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NT5M (5',3'-nucleotidase, mitochondrial)

Identity

Alias_names5' nucleotidase, mitochondrial
Alias_symbol (synonym)dNT-2
dNT2
mdN
Other alias
HGNC (Hugo) NT5M
LocusID (NCBI) 56953
Atlas_Id 71003
Location 17p11.2  [Link to chromosome band 17p11]
Location_base_pair Starts at 17303366 and ends at 17347663 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NT5M   15769
Cards
Entrez_Gene (NCBI)NT5M  56953  5',3'-nucleotidase, mitochondrial
AliasesdNT-2; dNT2; mdN
GeneCards (Weizmann)NT5M
Ensembl hg19 (Hinxton)ENSG00000205309 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000205309 [Gene_View]  chr17:17303366-17347663 [Contig_View]  NT5M [Vega]
ICGC DataPortalENSG00000205309
TCGA cBioPortalNT5M
AceView (NCBI)NT5M
Genatlas (Paris)NT5M
WikiGenes56953
SOURCE (Princeton)NT5M
Genetics Home Reference (NIH)NT5M
Genomic and cartography
GoldenPath hg38 (UCSC)NT5M  -     chr17:17303366-17347663 +  17p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NT5M  -     17p11.2   [Description]    (hg19-Feb_2009)
EnsemblNT5M - 17p11.2 [CytoView hg19]  NT5M - 17p11.2 [CytoView hg38]
Mapping of homologs : NCBINT5M [Mapview hg19]  NT5M [Mapview hg38]
OMIM605292   
Gene and transcription
Genbank (Entrez)AF210652 AL526346 BC035838 DQ323995
RefSeq transcript (Entrez)NM_020201
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NT5M
Cluster EST : UnigeneHs.513977 [ NCBI ]
CGAP (NCI)Hs.513977
Alternative Splicing GalleryENSG00000205309
Gene ExpressionNT5M [ NCBI-GEO ]   NT5M [ EBI - ARRAY_EXPRESS ]   NT5M [ SEEK ]   NT5M [ MEM ]
Gene Expression Viewer (FireBrowse)NT5M [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56953
GTEX Portal (Tissue expression)NT5M
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NPB1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NPB1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NPB1
Splice isoforms : SwissVarQ9NPB1
Catalytic activity : Enzyme3.1.3.- [ Enzyme-Expasy ]   3.1.3.-3.1.3.- [ IntEnz-EBI ]   3.1.3.- [ BRENDA ]   3.1.3.- [ KEGG ]   
PhosPhoSitePlusQ9NPB1
Domains : Interpro (EBI)5'(3')-deoxyribonucleotidase    HAD-like_dom   
Domain families : Pfam (Sanger)NT5C (PF06941)   
Domain families : Pfam (NCBI)pfam06941   
Conserved Domain (NCBI)NT5M
DMDM Disease mutations56953
Blocks (Seattle)NT5M
PDB (SRS)1MH9    1Q91    1Q92    1Z4I    1Z4J    1Z4K    1Z4L    1Z4M    1Z4P    1Z4Q    2JAU    2JAW    4L6A    4L6C    4MUM    4MWO    4NFL    4YIK   
PDB (PDBSum)1MH9    1Q91    1Q92    1Z4I    1Z4J    1Z4K    1Z4L    1Z4M    1Z4P    1Z4Q    2JAU    2JAW    4L6A    4L6C    4MUM    4MWO    4NFL    4YIK   
PDB (IMB)1MH9    1Q91    1Q92    1Z4I    1Z4J    1Z4K    1Z4L    1Z4M    1Z4P    1Z4Q    2JAU    2JAW    4L6A    4L6C    4MUM    4MWO    4NFL    4YIK   
PDB (RSDB)1MH9    1Q91    1Q92    1Z4I    1Z4J    1Z4K    1Z4L    1Z4M    1Z4P    1Z4Q    2JAU    2JAW    4L6A    4L6C    4MUM    4MWO    4NFL    4YIK   
Structural Biology KnowledgeBase1MH9    1Q91    1Q92    1Z4I    1Z4J    1Z4K    1Z4L    1Z4M    1Z4P    1Z4Q    2JAU    2JAW    4L6A    4L6C    4MUM    4MWO    4NFL    4YIK   
