Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NRBP1 (nuclear receptor binding protein 1)

Identity

Alias_namesNRBP
nuclear receptor binding protein
Alias_symbol (synonym)BCON3
MUDPNP
MADM
Other alias
HGNC (Hugo) NRBP1
LocusID (NCBI) 29959
Atlas_Id 45720
Location 2p23.3  [Link to chromosome band 2p23]
Location_base_pair Starts at 27427790 and ends at 27442257 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DAPK1 (9q21.33) / NRBP1 (2p23.3)NRBP1 (2p23.3) / NRBP1 (2p23.3)NRBP1 (2p23.3) / PRRC2A (6p21.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NRBP1   7993
Cards
Entrez_Gene (NCBI)NRBP1  29959  nuclear receptor binding protein 1
AliasesBCON3; MADM; MUDPNP; NRBP
GeneCards (Weizmann)NRBP1
Ensembl hg19 (Hinxton)ENSG00000115216 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115216 [Gene_View]  chr2:27427790-27442257 [Contig_View]  NRBP1 [Vega]
ICGC DataPortalENSG00000115216
TCGA cBioPortalNRBP1
AceView (NCBI)NRBP1
Genatlas (Paris)NRBP1
WikiGenes29959
SOURCE (Princeton)NRBP1
Genetics Home Reference (NIH)NRBP1
Genomic and cartography
GoldenPath hg38 (UCSC)NRBP1  -     chr2:27427790-27442257 +  2p23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NRBP1  -     2p23.3   [Description]    (hg19-Feb_2009)
EnsemblNRBP1 - 2p23.3 [CytoView hg19]  NRBP1 - 2p23.3 [CytoView hg38]
Mapping of homologs : NCBINRBP1 [Mapview hg19]  NRBP1 [Mapview hg38]
OMIM606010   
Gene and transcription
Genbank (Entrez)AF113249 AK001946 AK027538 AK092860 AK122664
RefSeq transcript (Entrez)NM_001321357 NM_001321358 NM_001321359 NM_001321361 NM_001321362 NM_001321363 NM_013392
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NRBP1
Cluster EST : UnigeneHs.515876 [ NCBI ]
CGAP (NCI)Hs.515876
Alternative Splicing GalleryENSG00000115216
Gene ExpressionNRBP1 [ NCBI-GEO ]   NRBP1 [ EBI - ARRAY_EXPRESS ]   NRBP1 [ SEEK ]   NRBP1 [ MEM ]
Gene Expression Viewer (FireBrowse)NRBP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29959
GTEX Portal (Tissue expression)NRBP1
Human Protein AtlasENSG00000115216-NRBP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UHY1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UHY1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UHY1
Splice isoforms : SwissVarQ9UHY1
PhosPhoSitePlusQ9UHY1
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_DOM (PS50011)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Ser-Thr/Tyr_kinase_cat_dom   
Domain families : Pfam (Sanger)Pkinase_Tyr (PF07714)   
Domain families : Pfam (NCBI)pfam07714   
Conserved Domain (NCBI)NRBP1
DMDM Disease mutations29959
Blocks (Seattle)NRBP1
SuperfamilyQ9UHY1
Human Protein Atlas [tissue]ENSG00000115216-NRBP1 [tissue]
Peptide AtlasQ9UHY1
HPRD05819
IPIIPI00604756   IPI01014543   IPI00893743   IPI00893598   IPI00894537   
Protein Interaction databases
DIP (DOE-UCLA)Q9UHY1
IntAct (EBI)Q9UHY1
FunCoupENSG00000115216
BioGRIDNRBP1
STRING (EMBL)NRBP1
ZODIACNRBP1
Ontologies - Pathways
QuickGOQ9UHY1
Ontology : AmiGOprotein serine/threonine kinase activity  protein binding  ATP binding  nucleoplasm  cytosol  cell cortex  transcription initiation from RNA polymerase II promoter  protein phosphorylation  ER to Golgi vesicle-mediated transport  endomembrane system  membrane  lamellipodium  intracellular signal transduction  protein homodimerization activity  
Ontology : EGO-EBIprotein serine/threonine kinase activity  protein binding  ATP binding  nucleoplasm  cytosol  cell cortex  transcription initiation from RNA polymerase II promoter  protein phosphorylation  ER to Golgi vesicle-mediated transport  endomembrane system  membrane  lamellipodium  intracellular signal transduction  protein homodimerization activity  
NDEx NetworkNRBP1
Atlas of Cancer Signalling NetworkNRBP1
Wikipedia pathwaysNRBP1
Orthology - Evolution
OrthoDB29959
GeneTree (enSembl)ENSG00000115216
Phylogenetic Trees/Animal Genes : TreeFamNRBP1
HOVERGENQ9UHY1
HOGENOMQ9UHY1
Homologs : HomoloGeneNRBP1
Homology/Alignments : Family Browser (UCSC)NRBP1
Gene fusions - Rearrangements
Tumor Fusion PortalNRBP1
Fusion Cancer (Beijing)NRBP1 [2p23.3]  -  PRRC2A [6p21.33]  [FUSC002232]  [FUSC002232]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNRBP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NRBP1
dbVarNRBP1
ClinVarNRBP1
1000_GenomesNRBP1 
Exome Variant ServerNRBP1
ExAC (Exome Aggregation Consortium)ENSG00000115216
GNOMAD BrowserENSG00000115216
Genetic variants : HAPMAP29959
Genomic Variants (DGV)NRBP1 [DGVbeta]
DECIPHERNRBP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNRBP1 
Mutations
ICGC Data PortalNRBP1 
TCGA Data PortalNRBP1 
Broad Tumor PortalNRBP1
OASIS PortalNRBP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNRBP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNRBP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NRBP1
DgiDB (Drug Gene Interaction Database)NRBP1
DoCM (Curated mutations)NRBP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NRBP1 (select a term)
intoGenNRBP1
Cancer3DNRBP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606010   
Orphanet
DisGeNETNRBP1
MedgenNRBP1
Genetic Testing Registry NRBP1
NextProtQ9UHY1 [Medical]
TSGene29959
GENETestsNRBP1
Target ValidationNRBP1
Huge Navigator NRBP1 [HugePedia]
snp3D : Map Gene to Disease29959
BioCentury BCIQNRBP1
ClinGenNRBP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29959
Chemical/Pharm GKB GenePA31772
Clinical trialNRBP1
Miscellaneous
canSAR (ICR)NRBP1 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNRBP1
EVEXNRBP1
GoPubMedNRBP1
iHOPNRBP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:26:46 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.