Entrez_Gene (NCBI) | NR2F2 7026 nuclear receptor subfamily 2 group F member 2 |
| Aliases | ARP1; CHTD4; COUPTFB; COUPTFII; |
| NF-E3; NR2F1; SVP40; TFCOUP2 |
| GeneCards (Weizmann) | NR2F2 |
| Ensembl hg19 (Hinxton) | ENSG00000185551 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000185551 [Gene_View] chr15:96325928-96340263 [Contig_View] NR2F2 [Vega] |
| ICGC DataPortal | ENSG00000185551 |
| TCGA cBioPortal | NR2F2 |
| AceView (NCBI) | NR2F2 |
| Genatlas (Paris) | NR2F2 |
| WikiGenes | 7026 |
| SOURCE (Princeton) | NR2F2 |
| Genetics Home Reference (NIH) | NR2F2 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | NR2F2 - chr15:96325928-96340263 + 15q26.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | NR2F2 - 15q26.2 [Description] (hg19-Feb_2009) |
| Ensembl | NR2F2 - 15q26.2 [CytoView hg19] NR2F2 - 15q26.2 [CytoView hg38] |
| Mapping of homologs : NCBI | NR2F2 [Mapview hg19] NR2F2 [Mapview hg38] |
| OMIM | 107773 615779 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AB307711 AF087993 AK298824 AK301595 AK316086 |
| RefSeq transcript (Entrez) | NM_001145155 NM_001145156 NM_001145157 NM_021005 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | NR2F2 |
| Cluster EST : Unigene | Hs.347991 [ NCBI ] |
| CGAP (NCI) | Hs.347991 |
| Alternative Splicing Gallery | ENSG00000185551 |
| Gene Expression | NR2F2 [ NCBI-GEO ] NR2F2 [ EBI - ARRAY_EXPRESS ]
NR2F2 [ SEEK ] NR2F2 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | NR2F2 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevisible | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 7026 |
| GTEX Portal (Tissue expression) | NR2F2 |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P24468 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P24468 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P24468 |
| Splice isoforms : SwissVar | P24468 |
| PhosPhoSitePlus | P24468 |
| Domaine pattern : Prosite (Expaxy) | NUCLEAR_REC_DBD_1 (PS00031) NUCLEAR_REC_DBD_2 (PS51030) |
| Domains : Interpro (EBI) | COUP_TF Nucl_hrmn_rcpt_lig-bd Nuclear_hrmn_rcpt Znf_hrmn_rcpt Znf_NHR/GATA |
| Domain families : Pfam (Sanger) | Hormone_recep (PF00104) zf-C4 (PF00105) |
| Domain families : Pfam (NCBI) | pfam00104 pfam00105 |
| Domain families : Smart (EMBL) | HOLI (SM00430) ZnF_C4 (SM00399) |
| Conserved Domain (NCBI) | NR2F2 |
| DMDM Disease mutations | 7026 |
| Blocks (Seattle) | NR2F2 |
| PDB (SRS) | 3CJW |
| PDB (PDBSum) | 3CJW |
| PDB (IMB) | 3CJW |
| PDB (RSDB) | 3CJW |
| Structural Biology KnowledgeBase | 3CJW |
| SCOP (Structural Classification of Proteins) | 3CJW |
| CATH (Classification of proteins structures) | 3CJW |
| Superfamily | P24468 |
| Human Protein Atlas | ENSG00000185551 |
| Peptide Atlas | P24468 |
| HPRD | 00139 |
| IPI | IPI00028611 IPI00921868 IPI00789037 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P24468 |
| IntAct (EBI) | P24468 |
| FunCoup | ENSG00000185551 |
| BioGRID | NR2F2 |
| STRING (EMBL) | NR2F2 |
| ZODIAC | NR2F2 |
| Ontologies - Pathways |
|---|
| QuickGO | P24468 |
| Ontology : AmiGO | negative regulation of transcription from RNA polymerase II promoter neuron migration maternal placenta development negative regulation of endothelial cell proliferation retinoic acid binding positive regulation of systemic arterial blood pressure transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity transcription corepressor activity RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding protein binding nucleus transcription, DNA-templated regulation of transcription from RNA polymerase II promoter lipid metabolic process signal transduction skeletal muscle tissue development zinc ion binding fertilization anterior/posterior pattern specification radial pattern formation negative regulation of endothelial cell migration intracellular receptor signaling pathway forebrain development response to estradiol protein homodimerization activity steroid hormone mediated signaling pathway sequence-specific DNA binding negative regulation of cyclin-dependent protein serine/threonine kinase activity negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated blood vessel morphogenesis limb development placenta blood vessel development trophoblast giant cell differentiation regulation of transcription involved in lymphatic endothelial cell fate commitment |
