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NRGN (neurogranin)

Identity

Alias_namesneurogranin (protein kinase C substrate, RC3)
Alias_symbol (synonym)RC3
Other aliashng
HGNC (Hugo) NRGN
LocusID (NCBI) 4900
Atlas_Id 70969
Location 11q24.2  [Link to chromosome band 11q24]
Location_base_pair Starts at 124739933 and ends at 124747206 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NRGN (11q24.2) / HRH3 (20q13.33)NRGN (11q24.2) / RPL8 (8q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NRGN   8000
Cards
Entrez_Gene (NCBI)NRGN  4900  neurogranin
AliasesRC3; hng
GeneCards (Weizmann)NRGN
Ensembl hg19 (Hinxton)ENSG00000154146 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000154146 [Gene_View]  chr11:124739933-124747206 [Contig_View]  NRGN [Vega]
ICGC DataPortalENSG00000154146
TCGA cBioPortalNRGN
AceView (NCBI)NRGN
Genatlas (Paris)NRGN
WikiGenes4900
SOURCE (Princeton)NRGN
Genetics Home Reference (NIH)NRGN
Genomic and cartography
GoldenPath hg38 (UCSC)NRGN  -     chr11:124739933-124747206 +  11q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NRGN  -     11q24.2   [Description]    (hg19-Feb_2009)
EnsemblNRGN - 11q24.2 [CytoView hg19]  NRGN - 11q24.2 [CytoView hg38]
Mapping of homologs : NCBINRGN [Mapview hg19]  NRGN [Mapview hg38]
OMIM602350   
Gene and transcription
Genbank (Entrez)BC002835 BM923818 BT007325 DB474181 U89165
RefSeq transcript (Entrez)NM_001126181 NM_006176
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NRGN
Cluster EST : UnigeneHs.524116 [ NCBI ]
CGAP (NCI)Hs.524116
Alternative Splicing GalleryENSG00000154146
Gene ExpressionNRGN [ NCBI-GEO ]   NRGN [ EBI - ARRAY_EXPRESS ]   NRGN [ SEEK ]   NRGN [ MEM ]
Gene Expression Viewer (FireBrowse)NRGN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4900
GTEX Portal (Tissue expression)NRGN
Human Protein AtlasENSG00000154146-NRGN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92686   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92686  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92686
Splice isoforms : SwissVarQ92686
PhosPhoSitePlusQ92686
Domaine pattern : Prosite (Expaxy)IQ (PS50096)   
Domains : Interpro (EBI)IQ_motif_EF-hand-BS   
Domain families : Pfam (Sanger)IQ (PF00612)   
Domain families : Pfam (NCBI)pfam00612   
Domain families : Smart (EMBL)IQ (SM00015)  
Conserved Domain (NCBI)NRGN
DMDM Disease mutations4900
Blocks (Seattle)NRGN
SuperfamilyQ92686
Human Protein Atlas [tissue]ENSG00000154146-NRGN [tissue]
Peptide AtlasQ92686
HPRD03828
IPIIPI00022640   
Protein Interaction databases
DIP (DOE-UCLA)Q92686
IntAct (EBI)Q92686
FunCoupENSG00000154146
BioGRIDNRGN
STRING (EMBL)NRGN
ZODIACNRGN
Ontologies - Pathways
QuickGOQ92686
Ontology : AmiGOcalmodulin binding  phosphatidylinositol-3,4,5-trisphosphate binding  nucleus  signal transduction  nervous system development  associative learning  trans-Golgi network transport vesicle membrane  postsynaptic density  telencephalon development  axon  mitochondrial membrane  neuronal cell body  dendritic spine head  phosphatidic acid binding  positive regulation of long-term synaptic potentiation  
Ontology : EGO-EBIcalmodulin binding  phosphatidylinositol-3,4,5-trisphosphate binding  nucleus  signal transduction  nervous system development  associative learning  trans-Golgi network transport vesicle membrane  postsynaptic density  telencephalon development  axon  mitochondrial membrane  neuronal cell body  dendritic spine head  phosphatidic acid binding  positive regulation of long-term synaptic potentiation  
NDEx NetworkNRGN
Atlas of Cancer Signalling NetworkNRGN
Wikipedia pathwaysNRGN
Orthology - Evolution
OrthoDB4900
GeneTree (enSembl)ENSG00000154146
Phylogenetic Trees/Animal Genes : TreeFamNRGN
HOVERGENQ92686
HOGENOMQ92686
Homologs : HomoloGeneNRGN
Homology/Alignments : Family Browser (UCSC)NRGN
Gene fusions - Rearrangements
Tumor Fusion PortalNRGN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNRGN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NRGN
dbVarNRGN
ClinVarNRGN
1000_GenomesNRGN 
Exome Variant ServerNRGN
ExAC (Exome Aggregation Consortium)ENSG00000154146
GNOMAD BrowserENSG00000154146
Genetic variants : HAPMAP4900
Genomic Variants (DGV)NRGN [DGVbeta]
DECIPHERNRGN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNRGN 
Mutations
ICGC Data PortalNRGN 
TCGA Data PortalNRGN 
Broad Tumor PortalNRGN
OASIS PortalNRGN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNRGN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNRGN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NRGN
DgiDB (Drug Gene Interaction Database)NRGN
DoCM (Curated mutations)NRGN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NRGN (select a term)
intoGenNRGN
Cancer3DNRGN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602350   
Orphanet
DisGeNETNRGN
MedgenNRGN
Genetic Testing Registry NRGN
NextProtQ92686 [Medical]
TSGene4900
GENETestsNRGN
Target ValidationNRGN
Huge Navigator NRGN [HugePedia]
snp3D : Map Gene to Disease4900
BioCentury BCIQNRGN
ClinGenNRGN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4900
Chemical/Pharm GKB GenePA31779
Clinical trialNRGN
Miscellaneous
canSAR (ICR)NRGN (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNRGN
EVEXNRGN
GoPubMedNRGN
iHOPNRGN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:24:16 CET 2017

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