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NRBP2 (nuclear receptor binding protein 2)

Identity

Alias_symbol (synonym)DKFZp434P086
Other aliasTRG16
pp9320
HGNC (Hugo) NRBP2
LocusID (NCBI) 340371
Atlas_Id 43384
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 143833585 and ends at 143840974 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NPIPB7 (16q23.1) / NRBP2 (8q24.3)NRBP2 (8q24.3) / VPS28 (8q24.3)SCRIB (8q24.3) / NRBP2 (8q24.3)
SCRIB 8q24.3 / NRBP2 8q24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NRBP2   19339
Cards
Entrez_Gene (NCBI)NRBP2  340371  nuclear receptor binding protein 2
AliasesTRG16; pp9320
GeneCards (Weizmann)NRBP2
Ensembl hg19 (Hinxton)ENSG00000185189 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185189 [Gene_View]  chr8:143833585-143840974 [Contig_View]  NRBP2 [Vega]
ICGC DataPortalENSG00000185189
TCGA cBioPortalNRBP2
AceView (NCBI)NRBP2
Genatlas (Paris)NRBP2
WikiGenes340371
SOURCE (Princeton)NRBP2
Genetics Home Reference (NIH)NRBP2
Genomic and cartography
GoldenPath hg38 (UCSC)NRBP2  -     chr8:143833585-143840974 -  8q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NRBP2  -     8q24.3   [Description]    (hg19-Feb_2009)
EnsemblNRBP2 - 8q24.3 [CytoView hg19]  NRBP2 - 8q24.3 [CytoView hg38]
Mapping of homologs : NCBINRBP2 [Mapview hg19]  NRBP2 [Mapview hg38]
OMIM615563   
Gene and transcription
Genbank (Entrez)AF318376 AI094905 AK094017 AK293943 AK308967
RefSeq transcript (Entrez)NM_178564
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NRBP2
Cluster EST : UnigeneHs.521926 [ NCBI ]
CGAP (NCI)Hs.521926
Alternative Splicing GalleryENSG00000185189
Gene ExpressionNRBP2 [ NCBI-GEO ]   NRBP2 [ EBI - ARRAY_EXPRESS ]   NRBP2 [ SEEK ]   NRBP2 [ MEM ]
Gene Expression Viewer (FireBrowse)NRBP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)340371
GTEX Portal (Tissue expression)NRBP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NSY0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NSY0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NSY0
Splice isoforms : SwissVarQ9NSY0
PhosPhoSitePlusQ9NSY0
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_DOM (PS50011)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Conserved Domain (NCBI)NRBP2
DMDM Disease mutations340371
Blocks (Seattle)NRBP2
SuperfamilyQ9NSY0
Human Protein AtlasENSG00000185189
Peptide AtlasQ9NSY0
HPRD14838
IPIIPI00383275   IPI00168489   IPI00964924   IPI00965220   IPI00942339   IPI00978947   IPI00978344   
Protein Interaction databases
DIP (DOE-UCLA)Q9NSY0
IntAct (EBI)Q9NSY0
FunCoupENSG00000185189
BioGRIDNRBP2
STRING (EMBL)NRBP2
ZODIACNRBP2
Ontologies - Pathways
QuickGOQ9NSY0
Ontology : AmiGOprotein serine/threonine kinase activity  ATP binding  cytoplasm  cytosol  protein phosphorylation  ER to Golgi vesicle-mediated transport  endomembrane system  negative regulation of macroautophagy  neuron differentiation  intracellular signal transduction  negative regulation of neuron apoptotic process  
Ontology : EGO-EBIprotein serine/threonine kinase activity  ATP binding  cytoplasm  cytosol  protein phosphorylation  ER to Golgi vesicle-mediated transport  endomembrane system  negative regulation of macroautophagy  neuron differentiation  intracellular signal transduction  negative regulation of neuron apoptotic process  
NDEx NetworkNRBP2
Atlas of Cancer Signalling NetworkNRBP2
Wikipedia pathwaysNRBP2
Orthology - Evolution
OrthoDB340371
GeneTree (enSembl)ENSG00000185189
Phylogenetic Trees/Animal Genes : TreeFamNRBP2
HOVERGENQ9NSY0
HOGENOMQ9NSY0
Homologs : HomoloGeneNRBP2
Homology/Alignments : Family Browser (UCSC)NRBP2
Gene fusions - Rearrangements
Fusion : MitelmanNRBP2/VPS28 [8q24.3/8q24.3]  
Fusion : MitelmanSCRIB/NRBP2 [8q24.3/8q24.3]  [t(8;8)(q24;q24)]  
Fusion: TCGASCRIB 8q24.3 NRBP2 8q24.3 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNRBP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NRBP2
dbVarNRBP2
ClinVarNRBP2
1000_GenomesNRBP2 
Exome Variant ServerNRBP2
ExAC (Exome Aggregation Consortium)NRBP2 (select the gene name)
Genetic variants : HAPMAP340371
Genomic Variants (DGV)NRBP2 [DGVbeta]
DECIPHERNRBP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNRBP2 
Mutations
ICGC Data PortalNRBP2 
TCGA Data PortalNRBP2 
Broad Tumor PortalNRBP2
OASIS PortalNRBP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNRBP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNRBP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NRBP2
DgiDB (Drug Gene Interaction Database)NRBP2
DoCM (Curated mutations)NRBP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NRBP2 (select a term)
intoGenNRBP2
Cancer3DNRBP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615563   
Orphanet
MedgenNRBP2
Genetic Testing Registry NRBP2
NextProtQ9NSY0 [Medical]
TSGene340371
GENETestsNRBP2
Target ValidationNRBP2
Huge Navigator NRBP2 [HugePedia]
snp3D : Map Gene to Disease340371
BioCentury BCIQNRBP2
ClinGenNRBP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD340371
Chemical/Pharm GKB GenePA134891143
Clinical trialNRBP2
Miscellaneous
canSAR (ICR)NRBP2 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNRBP2
EVEXNRBP2
GoPubMedNRBP2
iHOPNRBP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:47:24 CEST 2017

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