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NTF4 (neurotrophin 4)

Identity

Alias_namesNTF5
neurotrophin 5 (neurotrophin 4/5)
Alias_symbol (synonym)NT-4/5
GLC1O
Other aliasGLC10
NT-4
NT-5
NT4
NT5
HGNC (Hugo) NTF4
LocusID (NCBI) 4909
Atlas_Id 50016
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 49061140 and ends at 49063867 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NTF4   8024
Cards
Entrez_Gene (NCBI)NTF4  4909  neurotrophin 4
AliasesGLC10; GLC1O; NT-4; NT-4/5; 
NT-5; NT4; NT5; NTF5
GeneCards (Weizmann)NTF4
Ensembl hg19 (Hinxton)ENSG00000225950 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000225950 [Gene_View]  chr19:49061140-49063867 [Contig_View]  NTF4 [Vega]
ICGC DataPortalENSG00000225950
TCGA cBioPortalNTF4
AceView (NCBI)NTF4
Genatlas (Paris)NTF4
WikiGenes4909
SOURCE (Princeton)NTF4
Genetics Home Reference (NIH)NTF4
Genomic and cartography
GoldenPath hg38 (UCSC)NTF4  -     chr19:49061140-49063867 -  19q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NTF4  -     19q13.33   [Description]    (hg19-Feb_2009)
EnsemblNTF4 - 19q13.33 [CytoView hg19]  NTF4 - 19q13.33 [CytoView hg38]
Mapping of homologs : NCBINTF4 [Mapview hg19]  NTF4 [Mapview hg38]
OMIM162662   613100   
Gene and transcription
Genbank (Entrez)AK297906 BC012421 BT019368 BT019369 CR541900
RefSeq transcript (Entrez)NM_006179
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NTF4
Cluster EST : UnigeneHs.743915 [ NCBI ]
CGAP (NCI)Hs.743915
Alternative Splicing GalleryENSG00000225950
Gene ExpressionNTF4 [ NCBI-GEO ]   NTF4 [ EBI - ARRAY_EXPRESS ]   NTF4 [ SEEK ]   NTF4 [ MEM ]
Gene Expression Viewer (FireBrowse)NTF4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4909
GTEX Portal (Tissue expression)NTF4
Human Protein AtlasENSG00000225950-NTF4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP34130   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP34130  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP34130
Splice isoforms : SwissVarP34130
PhosPhoSitePlusP34130
Domaine pattern : Prosite (Expaxy)NGF_1 (PS00248)    NGF_2 (PS50270)   
Domains : Interpro (EBI)Cystine-knot_cytokine    Nerve_growth_factor-like    Nerve_growth_factor-rel    Nerve_growth_factor_CS    Neurotrophin-4   
Domain families : Pfam (Sanger)NGF (PF00243)   
Domain families : Pfam (NCBI)pfam00243   
Domain families : Smart (EMBL)NGF (SM00140)  
Domain structure : Prodom (Prabi Lyon)Nerve_growth_factor-rel (PD002052)   
Conserved Domain (NCBI)NTF4
DMDM Disease mutations4909
Blocks (Seattle)NTF4
PDB (SRS)1B8M    1B98    1HCF   
PDB (PDBSum)1B8M    1B98    1HCF   
PDB (IMB)1B8M    1B98    1HCF   
PDB (RSDB)1B8M    1B98    1HCF   
Structural Biology KnowledgeBase1B8M    1B98    1HCF   
SCOP (Structural Classification of Proteins)1B8M    1B98    1HCF   
CATH (Classification of proteins structures)1B8M    1B98    1HCF   
SuperfamilyP34130
Human Protein Atlas [tissue]ENSG00000225950-NTF4 [tissue]
Peptide AtlasP34130
HPRD01220
IPIIPI00030097   
Protein Interaction databases
DIP (DOE-UCLA)P34130
IntAct (EBI)P34130
FunCoupENSG00000225950
BioGRIDNTF4
STRING (EMBL)NTF4
ZODIACNTF4
Ontologies - Pathways
QuickGOP34130
Ontology : AmiGOneurotrophin p75 receptor binding  protein binding  extracellular region  extracellular region  endoplasmic reticulum lumen  transmembrane receptor protein tyrosine kinase signaling pathway  cell-cell signaling  ganglion mother cell fate determination  long-term memory  sensory organ boundary specification  growth factor activity  adult locomotory behavior  epidermis development  cytoplasmic vesicle  mechanoreceptor differentiation  negative regulation of neuron apoptotic process  regulation of neuron differentiation  neuron projection morphogenesis  innervation  taste bud development  
Ontology : EGO-EBIneurotrophin p75 receptor binding  protein binding  extracellular region  extracellular region  endoplasmic reticulum lumen  transmembrane receptor protein tyrosine kinase signaling pathway  cell-cell signaling  ganglion mother cell fate determination  long-term memory  sensory organ boundary specification  growth factor activity  adult locomotory behavior  epidermis development  cytoplasmic vesicle  mechanoreceptor differentiation  negative regulation of neuron apoptotic process  regulation of neuron differentiation  neuron projection morphogenesis  innervation  taste bud development  
Pathways : KEGGMAPK signaling pathway    Neurotrophin signaling pathway   
NDEx NetworkNTF4
Atlas of Cancer Signalling NetworkNTF4
Wikipedia pathwaysNTF4
Orthology - Evolution
OrthoDB4909
GeneTree (enSembl)ENSG00000225950
Phylogenetic Trees/Animal Genes : TreeFamNTF4
HOVERGENP34130
HOGENOMP34130
Homologs : HomoloGeneNTF4
Homology/Alignments : Family Browser (UCSC)NTF4
Gene fusions - Rearrangements
Tumor Fusion PortalNTF4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNTF4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NTF4
dbVarNTF4
ClinVarNTF4
1000_GenomesNTF4 
Exome Variant ServerNTF4
ExAC (Exome Aggregation Consortium)ENSG00000225950
GNOMAD BrowserENSG00000225950
Genetic variants : HAPMAP4909
Genomic Variants (DGV)NTF4 [DGVbeta]
DECIPHERNTF4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNTF4 
Mutations
ICGC Data PortalNTF4 
TCGA Data PortalNTF4 
Broad Tumor PortalNTF4
OASIS PortalNTF4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNTF4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNTF4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NTF4
DgiDB (Drug Gene Interaction Database)NTF4
DoCM (Curated mutations)NTF4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NTF4 (select a term)
intoGenNTF4
Cancer3DNTF4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM162662    613100   
Orphanet
DisGeNETNTF4
MedgenNTF4
Genetic Testing Registry NTF4
NextProtP34130 [Medical]
TSGene4909
GENETestsNTF4
Target ValidationNTF4
Huge Navigator NTF4 [HugePedia]
snp3D : Map Gene to Disease4909
BioCentury BCIQNTF4
ClinGenNTF4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4909
Chemical/Pharm GKB GenePA162398206
Clinical trialNTF4
Miscellaneous
canSAR (ICR)NTF4 (select the gene name)
Probes
Litterature
PubMed57 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNTF4
EVEXNTF4
GoPubMedNTF4
iHOPNTF4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:26:53 CET 2017

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