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NUB1 (negative regulator of ubiquitin-like proteins 1)

Identity

Alias_symbol (synonym)BS4
NYREN18
NUB1L
Other alias
HGNC (Hugo) NUB1
LocusID (NCBI) 51667
Atlas_Id 43669
Location 7q36.1  [Link to chromosome band 7q36]
Location_base_pair Starts at 151038847 and ends at 151075548 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DTX2 (7q11.23) / NUB1 (7q36.1)NUB1 (7q36.1) / ABCB8 (7q36.1)NUB1 (7q36.1) / NUB1 (7q36.1)
NUB1 (7q36.1) / PPP1R32 (11q12.2)NUB1 (7q36.1) / SPDYA (2p23.2)SPDYA (2p23.2) / NUB1 (7q36.1)
NUB1 7q36.1 / ABCB8 7q36.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NUB1   17623
Cards
Entrez_Gene (NCBI)NUB1  51667  negative regulator of ubiquitin-like proteins 1
AliasesBS4; NUB1L; NYREN18
GeneCards (Weizmann)NUB1
Ensembl hg19 (Hinxton)ENSG00000013374 [Gene_View]  chr7:151038847-151075548 [Contig_View]  NUB1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000013374 [Gene_View]  chr7:151038847-151075548 [Contig_View]  NUB1 [Vega]
ICGC DataPortalENSG00000013374
TCGA cBioPortalNUB1
AceView (NCBI)NUB1
Genatlas (Paris)NUB1
WikiGenes51667
SOURCE (Princeton)NUB1
Genetics Home Reference (NIH)NUB1
Genomic and cartography
GoldenPath hg19 (UCSC)NUB1  -     chr7:151038847-151075548 +  7q36.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NUB1  -     7q36.1   [Description]    (hg38-Dec_2013)
EnsemblNUB1 - 7q36.1 [CytoView hg19]  NUB1 - 7q36.1 [CytoView hg38]
Mapping of homologs : NCBINUB1 [Mapview hg19]  NUB1 [Mapview hg38]
OMIM607981   
Gene and transcription
Genbank (Entrez)AF155099 AF300717 AF459743 AK026433 AK293159
RefSeq transcript (Entrez)NM_001243351 NM_016118
RefSeq genomic (Entrez)NC_000007 NC_018918 NG_029746 NT_007933 NW_004929333
Consensus coding sequences : CCDS (NCBI)NUB1
Cluster EST : UnigeneHs.647082 [ NCBI ]
CGAP (NCI)Hs.647082
Alternative Splicing GalleryENSG00000013374
Gene ExpressionNUB1 [ NCBI-GEO ]   NUB1 [ EBI - ARRAY_EXPRESS ]   NUB1 [ SEEK ]   NUB1 [ MEM ]
Gene Expression Viewer (FireBrowse)NUB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51667
GTEX Portal (Tissue expression)NUB1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5A7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5A7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5A7
Splice isoforms : SwissVarQ9Y5A7
PhosPhoSitePlusQ9Y5A7
Domaine pattern : Prosite (Expaxy)UBA (PS50030)   
Domains : Interpro (EBI)TPR-like_helical_dom    UBA    UBA-like    Ubiquitin-rel_dom   
Domain families : Pfam (Sanger)UBA (PF00627)   
Domain families : Pfam (NCBI)pfam00627   
Domain families : Smart (EMBL)UBA (SM00165)  
Conserved Domain (NCBI)NUB1
DMDM Disease mutations51667
Blocks (Seattle)NUB1
PDB (SRS)1WJU   
PDB (PDBSum)1WJU   
PDB (IMB)1WJU   
PDB (RSDB)1WJU   
Structural Biology KnowledgeBase1WJU   
SCOP (Structural Classification of Proteins)1WJU   
CATH (Classification of proteins structures)1WJU   
SuperfamilyQ9Y5A7
Human Protein AtlasENSG00000013374
Peptide AtlasQ9Y5A7
HPRD07450
IPIIPI00377271   IPI00157365   IPI00981033   IPI00947113   IPI00945879   IPI00945546   IPI00946457   IPI00946056   IPI00946787   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5A7
IntAct (EBI)Q9Y5A7
FunCoupENSG00000013374
BioGRIDNUB1
STRING (EMBL)NUB1
ZODIACNUB1
Ontologies - Pathways
QuickGOQ9Y5A7
Ontology : AmiGOprotein binding  nucleus  ubiquitin-dependent protein catabolic process  protein ubiquitination  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  response to interferon-gamma  response to tumor necrosis factor  
Ontology : EGO-EBIprotein binding  nucleus  ubiquitin-dependent protein catabolic process  protein ubiquitination  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  response to interferon-gamma  response to tumor necrosis factor  
NDEx NetworkNUB1
Atlas of Cancer Signalling NetworkNUB1
Wikipedia pathwaysNUB1
Orthology - Evolution
OrthoDB51667
GeneTree (enSembl)ENSG00000013374
Phylogenetic Trees/Animal Genes : TreeFamNUB1
HOVERGENQ9Y5A7
HOGENOMQ9Y5A7
Homologs : HomoloGeneNUB1
Homology/Alignments : Family Browser (UCSC)NUB1
Gene fusions - Rearrangements
Fusion : MitelmanNUB1/ABCB8 [7q36.1/7q36.1]  
Fusion: TCGANUB1 7q36.1 ABCB8 7q36.1 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUB1
dbVarNUB1
ClinVarNUB1
1000_GenomesNUB1 
Exome Variant ServerNUB1
ExAC (Exome Aggregation Consortium)NUB1 (select the gene name)
Genetic variants : HAPMAP51667
Genomic Variants (DGV)NUB1 [DGVbeta]
DECIPHER (Syndromes)7:151038847-151075548  ENSG00000013374
CONAN: Copy Number AnalysisNUB1 
Mutations
ICGC Data PortalNUB1 
TCGA Data PortalNUB1 
Broad Tumor PortalNUB1
OASIS PortalNUB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUB1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNUB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NUB1
DgiDB (Drug Gene Interaction Database)NUB1
DoCM (Curated mutations)NUB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NUB1 (select a term)
intoGenNUB1
Cancer3DNUB1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607981   
Orphanet
MedgenNUB1
Genetic Testing Registry NUB1
NextProtQ9Y5A7 [Medical]
TSGene51667
GENETestsNUB1
Huge Navigator NUB1 [HugePedia]
snp3D : Map Gene to Disease51667
BioCentury BCIQNUB1
ClinGenNUB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51667
Chemical/Pharm GKB GenePA147357533
Clinical trialNUB1
Miscellaneous
canSAR (ICR)NUB1 (select the gene name)
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNUB1
EVEXNUB1
GoPubMedNUB1
iHOPNUB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:19:32 CET 2017

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