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NRL (neural retina leucine zipper)

Identity

Alias (NCBI)D14S46E
NRL-MAF
RP27
HGNC (Hugo) NRL
HGNC Alias symbD14S46E
RP27
NRL-MAF
LocusID (NCBI) 4901
Atlas_Id 57947
Location 14q11.2  [Link to chromosome band 14q11]
Location_base_pair Starts at 24078700 and ends at 24114949 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACER3 (11q13.5) / NRL (14q11.2)EIF3H (8q23.3) / NRL (14q11.2)LOC100507412 (-) / NRL (14q11.2)
NRL (14q11.2) / NRL (14q11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)NRL   8002
Cards
Entrez_Gene (NCBI)NRL    neural retina leucine zipper
AliasesD14S46E; NRL-MAF; RP27
GeneCards (Weizmann)NRL
Ensembl hg19 (Hinxton)ENSG00000129535 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000129535 [Gene_View]  ENSG00000129535 [Sequence]  chr14:24078700-24114949 [Contig_View]  NRL [Vega]
ICGC DataPortalENSG00000129535
TCGA cBioPortalNRL
AceView (NCBI)NRL
Genatlas (Paris)NRL
SOURCE (Princeton)NRL
Genetics Home Reference (NIH)NRL
Genomic and cartography
GoldenPath hg38 (UCSC)NRL  -     chr14:24078700-24114949 -  14q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NRL  -     14q11.2   [Description]    (hg19-Feb_2009)
GoldenPathNRL - 14q11.2 [CytoView hg19]  NRL - 14q11.2 [CytoView hg38]
ImmunoBaseENSG00000129535
Genome Data Viewer NCBINRL [Mapview hg19]  
OMIM162080   613750   
Gene and transcription
Genbank (Entrez)AB593101 AB593102 AB593103 AB593104 AB593105
RefSeq transcript (Entrez)NM_001354768 NM_001354769 NM_001354770 NM_006177
Consensus coding sequences : CCDS (NCBI)NRL
Gene ExpressionNRL [ NCBI-GEO ]   NRL [ EBI - ARRAY_EXPRESS ]   NRL [ SEEK ]   NRL [ MEM ]
Gene Expression Viewer (FireBrowse)NRL [ Firebrowse - Broad ]
GenevisibleExpression of NRL in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4901
GTEX Portal (Tissue expression)NRL
Human Protein AtlasENSG00000129535-NRL [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP54845   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP54845  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP54845
PhosPhoSitePlusP54845
Domaine pattern : Prosite (Expaxy)BZIP (PS50217)   
Domains : Interpro (EBI)bZIP    bZIP_Maf    Maf_TF_N    Nrl    TF_DNA-bd_sf    Transcription_factor_Maf_fam   
Domain families : Pfam (Sanger)bZIP_Maf (PF03131)    Maf_N (PF08383)   
Domain families : Pfam (NCBI)pfam03131    pfam08383   
Domain families : Smart (EMBL)BRLZ (SM00338)  
Conserved Domain (NCBI)NRL
SuperfamilyP54845
AlphaFold pdb e-kbP54845   
Human Protein Atlas [tissue]ENSG00000129535-NRL [tissue]
Protein Interaction databases
DIP (DOE-UCLA)P54845
IntAct (EBI)P54845
BioGRIDNRL
STRING (EMBL)NRL
ZODIACNRL
Ontologies - Pathways
QuickGOP54845
Ontology : AmiGOchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  protein binding  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  regulation of transcription by RNA polymerase II  visual perception  positive regulation of gene expression  leucine zipper domain binding  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  retinal rod cell development  response to stimulus  sequence-specific double-stranded DNA binding  promoter-specific chromatin binding  
Ontology : EGO-EBIchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  protein binding  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  regulation of transcription by RNA polymerase II  visual perception  positive regulation of gene expression  leucine zipper domain binding  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  retinal rod cell development  response to stimulus  sequence-specific double-stranded DNA binding  promoter-specific chromatin binding  
NDEx NetworkNRL
Atlas of Cancer Signalling NetworkNRL
Wikipedia pathwaysNRL
Orthology - Evolution
OrthoDB4901
GeneTree (enSembl)ENSG00000129535
Phylogenetic Trees/Animal Genes : TreeFamNRL
Homologs : HomoloGeneNRL
Homology/Alignments : Family Browser (UCSC)NRL
Gene fusions - Rearrangements
Fusion : QuiverNRL
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNRL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NRL
dbVarNRL
ClinVarNRL
MonarchNRL
1000_GenomesNRL 
Exome Variant ServerNRL
GNOMAD BrowserENSG00000129535
Varsome BrowserNRL
ACMGNRL variants
VarityP54845
Genomic Variants (DGV)NRL [DGVbeta]
DECIPHERNRL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNRL 
Mutations
ICGC Data PortalNRL 
TCGA Data PortalNRL 
Broad Tumor PortalNRL
OASIS PortalNRL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNRL  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNRL
Mutations and Diseases : HGMDNRL
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNRL
DgiDB (Drug Gene Interaction Database)NRL
DoCM (Curated mutations)NRL
CIViC (Clinical Interpretations of Variants in Cancer)NRL
Cancer3DNRL
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM162080    613750   
Orphanet
DisGeNETNRL
MedgenNRL
Genetic Testing Registry NRL
NextProtP54845 [Medical]
GENETestsNRL
Target ValidationNRL
Huge Navigator NRL [HugePedia]
ClinGenNRL
Clinical trials, drugs, therapy
MyCancerGenomeNRL
Protein Interactions : CTDNRL
Pharm GKB GenePA31781
Pharm GKB PathwaysPA165985892   
PharosP54845
Clinical trialNRL
Miscellaneous
canSAR (ICR)NRL
HarmonizomeNRL
DataMed IndexNRL
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNRL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:23:19 CEST 2021

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