| Ontology : EGO-EBI | negative regulation of transcription from RNA polymerase II promoter neuron migration maternal placenta development negative regulation of endothelial cell proliferation retinoic acid binding positive regulation of systemic arterial blood pressure transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity transcription corepressor activity RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding protein binding nucleus transcription, DNA-templated regulation of transcription from RNA polymerase II promoter lipid metabolic process signal transduction skeletal muscle tissue development zinc ion binding fertilization anterior/posterior pattern specification radial pattern formation negative regulation of endothelial cell migration intracellular receptor signaling pathway forebrain development response to estradiol protein homodimerization activity steroid hormone mediated signaling pathway sequence-specific DNA binding negative regulation of cyclin-dependent protein serine/threonine kinase activity negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated blood vessel morphogenesis limb development placenta blood vessel development trophoblast giant cell differentiation regulation of transcription involved in lymphatic endothelial cell fate commitment |
| NDEx Network | NR2F2 |
| Atlas of Cancer Signalling Network | NR2F2 |
| Wikipedia pathways | NR2F2 |
| Orthology - Evolution |
|---|
| OrthoDB | 7026 |
| GeneTree (enSembl) | ENSG00000185551 |
| Phylogenetic Trees/Animal Genes : TreeFam | NR2F2 |
| HOVERGEN | P24468 |
| HOGENOM | P24468 |
| Homologs : HomoloGene | NR2F2 |
| Homology/Alignments : Family Browser (UCSC) | NR2F2 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | NR2F2/MSI2 [15q26.2/17q22] |
| Fusion: TCGA | NR2F2 15q26.2 MSI2 17q22 BRCA |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | NR2F2 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | NR2F2 |
| dbVar | NR2F2 |
| ClinVar | NR2F2 |
| 1000_Genomes | NR2F2 |
| Exome Variant Server | NR2F2 |
| ExAC (Exome Aggregation Consortium) | NR2F2 (select the gene name) |
| Genetic variants : HAPMAP | 7026 |
| Genomic Variants (DGV) | NR2F2 [DGVbeta] |
| DECIPHER | NR2F2 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | NR2F2 |
| Mutations |
|---|
| ICGC Data Portal | NR2F2 |
| TCGA Data Portal | NR2F2 |
| Broad Tumor Portal | NR2F2 |
| OASIS Portal | NR2F2 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | NR2F2 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | NR2F2 |
| intOGen Portal | NR2F2 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search NR2F2 |
| DgiDB (Drug Gene Interaction Database) | NR2F2 |
| DoCM (Curated mutations) | NR2F2 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | NR2F2 (select a term) |
| intoGen | NR2F2 |
| Cancer3D | NR2F2(select the gene name) |
| Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 107773 615779 |
| Orphanet | 871 8597 |
| Medgen | NR2F2 |
| Genetic Testing Registry | NR2F2
|
| NextProt | P24468 [Medical] |
| TSGene | 7026 |
| GENETests | NR2F2 |
| Target Validation | NR2F2 |
| Huge Navigator |
NR2F2 [HugePedia] |
| snp3D : Map Gene to Disease | 7026 |
| BioCentury BCIQ | NR2F2 |
| ClinGen | NR2F2 (curated) |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 7026 |
| Chemical/Pharm GKB Gene | PA31759 |
| Clinical trial | NR2F2 |
| Miscellaneous |
|---|
| canSAR (ICR) | NR2F2 (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 79 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | NR2F2 |
| EVEX | NR2F2 |
| GoPubMed | NR2F2 |
| iHOP | NR2F2 |
