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NTPCR (nucleoside-triphosphatase, cancer-related)

Identity

Alias_namesC1orf57
chromosome 1 open reading frame 57
Alias_symbol (synonym)MGC13186
HCR-NTPase
Other aliasTHEP1
HGNC (Hugo) NTPCR
LocusID (NCBI) 84284
Atlas_Id 51970
Location 1q42.2  [Link to chromosome band 1q42]
Location_base_pair Starts at 232950531 and ends at 232978802 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARID4B (1q42.3) / NTPCR (1q42.2)NTPCR (1q42.2) / ITGA9 (3p22.2)NTPCR (1q42.2) / THAP4 (2q37.3)
PRG2 (11q12.1) / NTPCR (1q42.2)PRIMA1 (14q32.12) / NTPCR (1q42.2)ARID4B 1q42.3 / NTPCR 1q42.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]

Solid Tumors TT_t0101q42q42ID104074

External links

Nomenclature
HGNC (Hugo)NTPCR   28204
Cards
Entrez_Gene (NCBI)NTPCR  84284  nucleoside-triphosphatase, cancer-related
AliasesC1orf57; HCR-NTPase; THEP1
GeneCards (Weizmann)NTPCR
Ensembl hg19 (Hinxton)ENSG00000135778 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135778 [Gene_View]  ENSG00000135778 [Sequence]  chr1:232950531-232978802 [Contig_View]  NTPCR [Vega]
ICGC DataPortalENSG00000135778
TCGA cBioPortalNTPCR
AceView (NCBI)NTPCR
Genatlas (Paris)NTPCR
WikiGenes84284
SOURCE (Princeton)NTPCR
Genetics Home Reference (NIH)NTPCR
Genomic and cartography
GoldenPath hg38 (UCSC)NTPCR  -     chr1:232950531-232978802 +  1q42.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NTPCR  -     1q42.2   [Description]    (hg19-Feb_2009)
GoldenPathNTPCR - 1q42.2 [CytoView hg19]  NTPCR - 1q42.2 [CytoView hg38]
ImmunoBaseENSG00000135778
Mapping of homologs : NCBINTPCR [Mapview hg19]  NTPCR [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA635564 AF416713 AK311229 AK316591 BC005102
RefSeq transcript (Entrez)NM_001329452 NM_001329453 NM_032324
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NTPCR
Cluster EST : UnigeneHs.642715 [ NCBI ]
CGAP (NCI)Hs.642715
Alternative Splicing GalleryENSG00000135778
Gene ExpressionNTPCR [ NCBI-GEO ]   NTPCR [ EBI - ARRAY_EXPRESS ]   NTPCR [ SEEK ]   NTPCR [ MEM ]
Gene Expression Viewer (FireBrowse)NTPCR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84284
GTEX Portal (Tissue expression)NTPCR
Human Protein AtlasENSG00000135778-NTPCR [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BSD7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BSD7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BSD7
Splice isoforms : SwissVarQ9BSD7
Catalytic activity : Enzyme3.6.1.15 [ Enzyme-Expasy ]   3.6.1.153.6.1.15 [ IntEnz-EBI ]   3.6.1.15 [ BRENDA ]   3.6.1.15 [ KEGG ]   
PhosPhoSitePlusQ9BSD7
Domains : Interpro (EBI)AAA+_ATPase    Nuc-triphosphatase_THEP1    P-loop_NTPase   
Domain families : Pfam (Sanger)NTPase_1 (PF03266)   
Domain families : Pfam (NCBI)pfam03266   
Domain families : Smart (EMBL)AAA (SM00382)  
Conserved Domain (NCBI)NTPCR
DMDM Disease mutations84284
Blocks (Seattle)NTPCR
PDB (RSDB)2I3B   
PDB Europe2I3B   
PDB (PDBSum)2I3B   
PDB (IMB)2I3B   
Structural Biology KnowledgeBase2I3B   
SCOP (Structural Classification of Proteins)2I3B   
CATH (Classification of proteins structures)2I3B   
SuperfamilyQ9BSD7
Human Protein Atlas [tissue]ENSG00000135778-NTPCR [tissue]
Peptide AtlasQ9BSD7
HPRD17486
IPIIPI00031570   IPI00514501   
Protein Interaction databases
DIP (DOE-UCLA)Q9BSD7
IntAct (EBI)Q9BSD7
FunCoupENSG00000135778
BioGRIDNTPCR
STRING (EMBL)NTPCR
ZODIACNTPCR
Ontologies - Pathways
QuickGOQ9BSD7
Ontology : AmiGORNA binding  ATP binding  membrane  dephosphorylation  nucleoside-triphosphatase activity  nucleotide phosphatase activity, acting on free nucleotides  
Ontology : EGO-EBIRNA binding  ATP binding  membrane  dephosphorylation  nucleoside-triphosphatase activity  nucleotide phosphatase activity, acting on free nucleotides  
Pathways : KEGGPurine metabolism    Thiamine metabolism   
NDEx NetworkNTPCR
Atlas of Cancer Signalling NetworkNTPCR
Wikipedia pathwaysNTPCR
Orthology - Evolution
OrthoDB84284
GeneTree (enSembl)ENSG00000135778
Phylogenetic Trees/Animal Genes : TreeFamNTPCR
HOGENOMQ9BSD7
Homologs : HomoloGeneNTPCR
Homology/Alignments : Family Browser (UCSC)NTPCR
Gene fusions - Rearrangements
Fusion : MitelmanARID4B/NTPCR [1q42.3/1q42.2]  [t(1;1)(q42;q42)]  
Fusion PortalARID4B 1q42.3 NTPCR 1q42.2 BLCA
Fusion : QuiverNTPCR
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNTPCR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NTPCR
dbVarNTPCR
ClinVarNTPCR
1000_GenomesNTPCR 
Exome Variant ServerNTPCR
ExAC (Exome Aggregation Consortium)ENSG00000135778
GNOMAD BrowserENSG00000135778
Varsome BrowserNTPCR
Genetic variants : HAPMAP84284
Genomic Variants (DGV)NTPCR [DGVbeta]
DECIPHERNTPCR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNTPCR 
Mutations
ICGC Data PortalNTPCR 
TCGA Data PortalNTPCR 
Broad Tumor PortalNTPCR
OASIS PortalNTPCR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNTPCR  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNTPCR
Mutations and Diseases : HGMDNTPCR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NTPCR
DgiDB (Drug Gene Interaction Database)NTPCR
DoCM (Curated mutations)NTPCR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NTPCR (select a term)
intoGenNTPCR
Cancer3DNTPCR(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETNTPCR
MedgenNTPCR
Genetic Testing Registry NTPCR
NextProtQ9BSD7 [Medical]
TSGene84284
GENETestsNTPCR
Target ValidationNTPCR
Huge Navigator NTPCR [HugePedia]
snp3D : Map Gene to Disease84284
BioCentury BCIQNTPCR
ClinGenNTPCR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84284
Chemical/Pharm GKB GenePA142672508
Clinical trialNTPCR
Miscellaneous
canSAR (ICR)NTPCR (select the gene name)
DataMed IndexNTPCR
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNTPCR
EVEXNTPCR
GoPubMedNTPCR
iHOPNTPCR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 12 15:47:45 CEST 2019
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