Atlas of Genetics and Cytogenetics in Oncology and Haematology

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NRSN1 (neurensin 1)

Identity

Alias_namesVMP
vesicular membrane protein p24
Alias_symbol (synonym)p24
Other alias
HGNC (Hugo) NRSN1
LocusID (NCBI) 140767
Atlas_Id 50176
Location 6p22.3  [Link to chromosome band 6p22]
Location_base_pair Starts at 24126186 and ends at 24147529 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SLC22A23 (6p25.2) / NRSN1 (6p22.3)SLC22A23 6p25.2 / NRSN1 6p22.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p22;p25) SLC22A23/NRSN1

External links

Nomenclature
HGNC (Hugo)NRSN1   17881
Cards
Entrez_Gene (NCBI)NRSN1  140767  neurensin 1
AliasesVMP; p24
GeneCards (Weizmann)NRSN1
Ensembl hg19 (Hinxton)ENSG00000152954 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000152954 [Gene_View]  ENSG00000152954 [Sequence]  chr6:24126186-24147529 [Contig_View]  NRSN1 [Vega]
ICGC DataPortalENSG00000152954
TCGA cBioPortalNRSN1
AceView (NCBI)NRSN1
Genatlas (Paris)NRSN1
WikiGenes140767
SOURCE (Princeton)NRSN1
Genetics Home Reference (NIH)NRSN1
Genomic and cartography
GoldenPath hg38 (UCSC)NRSN1  -     chr6:24126186-24147529 +  6p22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NRSN1  -     6p22.3   [Description]    (hg19-Feb_2009)
GoldenPathNRSN1 - 6p22.3 [CytoView hg19]  NRSN1 - 6p22.3 [CytoView hg38]
ImmunoBaseENSG00000152954
Mapping of homologs : NCBINRSN1 [Mapview hg19]  NRSN1 [Mapview hg38]
OMIM616630   
Gene and transcription
Genbank (Entrez)AF418980 AK096290 AK225775 AK311178 AK314373
RefSeq transcript (Entrez)NM_080723
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NRSN1
Cluster EST : UnigeneHs.726270 [ NCBI ]
CGAP (NCI)Hs.726270
Alternative Splicing GalleryENSG00000152954
Gene ExpressionNRSN1 [ NCBI-GEO ]   NRSN1 [ EBI - ARRAY_EXPRESS ]   NRSN1 [ SEEK ]   NRSN1 [ MEM ]
Gene Expression Viewer (FireBrowse)NRSN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)140767
GTEX Portal (Tissue expression)NRSN1
Human Protein AtlasENSG00000152954-NRSN1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IZ57   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IZ57  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IZ57
Splice isoforms : SwissVarQ8IZ57
PhosPhoSitePlusQ8IZ57
Domains : Interpro (EBI)Neurensin    Nrsn1   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)NRSN1
DMDM Disease mutations140767
Blocks (Seattle)NRSN1
SuperfamilyQ8IZ57
Human Protein Atlas [tissue]ENSG00000152954-NRSN1 [tissue]
Peptide AtlasQ8IZ57
HPRD18285
IPIIPI00293615   IPI00478669   IPI00646123   
Protein Interaction databases
DIP (DOE-UCLA)Q8IZ57
IntAct (EBI)Q8IZ57
FunCoupENSG00000152954
BioGRIDNRSN1
STRING (EMBL)NRSN1
ZODIACNRSN1
Ontologies - Pathways
QuickGOQ8IZ57
Ontology : AmiGOprotein binding  nervous system development  nervous system development  integral component of membrane  transport vesicle  transport vesicle  growth cone  cytoplasmic vesicle  cytoplasmic vesicle  neuron projection  neuron projection  neuronal cell body  neuronal cell body  
Ontology : EGO-EBIprotein binding  nervous system development  nervous system development  integral component of membrane  transport vesicle  transport vesicle  growth cone  cytoplasmic vesicle  cytoplasmic vesicle  neuron projection  neuron projection  neuronal cell body  neuronal cell body  
NDEx NetworkNRSN1
Atlas of Cancer Signalling NetworkNRSN1
Wikipedia pathwaysNRSN1
Orthology - Evolution
OrthoDB140767
GeneTree (enSembl)ENSG00000152954
Phylogenetic Trees/Animal Genes : TreeFamNRSN1
HOGENOMQ8IZ57
Homologs : HomoloGeneNRSN1
Homology/Alignments : Family Browser (UCSC)NRSN1
Gene fusions - Rearrangements
Fusion : MitelmanSLC22A23/NRSN1 [6p25.2/6p22.3]  [t(6;6)(p22;p25)]  
Fusion PortalSLC22A23 6p25.2 NRSN1 6p22.3 PRAD
Fusion : QuiverNRSN1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNRSN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NRSN1
dbVarNRSN1
ClinVarNRSN1
1000_GenomesNRSN1 
Exome Variant ServerNRSN1
ExAC (Exome Aggregation Consortium)ENSG00000152954
GNOMAD BrowserENSG00000152954
Varsome BrowserNRSN1
Genetic variants : HAPMAP140767
Genomic Variants (DGV)NRSN1 [DGVbeta]
DECIPHERNRSN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNRSN1 
Mutations
ICGC Data PortalNRSN1 
TCGA Data PortalNRSN1 
Broad Tumor PortalNRSN1
OASIS PortalNRSN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNRSN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNRSN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NRSN1
DgiDB (Drug Gene Interaction Database)NRSN1
DoCM (Curated mutations)NRSN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NRSN1 (select a term)
intoGenNRSN1
Cancer3DNRSN1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616630   
Orphanet
DisGeNETNRSN1
MedgenNRSN1
Genetic Testing Registry NRSN1
NextProtQ8IZ57 [Medical]
TSGene140767
GENETestsNRSN1
Target ValidationNRSN1
Huge Navigator NRSN1 [HugePedia]
snp3D : Map Gene to Disease140767
BioCentury BCIQNRSN1
ClinGenNRSN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD140767
Chemical/Pharm GKB GenePA38254
Clinical trialNRSN1
Miscellaneous
canSAR (ICR)NRSN1 (select the gene name)
DataMed IndexNRSN1
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNRSN1
EVEXNRSN1
GoPubMedNRSN1
iHOPNRSN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 7 18:11:36 CEST 2019
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