Atlas of Genetics and Cytogenetics in Oncology and Haematology

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NR2F2 (nuclear receptor subfamily 2 group F member 2)

Identity

Alias (NCBI)ARP-1
ARP1
CHTD4
COUPTF2
COUPTFB
COUPTFII
NF-E3
SRXX5
SVP40
TFCOUP2
HGNC (Hugo) NR2F2
HGNC Alias symbCOUP-TFII
COUPTFB
SVP40
NF-E3
COUPTF2
HGNC Previous nameARP1
 TFCOUP2
HGNC Previous namenuclear receptor subfamily 2, group F, member 2
LocusID (NCBI) 7026
Atlas_Id 47203
Location 15q26.2  [Link to chromosome band 15q26]
Location_base_pair Starts at 96330700 and ends at 96340256 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NR2F2 (15q26.2) / MRTO4 (1p36.13)NR2F2 (15q26.2) / MSI2 (17q22)NR2F2 (15q26.2) / NR2F2 (15q26.2)
NR2F2 15q26.2 / MSI2 17q22

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NR2F2   7976
Cards
Entrez_Gene (NCBI)NR2F2    nuclear receptor subfamily 2 group F member 2
AliasesARP-1; ARP1; CHTD4; COUPTF2; 
COUPTFB; COUPTFII; NF-E3; SRXX5; SVP40; TFCOUP2
GeneCards (Weizmann)NR2F2
Ensembl hg19 (Hinxton)ENSG00000185551 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185551 [Gene_View]  ENSG00000185551 [Sequence]  chr15:96330700-96340256 [Contig_View]  NR2F2 [Vega]
ICGC DataPortalENSG00000185551
TCGA cBioPortalNR2F2
AceView (NCBI)NR2F2
Genatlas (Paris)NR2F2
SOURCE (Princeton)NR2F2
Genetics Home Reference (NIH)NR2F2
Genomic and cartography
GoldenPath hg38 (UCSC)NR2F2  -     chr15:96330700-96340256 +  15q26.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NR2F2  -     15q26.2   [Description]    (hg19-Feb_2009)
GoldenPathNR2F2 - 15q26.2 [CytoView hg19]  NR2F2 - 15q26.2 [CytoView hg38]
ImmunoBaseENSG00000185551
genome Data Viewer NCBINR2F2 [Mapview hg19]  
OMIM107773   615779   618901   
Gene and transcription
Genbank (Entrez)AB307711 AF087993 AK298824 AK301595 AK316086
RefSeq transcript (Entrez)NM_001145155 NM_001145156 NM_001145157 NM_021005
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NR2F2
Alternative Splicing GalleryENSG00000185551
Gene ExpressionNR2F2 [ NCBI-GEO ]   NR2F2 [ EBI - ARRAY_EXPRESS ]   NR2F2 [ SEEK ]   NR2F2 [ MEM ]
Gene Expression Viewer (FireBrowse)NR2F2 [ Firebrowse - Broad ]
GenevisibleExpression of NR2F2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7026
GTEX Portal (Tissue expression)NR2F2
Human Protein AtlasENSG00000185551-NR2F2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP24468   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP24468  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP24468
Splice isoforms : SwissVarP24468
PhosPhoSitePlusP24468
Domaine pattern : Prosite (Expaxy)NR_LBD (PS51843)    NUCLEAR_REC_DBD_1 (PS00031)    NUCLEAR_REC_DBD_2 (PS51030)   
Domains : Interpro (EBI)NHR-like_dom_sf    Nucl_hrmn_rcpt_lig-bd    Nuclear_hrmn_rcpt    Znf_hrmn_rcpt    Znf_NHR/GATA   
Domain families : Pfam (Sanger)Hormone_recep (PF00104)    zf-C4 (PF00105)   
Domain families : Pfam (NCBI)pfam00104    pfam00105   
Domain families : Smart (EMBL)HOLI (SM00430)  ZnF_C4 (SM00399)  
Conserved Domain (NCBI)NR2F2
Blocks (Seattle)NR2F2
PDB (RSDB)3CJW   
PDB Europe3CJW   
PDB (PDBSum)3CJW   
PDB (IMB)3CJW   
Structural Biology KnowledgeBase3CJW   
SCOP (Structural Classification of Proteins)3CJW   
CATH (Classification of proteins structures)3CJW   
SuperfamilyP24468
Human Protein Atlas [tissue]ENSG00000185551-NR2F2 [tissue]
Peptide AtlasP24468
HPRD00139
IPIIPI00028611   IPI00921868   IPI00789037   
Protein Interaction databases
DIP (DOE-UCLA)P24468
IntAct (EBI)P24468
BioGRIDNR2F2
STRING (EMBL)NR2F2
ZODIACNR2F2
Ontologies - Pathways
QuickGOP24468