SCOP (Structural Classification of Proteins)1MH9    1Q91    1Q92    1Z4I    1Z4J    1Z4K    1Z4L    1Z4M    1Z4P    1Z4Q    2JAU    2JAW    4L6A    4L6C    4MUM    4MWO    4NFL    4YIK   
CATH (Classification of proteins structures)1MH9    1Q91    1Q92    1Z4I    1Z4J    1Z4K    1Z4L    1Z4M    1Z4P    1Z4Q    2JAU    2JAW    4L6A    4L6C    4MUM    4MWO    4NFL    4YIK   
SuperfamilyQ9NPB1
Human Protein AtlasENSG00000205309
Peptide AtlasQ9NPB1
HPRD12009
IPIIPI00791272   
Protein Interaction databases
DIP (DOE-UCLA)Q9NPB1
IntAct (EBI)Q9NPB1
FunCoupENSG00000205309
BioGRIDNT5M
STRING (EMBL)NT5M
ZODIACNT5M
Ontologies - Pathways
QuickGOQ9NPB1
Ontology : AmiGOnucleotide binding  mitochondrion  mitochondrial matrix  DNA replication  nucleotidase activity  5'-nucleotidase activity  pyrimidine deoxyribonucleotide catabolic process  dephosphorylation  dUMP catabolic process  pyrimidine nucleoside catabolic process  metal ion binding  
Ontology : EGO-EBInucleotide binding  mitochondrion  mitochondrial matrix  DNA replication  nucleotidase activity  5'-nucleotidase activity  pyrimidine deoxyribonucleotide catabolic process  dephosphorylation  dUMP catabolic process  pyrimidine nucleoside catabolic process  metal ion binding  
Pathways : KEGGPurine metabolism    Pyrimidine metabolism    Nicotinate and nicotinamide metabolism   
NDEx NetworkNT5M
Atlas of Cancer Signalling NetworkNT5M
Wikipedia pathwaysNT5M
Orthology - Evolution
OrthoDB56953
GeneTree (enSembl)ENSG00000205309
Phylogenetic Trees/Animal Genes : TreeFamNT5M
HOVERGENQ9NPB1
HOGENOMQ9NPB1
Homologs : HomoloGeneNT5M
Homology/Alignments : Family Browser (UCSC)NT5M
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNT5M [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NT5M
dbVarNT5M
ClinVarNT5M
1000_GenomesNT5M 
Exome Variant ServerNT5M
ExAC (Exome Aggregation Consortium)NT5M (select the gene name)
Genetic variants : HAPMAP56953
Genomic Variants (DGV)NT5M [DGVbeta]
DECIPHERNT5M [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNT5M 
Mutations
ICGC Data PortalNT5M 
TCGA Data PortalNT5M 
Broad Tumor PortalNT5M
OASIS PortalNT5M [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNT5M  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNT5M
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NT5M
DgiDB (Drug Gene Interaction Database)NT5M
DoCM (Curated mutations)NT5M (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NT5M (select a term)
intoGenNT5M
Cancer3DNT5M(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605292   
Orphanet
MedgenNT5M
Genetic Testing Registry NT5M
NextProtQ9NPB1 [Medical]
TSGene56953
GENETestsNT5M
Target ValidationNT5M
Huge Navigator NT5M [HugePedia]
snp3D : Map Gene to Disease56953
BioCentury BCIQNT5M
ClinGenNT5M
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56953
Chemical/Pharm GKB GenePA31805
Clinical trialNT5M
Miscellaneous
canSAR (ICR)NT5M (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNT5M
EVEXNT5M
GoPubMedNT5M
iHOPNT5M
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:32:24 CEST 2017

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