NSMCE4A (NSE4 homolog A, SMC5-SMC6 complex component)

2012-06-01  

Identity

HGNC
LOCATION
10q26.13
LOCUSID
ALIAS
C10orf86,NS4EA,NSE4A
FUSION GENES

Other Information

Locus ID:

NCBI: 54780
MIM: 612987
HGNC: 25935
Ensembl: ENSG00000107672

Variants:

dbSNP: 54780
ClinVar: 54780
TCGA: ENSG00000107672
COSMIC: NSMCE4A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000107672ENST00000369017Q9NXX6
ENSG00000107672ENST00000369023Q9NXX6

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
SUMOylationREACTOMER-HSA-2990846
SUMO E3 ligases SUMOylate target proteinsREACTOMER-HSA-3108232
SUMOylation of DNA damage response and repair proteinsREACTOMER-HSA-3108214

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
255909992015The melanoma-associated antigen 1 (MAGEA1) protein stimulates the E3 ubiquitin-ligase activity of TRIM31 within a TRIM31-MAGEA1-NSE4 complex.15

Citation

Dessen P

NSMCE4A (NSE4 homolog A, SMC5-SMC6 complex component)

Atlas Genet Cytogenet Oncol Haematol. 2012-06-01

Online version: http://atlasgeneticsoncology.org/gene/52754/nsmce4a