Atlas of Genetics and Cytogenetics in Oncology and Haematology


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NSMCE3 (NSE3 homolog, SMC5-SMC6 complex component)

Identity

Alias_namesNDNL2
necdin-like 2
necdin-like 2, SMC5-SMC6 complex component
Alias_symbol (synonym)HCA4
MAGEG1
MAGEL3
NSE3
Other aliasLICS
HGNC (Hugo) NSMCE3
LocusID (NCBI) 56160
Atlas_Id 55529
Location 15q13.1  [Link to chromosome band 15q13]
Location_base_pair Starts at 29268149 and ends at 29269816 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NSMCE3   7677
Cards
Entrez_Gene (NCBI)NSMCE3  56160  NSE3 homolog, SMC5-SMC6 complex component
AliasesHCA4; LICS; MAGEG1; MAGEL3; 
NDNL2; NSE3
GeneCards (Weizmann)NSMCE3
Ensembl hg19 (Hinxton)ENSG00000185115 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185115 [Gene_View]  chr15:29268149-29269816 [Contig_View]  NSMCE3 [Vega]
ICGC DataPortalENSG00000185115
TCGA cBioPortalNSMCE3
AceView (NCBI)NSMCE3
Genatlas (Paris)NSMCE3
WikiGenes56160
SOURCE (Princeton)NSMCE3
Genetics Home Reference (NIH)NSMCE3
Genomic and cartography
GoldenPath hg38 (UCSC)NSMCE3  -     chr15:29268149-29269816 -  15q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NSMCE3  -     15q13.1   [Description]    (hg19-Feb_2009)
EnsemblNSMCE3 - 15q13.1 [CytoView hg19]  NSMCE3 - 15q13.1 [CytoView hg38]
Mapping of homologs : NCBINSMCE3 [Mapview hg19]  NSMCE3 [Mapview hg38]
OMIM608243   617241   
Gene and transcription
Genbank (Entrez)AF490510 AK056957 AK074138 AU310582 BC035458
RefSeq transcript (Entrez)NM_138704
RefSeq genomic (Entrez)NC_000015 NC_018926 NG_053143 NT_187660 NW_011332701
Consensus coding sequences : CCDS (NCBI)NSMCE3
Cluster EST : UnigeneHs.94011 [ NCBI ]
CGAP (NCI)Hs.94011
Alternative Splicing GalleryENSG00000185115
Gene ExpressionNSMCE3 [ NCBI-GEO ]   NSMCE3 [ EBI - ARRAY_EXPRESS ]   NSMCE3 [ SEEK ]   NSMCE3 [ MEM ]
Gene Expression Viewer (FireBrowse)NSMCE3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56160
GTEX Portal (Tissue expression)NSMCE3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96MG7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96MG7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96MG7
Splice isoforms : SwissVarQ96MG7
PhosPhoSitePlusQ96MG7
Domaine pattern : Prosite (Expaxy)MAGE (PS50838)   
Domains : Interpro (EBI)MHD_dom   
Domain families : Pfam (Sanger)MAGE (PF01454)   
Domain families : Pfam (NCBI)pfam01454   
Domain families : Smart (EMBL)MAGE (SM01373)  
Conserved Domain (NCBI)NSMCE3
DMDM Disease mutations56160
Blocks (Seattle)NSMCE3
PDB (SRS)3NW0    5HVQ   
PDB (PDBSum)3NW0    5HVQ   
PDB (IMB)3NW0    5HVQ   
PDB (RSDB)3NW0    5HVQ   
Structural Biology KnowledgeBase3NW0    5HVQ   
SCOP (Structural Classification of Proteins)3NW0    5HVQ   
CATH (Classification of proteins structures)3NW0    5HVQ   
SuperfamilyQ96MG7
Human Protein AtlasENSG00000185115
Peptide AtlasQ96MG7
HPRD10503
IPIIPI00217104   
Protein Interaction databases
DIP (DOE-UCLA)Q96MG7
IntAct (EBI)Q96MG7
FunCoupENSG00000185115
BioGRIDNSMCE3
STRING (EMBL)NSMCE3
ZODIACNSMCE3
Ontologies - Pathways
QuickGOQ96MG7
Ontology : AmiGOchromosome, telomeric region  protein binding  nucleoplasm  cytoplasm  DNA repair  DNA recombination  Smc5-Smc6 complex  positive regulation of protein ubiquitination  cellular response to UV  regulation of growth  protein dimerization activity  cellular response to radiation  cellular response to hydroxyurea  
Ontology : EGO-EBIchromosome, telomeric region  protein binding  nucleoplasm  cytoplasm  DNA repair  DNA recombination  Smc5-Smc6 complex  positive regulation of protein ubiquitination  cellular response to UV  regulation of growth  protein dimerization activity  cellular response to radiation  cellular response to hydroxyurea  
NDEx NetworkNSMCE3
Atlas of Cancer Signalling NetworkNSMCE3
Wikipedia pathwaysNSMCE3
Orthology - Evolution
OrthoDB56160
GeneTree (enSembl)ENSG00000185115
Phylogenetic Trees/Animal Genes : TreeFamNSMCE3
HOVERGENQ96MG7
HOGENOMQ96MG7
Homologs : HomoloGeneNSMCE3
Homology/Alignments : Family Browser (UCSC)NSMCE3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNSMCE3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NSMCE3
dbVarNSMCE3
ClinVarNSMCE3
1000_GenomesNSMCE3 
Exome Variant ServerNSMCE3
ExAC (Exome Aggregation Consortium)NSMCE3 (select the gene name)
Genetic variants : HAPMAP56160
Genomic Variants (DGV)NSMCE3 [DGVbeta]
DECIPHERNSMCE3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNSMCE3 
Mutations
ICGC Data PortalNSMCE3 
TCGA Data PortalNSMCE3 
Broad Tumor PortalNSMCE3
OASIS PortalNSMCE3 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDNSMCE3
BioMutasearch NSMCE3
DgiDB (Drug Gene Interaction Database)NSMCE3
DoCM (Curated mutations)NSMCE3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NSMCE3 (select a term)
intoGenNSMCE3
Cancer3DNSMCE3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608243    617241   
Orphanet
MedgenNSMCE3
Genetic Testing Registry NSMCE3
NextProtQ96MG7 [Medical]
TSGene56160
GENETestsNSMCE3
Target ValidationNSMCE3
Huge Navigator NSMCE3 [HugePedia]
snp3D : Map Gene to Disease56160
BioCentury BCIQNSMCE3
ClinGenNSMCE3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56160
Chemical/Pharm GKB GenePA31480
Clinical trialNSMCE3
Miscellaneous
canSAR (ICR)NSMCE3 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNSMCE3
EVEXNSMCE3
GoPubMedNSMCE3
iHOPNSMCE3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:09:29 CEST 2017

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