NRP1 (neuropilin 1)

Identity

Other names	BDCA4
	CD304
	DKFZp686A03134
	DKFZp781F1414
	NP1
	NRP
	VEGF165R
HGNC	NRP1
Location	10p12
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	NRP1   8004
Entrez_Gene	NRP1  8829  neuropilin 1
	Cards
GeneCards	NRP1
Ensembl	NRP1 [Search_View]   ENSG00000099250 [Gene_View]
Genatlas	NRP1
GeneLynx	NRP1
eGenome	NRP1
euGene	8829
	Genomic and cartography
GoldenPath	NRP1  -  10p12   chr10:33526553-33663839 -  10p11.22   [Description]    (hg18-March_2006)
Ensembl	NRP1 - 10p11.22 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	NRP1
	Gene and transcription
Genbank	AA973607 [ ENTREZ ]
Genbank	AB209641 [ ENTREZ ]
Genbank	AF016050 [ ENTREZ ]
Genbank	AF018956 [ ENTREZ ]
Genbank	AF086016 [ ENTREZ ]
RefSeq	NM_001024628 [ SRS ]    NM_001024628 [ ENTREZ ]
RefSeq	NM_001024629 [ SRS ]    NM_001024629 [ ENTREZ ]
RefSeq	NM_003873 [ SRS ]    NM_003873 [ ENTREZ ]
RefSeq	AC_000053 [ SRS ]    AC_000053 [ ENTREZ ]
RefSeq	AC_000142 [ SRS ]    AC_000142 [ ENTREZ ]
RefSeq	NC_000010 [ SRS ]    NC_000010 [ ENTREZ ]
RefSeq	NT_008705 [ SRS ]    NT_008705 [ ENTREZ ]
RefSeq	NW_001837932 [ SRS ]    NW_001837932 [ ENTREZ ]
RefSeq	NW_924584 [ SRS ]    NW_924584 [ ENTREZ ]
AceView	NRP1 AceView - NCBI
Unigene	Hs.714624 [ SRS ]    Hs.714624 [ NCBI ]     HS714624 [ spliceNest ]
Fast-db	8260 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O14786 [ SRS]    O14786 [ EXPASY ]     O14786 [ INTERPRO ]     O14786 [ UNIPROT ]
Prosite	PS01180 CUB [ SRS ]    PS01180 CUB [ Expasy ]
Prosite	PS01285 FA58C_1 [ SRS ]    PS01285 FA58C_1 [ Expasy ]
Prosite	PS01286 FA58C_2 [ SRS ]    PS01286 FA58C_2 [ Expasy ]
Prosite	PS50022 FA58C_3 [ SRS ]    PS50022 FA58C_3 [ Expasy ]
Prosite	PS00740 MAM_1 [ SRS ]    PS00740 MAM_1 [ Expasy ]
Prosite	PS50060 MAM_2 [ SRS ]    PS50060 MAM_2 [ Expasy ]
Interpro	IPR000421 Coagulation_factor_5/8-type_C [ SRS ]    IPR000421 Coagulation_factor_5/8-type_C [ EBI ]
Interpro	IPR000859 CUB [ SRS ]    IPR000859 CUB [ EBI ]
Interpro	IPR000998 MAM [ SRS ]    IPR000998 MAM [ EBI ]
Interpro	IPR014648 Neuropilin [ SRS ]    IPR014648 Neuropilin [ EBI ]
CluSTr	O14786
Pfam	PF00431 CUB [ SRS ]    PF00431 CUB [ Sanger ]    pfam00431 [ NCBI-CDD ]
Pfam	PF00754 F5_F8_type_C [ SRS ]    PF00754 F5_F8_type_C [ Sanger ]    pfam00754 [ NCBI-CDD ]
Pfam	PF00629 MAM [ SRS ]    PF00629 MAM [ Sanger ]    pfam00629 [ NCBI-CDD ]
Smart	SM00042 CUB [EMBL]
Smart	SM00231 FA58C [EMBL]
Smart	SM00137 MAM [EMBL]
Blocks	O14786
PDB	1KEX [ SRS ]    1KEX [ PdbSum ],   1KEX [ IMB ]   1KEX [ RSDB ]
PDB	2QQI [ SRS ]    2QQI [ PdbSum ],   2QQI [ IMB ]   2QQI [ RSDB ]
PDB	2QQM [ SRS ]    2QQM [ PdbSum ],   2QQM [ IMB ]   2QQM [ RSDB ]
PDB	2QQN [ SRS ]    2QQN [ PdbSum ],   2QQN [ IMB ]   2QQN [ RSDB ]
HPRD	03642
	Protein Interaction databases
DIP	O14786
IntAct	O14786
	Polymorphism : SNP, mutations, diseases
OMIM	602069    [ map ]
GENECLINICS	602069
SNP	NRP1 [dbSNP-NCBI]
SNP	NM_001024628 [SNP-NCI]
SNP	NM_001024629 [SNP-NCI]
SNP	NM_003873 [SNP-NCI]
SNP	NRP1 [GeneSNPs - Utah]  NRP1] [HGBASE - SRS]
HAPMAP	NRP1 [HAPMAP]
HGMD	NRP1
	General knowledge
Family Browser	NRP1 [UCSC Family Browser]
SOURCE	NM_001024628
SOURCE	NM_001024629
SOURCE	NM_003873
SMD	Hs.714624
SAGE	Hs.714624
GO	angiogenesis [Amigo]  angiogenesis
GO	receptor activity [Amigo]  receptor activity
GO	vascular endothelial growth factor receptor activity [Amigo]  vascular endothelial growth factor receptor activity
GO	protein binding [Amigo]  protein binding
GO	extracellular region [Amigo]  extracellular region
GO	endoplasmic reticulum [Amigo]  endoplasmic reticulum
GO	plasma membrane [Amigo]  plasma membrane
GO	cell adhesion [Amigo]  cell adhesion
GO	signal transduction [Amigo]  signal transduction
GO	cell-cell signaling [Amigo]  cell-cell signaling
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	nervous system development [Amigo]  nervous system development
GO	axon guidance [Amigo]  axon guidance
GO	positive regulation of cell proliferation [Amigo]  positive regulation of cell proliferation
GO	organ morphogenesis [Amigo]  organ morphogenesis
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	cell differentiation [Amigo]  cell differentiation
KEGG	Axon guidance
PubGene	NRP1
TreeFam	NRP1
CTD	8829 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	NRP1 Related clones (RZPD - Berlin)
	PubMed
PubMed	76 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:22:46 2008