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  negative regulation of transcription by RNA polymerase II  RNA polymerase II cis-regulatory region sequence-specific DNA binding  neuron migration  maternal placenta development  negative regulation of endothelial cell proliferation  retinoic acid binding  retinoic acid binding  positive regulation of systemic arterial blood pressure  DNA-binding transcription factor activity  nuclear receptor activity  nuclear receptor activity  protein binding  nucleus  nucleoplasm  cytosol  regulation of transcription by RNA polymerase II  skeletal muscle tissue development  zinc ion binding  fertilization  anterior/posterior pattern specification  radial pattern formation  negative regulation of endothelial cell migration  cell differentiation  intracellular receptor signaling pathway  forebrain development  response to estradiol  protein homodimerization activity  sequence-specific DNA binding  negative regulation of cyclin-dependent protein serine/threonine kinase activity  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  blood vessel morphogenesis  anatomical structure development  limb development  placenta blood vessel development  trophoblast giant cell differentiation  lymphatic endothelial cell fate commitment  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  negative regulation of transcription by RNA polymerase II  RNA polymerase II cis-regulatory region sequence-specific DNA binding  neuron migration  maternal placenta development  negative regulation of endothelial cell proliferation  retinoic acid binding  retinoic acid binding  positive regulation of systemic arterial blood pressure  DNA-binding transcription factor activity  nuclear receptor activity  nuclear receptor activity  protein binding  nucleus  nucleoplasm  cytosol  regulation of transcription by RNA polymerase II  skeletal muscle tissue development  zinc ion binding  fertilization  anterior/posterior pattern specification  radial pattern formation  negative regulation of endothelial cell migration  cell differentiation  intracellular receptor signaling pathway  forebrain development  response to estradiol  protein homodimerization activity  sequence-specific DNA binding  negative regulation of cyclin-dependent protein serine/threonine kinase activity  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  blood vessel morphogenesis  anatomical structure development  limb development  placenta blood vessel development  trophoblast giant cell differentiation  lymphatic endothelial cell fate commitment  
NDEx NetworkNR2F2
Atlas of Cancer Signalling NetworkNR2F2
Wikipedia pathwaysNR2F2
Orthology - Evolution
OrthoDB7026
GeneTree (enSembl)ENSG00000185551
Phylogenetic Trees/Animal Genes : TreeFamNR2F2
HOGENOMP24468
Homologs : HomoloGeneNR2F2
Homology/Alignments : Family Browser (UCSC)NR2F2
Gene fusions - Rearrangements
Fusion : MitelmanNR2F2/MSI2 [15q26.2/17q22]  
Fusion PortalNR2F2 15q26.2 MSI2 17q22 BRCA
Fusion : QuiverNR2F2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNR2F2 [hg38]
dbVarNR2F2
ClinVarNR2F2
MonarchNR2F2
1000_GenomesNR2F2 
Exome Variant ServerNR2F2
GNOMAD BrowserENSG00000185551
Varsome BrowserNR2F2
Genomic Variants (DGV)NR2F2 [DGVbeta]
DECIPHERNR2F2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNR2F2 
Mutations
ICGC Data PortalNR2F2 
TCGA Data PortalNR2F2 
Broad Tumor PortalNR2F2
OASIS PortalNR2F2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNR2F2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNR2F2
Mutations and Diseases : HGMDNR2F2
intOGen PortalNR2F2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NR2F2
DgiDB (Drug Gene Interaction Database)NR2F2
DoCM (Curated mutations)NR2F2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NR2F2 (select a term)
intoGenNR2F2
Cancer3DNR2F2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM107773    615779    618901   
Orphanet871    8597   
DisGeNETNR2F2
MedgenNR2F2
Genetic Testing Registry NR2F2
NextProtP24468 [Medical]
GENETestsNR2F2
Target ValidationNR2F2
Huge Navigator NR2F2 [HugePedia]
ClinGenNR2F2 (curated)
Clinical trials, drugs, therapy
MyCancerGenomeNR2F2
Protein Interactions : CTD
Pharm GKB GenePA31759
PharosP24468
Clinical trialNR2F2
Miscellaneous
canSAR (ICR)NR2F2 (select the gene name)
HarmonizomeNR2F2
DataMed IndexNR2F2
Probes
Litterature
PubMed127 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNR2F2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Mar 25 19:37:06 CET 2021
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