Atlas of Genetics and Cytogenetics in Oncology and Haematology

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NUCB1 (nucleobindin 1)

Identity

Alias (NCBI)CALNUC
NUC
HGNC (Hugo) NUCB1
HGNC Alias symbNUC
Calnuc
LocusID (NCBI) 4924
Atlas_Id 47594
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 48900312 and ends at 48923372 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BAX (19q13.33) / NUCB1 (19q13.33)MYH9 (22q12.3) / NUCB1 (19q13.33)NUCB1 (19q13.33) / FAM83E (19q13.33)
NUCB1 (19q13.33) / IL9R (Xq28)NUCB1 (19q13.33) / NUCB1 (19q13.33)NUCB1 (19q13.33) / SCN8A (12q13.13)
NUCB1 19q13.33 / FAM83E 19q13.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NUCB1   8043
Cards
Entrez_Gene (NCBI)NUCB1    nucleobindin 1
AliasesCALNUC; NUC
GeneCards (Weizmann)NUCB1
Ensembl hg19 (Hinxton)ENSG00000104805 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104805 [Gene_View]  ENSG00000104805 [Sequence]  chr19:48900312-48923372 [Contig_View]  NUCB1 [Vega]
ICGC DataPortalENSG00000104805
TCGA cBioPortalNUCB1
AceView (NCBI)NUCB1
Genatlas (Paris)NUCB1
SOURCE (Princeton)NUCB1
Genetics Home Reference (NIH)NUCB1
Genomic and cartography
GoldenPath hg38 (UCSC)NUCB1  -     chr19:48900312-48923372 +  19q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NUCB1  -     19q13.33   [Description]    (hg19-Feb_2009)
GoldenPathNUCB1 - 19q13.33 [CytoView hg19]  NUCB1 - 19q13.33 [CytoView hg38]
ImmunoBaseENSG00000104805
genome Data Viewer NCBINUCB1 [Mapview hg19]  
OMIM601323   
Gene and transcription
Genbank (Entrez)AI208532 AK025458 AK097790 AK222805 AK292066
RefSeq transcript (Entrez)NM_006184
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NUCB1
Alternative Splicing GalleryENSG00000104805
Gene ExpressionNUCB1 [ NCBI-GEO ]   NUCB1 [ EBI - ARRAY_EXPRESS ]   NUCB1 [ SEEK ]   NUCB1 [ MEM ]
Gene Expression Viewer (FireBrowse)NUCB1 [ Firebrowse - Broad ]
GenevisibleExpression of NUCB1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4924
GTEX Portal (Tissue expression)NUCB1
Human Protein AtlasENSG00000104805-NUCB1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ02818   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ02818  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ02818
Splice isoforms : SwissVarQ02818
PhosPhoSitePlusQ02818
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    NUCB1    Nucleobindin   
Domain families : Pfam (Sanger)EF-hand_7 (PF13499)   
Domain families : Pfam (NCBI)pfam13499   
Conserved Domain (NCBI)NUCB1
Blocks (Seattle)NUCB1
PDB (RSDB)1SNL   
PDB Europe1SNL   
PDB (PDBSum)1SNL   
PDB (IMB)1SNL   
Structural Biology KnowledgeBase1SNL   
SCOP (Structural Classification of Proteins)1SNL   
CATH (Classification of proteins structures)1SNL   
SuperfamilyQ02818
Human Protein Atlas [tissue]ENSG00000104805-NUCB1 [tissue]
Peptide AtlasQ02818
HPRD03205
IPIIPI00295542   IPI00980212   IPI00953072   IPI00893068   IPI00892947   IPI00892782   IPI00892657   
Protein Interaction databases
DIP (DOE-UCLA)Q02818
IntAct (EBI)Q02818
BioGRIDNUCB1
STRING (EMBL)NUCB1
ZODIACNUCB1
Ontologies - Pathways
QuickGOQ02818
Ontology : AmiGOG-protein alpha-subunit binding  DNA binding  guanyl-nucleotide exchange factor activity  calcium ion binding  protein binding  extracellular space  nucleus  early endosome  endoplasmic reticulum lumen  rough endoplasmic reticulum  endoplasmic reticulum-Golgi intermediate compartment  endoplasmic reticulum-Golgi intermediate compartment  Golgi-associated vesicle  cis-Golgi network  trans-Golgi network  small GTPase mediated signal transduction  membrane  Golgi cisterna membrane  post-translational protein modification  cellular protein metabolic process  regulation of catalytic activity  extracellular exosome  response to cisplatin  extrinsic component of Golgi membrane  lumenal side of Golgi membrane  regulation of protein targeting  
Ontology : EGO-EBIG-protein alpha-subunit binding  DNA binding  guanyl-nucleotide exchange factor activity  calcium ion binding  protein binding  extracellular space  nucleus  early endosome  endoplasmic reticulum lumen  rough endoplasmic reticulum  endoplasmic reticulum-Golgi intermediate compartment  endoplasmic reticulum-Golgi intermediate compartment  Golgi-associated vesicle  cis-Golgi network  trans-Golgi network  small GTPase mediated signal transduction  membrane  Golgi cisterna membrane  post-translational protein modification  cellular protein metabolic process  regulation of catalytic activity  extracellular exosome  response to cisplatin  extrinsic component of Golgi membrane  lumenal side of Golgi membrane  regulation of protein targeting  
NDEx NetworkNUCB1
Atlas of Cancer Signalling NetworkNUCB1
Wikipedia pathwaysNUCB1
Orthology - Evolution
OrthoDB4924
GeneTree (enSembl)ENSG00000104805
Phylogenetic Trees/Animal Genes : TreeFamNUCB1
HOGENOMQ02818
Homologs : HomoloGeneNUCB1
Homology/Alignments : Family Browser (UCSC)NUCB1
Gene fusions - Rearrangements
Fusion : MitelmanNUCB1/FAM83E [19q13.33/19q13.33]  
Fusion PortalNUCB1 19q13.33 FAM83E 19q13.33 OV
Fusion : QuiverNUCB1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUCB1 [hg38]
dbVarNUCB1
ClinVarNUCB1
MonarchNUCB1
1000_GenomesNUCB1 
Exome Variant ServerNUCB1
GNOMAD BrowserENSG00000104805
Varsome BrowserNUCB1
Genomic Variants (DGV)NUCB1 [DGVbeta]
DECIPHERNUCB1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNUCB1 
Mutations
ICGC Data PortalNUCB1 
TCGA Data PortalNUCB1 
Broad Tumor PortalNUCB1
OASIS PortalNUCB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUCB1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNUCB1
Mutations and Diseases : HGMDNUCB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NUCB1
DgiDB (Drug Gene Interaction Database)NUCB1
DoCM (Curated mutations)NUCB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NUCB1 (select a term)
intoGenNUCB1
Cancer3DNUCB1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601323   
Orphanet
DisGeNETNUCB1
MedgenNUCB1
Genetic Testing Registry NUCB1
NextProtQ02818 [Medical]
GENETestsNUCB1
Target ValidationNUCB1
Huge Navigator NUCB1 [HugePedia]
ClinGenNUCB1
Clinical trials, drugs, therapy
MyCancerGenomeNUCB1
Protein Interactions : CTD
Pharm GKB GenePA31825
PharosQ02818
Clinical trialNUCB1
Miscellaneous
canSAR (ICR)NUCB1 (select the gene name)
HarmonizomeNUCB1
DataMed IndexNUCB1
Probes
Litterature
PubMed54 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNUCB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:37:20 CET 2021
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