Atlas of Genetics and Cytogenetics in Oncology and Haematology

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NRGN (neurogranin)

Identity

Alias (NCBI)RC3
hng
HGNC (Hugo) NRGN
HGNC Alias symbRC3
HGNC Previous nameneurogranin (protein kinase C substrate, RC3)
LocusID (NCBI) 4900
Atlas_Id 70969
Location 11q24.2  [Link to chromosome band 11q24]
Location_base_pair Starts at 124739933 and ends at 124747206 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NRGN (11q24.2) / HRH3 (20q13.33)NRGN (11q24.2) / RPL8 (8q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NRGN   8000
Cards
Entrez_Gene (NCBI)NRGN    neurogranin
AliasesRC3; hng
GeneCards (Weizmann)NRGN
Ensembl hg19 (Hinxton)ENSG00000154146 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000154146 [Gene_View]  ENSG00000154146 [Sequence]  chr11:124739933-124747206 [Contig_View]  NRGN [Vega]
ICGC DataPortalENSG00000154146
TCGA cBioPortalNRGN
AceView (NCBI)NRGN
Genatlas (Paris)NRGN
SOURCE (Princeton)NRGN
Genetics Home Reference (NIH)NRGN
Genomic and cartography
GoldenPath hg38 (UCSC)NRGN  -     chr11:124739933-124747206 +  11q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NRGN  -     11q24.2   [Description]    (hg19-Feb_2009)
GoldenPathNRGN - 11q24.2 [CytoView hg19]  NRGN - 11q24.2 [CytoView hg38]
ImmunoBaseENSG00000154146
genome Data Viewer NCBINRGN [Mapview hg19]  
OMIM602350   
Gene and transcription
Genbank (Entrez)BC002835 BM923818 BT007325 DB474181 U89165
RefSeq transcript (Entrez)NM_001126181 NM_006176
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NRGN
Alternative Splicing GalleryENSG00000154146
Gene ExpressionNRGN [ NCBI-GEO ]   NRGN [ EBI - ARRAY_EXPRESS ]   NRGN [ SEEK ]   NRGN [ MEM ]
Gene Expression Viewer (FireBrowse)NRGN [ Firebrowse - Broad ]
GenevisibleExpression of NRGN in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4900
GTEX Portal (Tissue expression)NRGN
Human Protein AtlasENSG00000154146-NRGN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92686   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92686  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92686
Splice isoforms : SwissVarQ92686
PhosPhoSitePlusQ92686
Domaine pattern : Prosite (Expaxy)IQ (PS50096)   
Domains : Interpro (EBI)IQ_motif_EF-hand-BS   
Domain families : Pfam (Sanger)IQ (PF00612)   
Domain families : Pfam (NCBI)pfam00612   
Domain families : Smart (EMBL)IQ (SM00015)  
Conserved Domain (NCBI)NRGN
Blocks (Seattle)NRGN
SuperfamilyQ92686
Human Protein Atlas [tissue]ENSG00000154146-NRGN [tissue]
Peptide AtlasQ92686
HPRD03828
IPIIPI00022640   
Protein Interaction databases
DIP (DOE-UCLA)Q92686
IntAct (EBI)Q92686
BioGRIDNRGN
STRING (EMBL)NRGN
ZODIACNRGN
Ontologies - Pathways
QuickGOQ92686
Ontology : AmiGOcalmodulin binding  phosphatidylinositol-3,4,5-trisphosphate binding  nucleus  cytoplasm  cytosol  signal transduction  nervous system development  associative learning  trans-Golgi network transport vesicle membrane  postsynaptic density  telencephalon development  axon  mitochondrial membrane  neuronal cell body  dendritic spine head  postsynaptic membrane  phosphatidic acid binding  glutamatergic synapse  postsynaptic modulation of chemical synaptic transmission  positive regulation of long-term synaptic potentiation  
Ontology : EGO-EBIcalmodulin binding  phosphatidylinositol-3,4,5-trisphosphate binding  nucleus  cytoplasm  cytosol  signal transduction  nervous system development  associative learning  trans-Golgi network transport vesicle membrane  postsynaptic density  telencephalon development  axon  mitochondrial membrane  neuronal cell body  dendritic spine head  postsynaptic membrane  phosphatidic acid binding  glutamatergic synapse  postsynaptic modulation of chemical synaptic transmission  positive regulation of long-term synaptic potentiation  
NDEx NetworkNRGN
Atlas of Cancer Signalling NetworkNRGN
Wikipedia pathwaysNRGN
Orthology - Evolution
OrthoDB4900
GeneTree (enSembl)ENSG00000154146
Phylogenetic Trees/Animal Genes : TreeFamNRGN
HOGENOMQ92686
Homologs : HomoloGeneNRGN
Homology/Alignments : Family Browser (UCSC)NRGN
Gene fusions - Rearrangements
Fusion : QuiverNRGN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNRGN [hg38]
dbVarNRGN
ClinVarNRGN
MonarchNRGN
1000_GenomesNRGN 
Exome Variant ServerNRGN
GNOMAD BrowserENSG00000154146
Varsome BrowserNRGN
Genomic Variants (DGV)NRGN [DGVbeta]
DECIPHERNRGN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNRGN 
Mutations
ICGC Data PortalNRGN 
TCGA Data PortalNRGN 
Broad Tumor PortalNRGN
OASIS PortalNRGN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNRGN  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNRGN
Mutations and Diseases : HGMDNRGN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NRGN
DgiDB (Drug Gene Interaction Database)NRGN
DoCM (Curated mutations)NRGN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NRGN (select a term)
intoGenNRGN
Cancer3DNRGN(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602350   
Orphanet
DisGeNETNRGN
MedgenNRGN
Genetic Testing Registry NRGN
NextProtQ92686 [Medical]
GENETestsNRGN
Target ValidationNRGN
Huge Navigator NRGN [HugePedia]
ClinGenNRGN
Clinical trials, drugs, therapy
MyCancerGenomeNRGN
Protein Interactions : CTD
Pharm GKB GenePA31779
Clinical trialNRGN
Miscellaneous
canSAR (ICR)NRGN (select the gene name)
HarmonizomeNRGN
DataMed IndexNRGN
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNRGN
EVEXNRGN
GoPubMedNRGN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 17:19:30 CET 2020
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