NTHL1 (nth endonuclease III-like 1 (E. coli))

Identity

Other names	NTH1
	OCTS3
HGNC	NTHL1
Location	16p13.3
Location_base_pair	Starts at 2029817 and ends at 2037868 bp from pter (hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	NTHL1   8028
Entrez_Gene	NTHL1  4913  nth endonuclease III-like 1 (E. coli)
	Cards
GeneCards	NTHL1
Ensembl	NTHL1 [Search_View]   ENSG00000065057 [Gene_View]
Genatlas	NTHL1
GeneLynx	NTHL1
eGenome	NTHL1
euGene	4913
	Genomic and cartography
GoldenPath	NTHL1  -  16p13.3   chr16:2029817-2037868 -  16p13.3   [Description]    (hg18-March_2006)
Ensembl	NTHL1 - 16p13.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	NTHL1
	Gene and transcription
Genbank	AB001575 [ ENTREZ ]
Genbank	BC000391 [ ENTREZ ]
Genbank	BC003014 [ ENTREZ ]
Genbank	CR597616 [ ENTREZ ]
Genbank	CR625882 [ ENTREZ ]
RefSeq	NM_002528 [ SRS ]    NM_002528 [ ENTREZ ]
RefSeq	AC_000059 [ SRS ]    AC_000059 [ ENTREZ ]
RefSeq	AC_000148 [ SRS ]    AC_000148 [ ENTREZ ]
RefSeq	NC_000016 [ SRS ]    NC_000016 [ ENTREZ ]
RefSeq	NG_005895 [ SRS ]    NG_005895 [ ENTREZ ]
RefSeq	NT_037887 [ SRS ]    NT_037887 [ ENTREZ ]
RefSeq	NW_001838339 [ SRS ]    NW_001838339 [ ENTREZ ]
RefSeq	NW_926018 [ SRS ]    NW_926018 [ ENTREZ ]
AceView	NTHL1 AceView - NCBI
Unigene	Hs.66196 [ SRS ]    Hs.66196 [ NCBI ]     HS66196 [ spliceNest ]
Fast-db	1745 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P78549 [ SRS]    P78549 [ EXPASY ]     P78549 [ INTERPRO ]     P78549 [ UNIPROT ]
Prosite	PS00764 ENDONUCLEASE_III_1 [ SRS ]    PS00764 ENDONUCLEASE_III_1 [ Expasy ]
Prosite	PS01155 ENDONUCLEASE_III_2 [ SRS ]    PS01155 ENDONUCLEASE_III_2 [ Expasy ]
Interpro	IPR003265 Endo_3c [ SRS ]    IPR003265 Endo_3c [ EBI ]
Interpro	IPR004036 Endonuclease-III_CS2 [ SRS ]    IPR004036 Endonuclease-III_CS2 [ EBI ]
Interpro	IPR004035 Endouclease-III_FeS-bd_CS1 [ SRS ]    IPR004035 Endouclease-III_FeS-bd_CS1 [ EBI ]
Interpro	IPR003651 FeS_bd [ SRS ]    IPR003651 FeS_bd [ EBI ]
Interpro	IPR000445 HhH [ SRS ]    IPR000445 HhH [ EBI ]
CluSTr	P78549
Pfam	PF00633 HHH [ SRS ]    PF00633 HHH [ Sanger ]    pfam00633 [ NCBI-CDD ]
Pfam	PF00730 HhH-GPD [ SRS ]    PF00730 HhH-GPD [ Sanger ]    pfam00730 [ NCBI-CDD ]
Smart	SM00478 ENDO3c [EMBL]
Smart	SM00525 FES [EMBL]
Blocks	P78549
HPRD	04039
	Protein Interaction databases
DIP	P78549
IntAct	P78549
	Polymorphism : SNP, mutations, diseases
OMIM	602656    [ map ]
GENECLINICS	602656
SNP	NTHL1 [dbSNP-NCBI]
SNP	NM_002528 [SNP-NCI]
SNP	NTHL1 [GeneSNPs - Utah]  NTHL1] [HGBASE - SRS]
HAPMAP	NTHL1 [HAPMAP]
COSMIC	NTHL1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	NTHL1
	General knowledge
Family Browser	NTHL1 [UCSC Family Browser]
SOURCE	NM_002528
SMD	Hs.66196
SAGE	Hs.66196
GO	oxidized pyrimidine base lesion DNA N-glycosylase activity [Amigo]  oxidized pyrimidine base lesion DNA N-glycosylase activity
GO	DNA binding [Amigo]  DNA binding
GO	double-stranded DNA binding [Amigo]  double-stranded DNA binding
GO	endonuclease activity [Amigo]  endonuclease activity
GO	iron ion binding [Amigo]  iron ion binding
GO	protein binding [Amigo]  protein binding
GO	intracellular [Amigo]  intracellular
GO	nucleus [Amigo]  nucleus
GO	nucleoplasm [Amigo]  nucleoplasm
GO	mitochondrion [Amigo]  mitochondrion
GO	nucleotide-excision repair, DNA incision, 5'-to lesion [Amigo]  nucleotide-excision repair, DNA incision, 5'-to lesion
GO	metabolic process [Amigo]  metabolic process
GO	hydrolase activity, acting on glycosyl bonds [Amigo]  hydrolase activity, acting on glycosyl bonds
GO	lyase activity [Amigo]  lyase activity
GO	DNA N-glycosylase activity [Amigo]  DNA N-glycosylase activity
GO	depyrimidination [Amigo]  depyrimidination
GO	metal ion binding [Amigo]  metal ion binding
GO	4 iron, 4 sulfur cluster binding [Amigo]  4 iron, 4 sulfur cluster binding
PubGene	NTHL1
TreeFam	NTHL1
CTD	4913 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	NTHL1 Related clones (RZPD - Berlin)
	PubMed
PubMed	31 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 11 13:23:58 2008