NTNG1 (netrin G1)

2014-08-01  

Identity

HGNC
LOCATION
1p13.3
LOCUSID
ALIAS
Lmnt1
FUSION GENES

Other Information

Locus ID:

NCBI: 22854
MIM: 608818
HGNC: 23319
Ensembl: ENSG00000162631

Variants:

dbSNP: 22854
ClinVar: 22854
TCGA: ENSG00000162631
COSMIC: NTNG1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162631ENST00000370065Q9Y2I2
ENSG00000162631ENST00000370066Q9Y2I2
ENSG00000162631ENST00000370066X5DNW2
ENSG00000162631ENST00000370067Q9Y2I2
ENSG00000162631ENST00000370068Q9Y2I2
ENSG00000162631ENST00000370071Q9Y2I2
ENSG00000162631ENST00000370071X5DNW2
ENSG00000162631ENST00000370073Q9Y2I2
ENSG00000162631ENST00000370074Q9Y2I2

Expression (GTEx)

0
1
2
3
4
5
6
7

Pathways

PathwaySourceExternal ID
Axon guidanceKEGGko04360
Cell adhesion molecules (CAMs)KEGGko04514
Axon guidanceKEGGhsa04360
Cell adhesion molecules (CAMs)KEGGhsa04514
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteinsREACTOMER-HSA-163125

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA448320allopurinolChemicalClinicalAnnotationassociatedPD30924126

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.75
210796072011A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa.67
145954432003The netrin-G1 ligand NGL-1 promotes the outgrowth of thalamocortical axons.65
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
157053542005A family-based association study and gene expression analyses of netrin-G1 and -G2 genes in schizophrenia.30
158708262005Disruption of Netrin G1 by a balanced chromosome translocation in a girl with Rett syndrome.26
175079102008Decreased mRNA expression of netrin-G1 and netrin-G2 in the temporal lobe in schizophrenia and bipolar disorder.22
239864732013Trans-induced cis interaction in the tripartite NGL-1, netrin-G1 and LAR adhesion complex promotes development of excitatory synapses.15
159014892005Human netrin-G1 isoforms show evidence of differential expression.12

Citation

Dessen P

NTNG1 (netrin G1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54513/ntng1