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NUDT15 (nudix hydrolase 15)

Identity

Alias_namesnudix (nucleoside diphosphate linked moiety X)-type motif 15
Alias_symbol (synonym)MTH2
FLJ10956
Other aliasNUDT15D
HGNC (Hugo) NUDT15
LocusID (NCBI) 55270
Atlas_Id 55280
Location 13q14.2  [Link to chromosome band 13q14]
Location_base_pair Starts at 48037567 and ends at 48041502 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NUDT15   23063
Cards
Entrez_Gene (NCBI)NUDT15  55270  nudix hydrolase 15
AliasesMTH2; NUDT15D
GeneCards (Weizmann)NUDT15
Ensembl hg19 (Hinxton)ENSG00000136159 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136159 [Gene_View]  chr13:48037567-48041502 [Contig_View]  NUDT15 [Vega]
ICGC DataPortalENSG00000136159
TCGA cBioPortalNUDT15
AceView (NCBI)NUDT15
Genatlas (Paris)NUDT15
WikiGenes55270
SOURCE (Princeton)NUDT15
Genetics Home Reference (NIH)NUDT15
Genomic and cartography
GoldenPath hg38 (UCSC)NUDT15  -     chr13:48037567-48041502 +  13q14.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NUDT15  -     13q14.2   [Description]    (hg19-Feb_2009)
EnsemblNUDT15 - 13q14.2 [CytoView hg19]  NUDT15 - 13q14.2 [CytoView hg38]
Mapping of homologs : NCBINUDT15 [Mapview hg19]  NUDT15 [Mapview hg38]
OMIM615792   616903   
Gene and transcription
Genbank (Entrez)AK001818 BC050698 BC064607 BC107875 BC133015
RefSeq transcript (Entrez)NM_001304745 NM_018283
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NUDT15
Cluster EST : UnigeneHs.144407 [ NCBI ]
CGAP (NCI)Hs.144407
Alternative Splicing GalleryENSG00000136159
Gene ExpressionNUDT15 [ NCBI-GEO ]   NUDT15 [ EBI - ARRAY_EXPRESS ]   NUDT15 [ SEEK ]   NUDT15 [ MEM ]
Gene Expression Viewer (FireBrowse)NUDT15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55270
GTEX Portal (Tissue expression)NUDT15
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NV35   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NV35  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NV35
Splice isoforms : SwissVarQ9NV35
PhosPhoSitePlusQ9NV35
Domaine pattern : Prosite (Expaxy)NUDIX (PS51462)   
Domains : Interpro (EBI)NUDIX_hydrolase_dom    NUDIX_hydrolase_dom-like   
Domain families : Pfam (Sanger)NUDIX (PF00293)   
Domain families : Pfam (NCBI)pfam00293   
Conserved Domain (NCBI)NUDT15
DMDM Disease mutations55270
Blocks (Seattle)NUDT15
PDB (SRS)5BON    5LPG   
PDB (PDBSum)5BON    5LPG   
PDB (IMB)5BON    5LPG   
PDB (RSDB)5BON    5LPG   
Structural Biology KnowledgeBase5BON    5LPG   
SCOP (Structural Classification of Proteins)5BON    5LPG   
CATH (Classification of proteins structures)5BON    5LPG   
SuperfamilyQ9NV35
Human Protein AtlasENSG00000136159
Peptide AtlasQ9NV35
HPRD14848
IPIIPI00019487   
Protein Interaction databases
DIP (DOE-UCLA)Q9NV35
IntAct (EBI)Q9NV35
FunCoupENSG00000136159
BioGRIDNUDT15
STRING (EMBL)NUDT15
ZODIACNUDT15
Ontologies - Pathways
QuickGOQ9NV35
Ontology : AmiGOmitotic cell cycle  protein binding  cytosol  cytosol  purine nucleotide catabolic process  dGTP catabolic process  8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity  nucleoside-diphosphatase activity  nucleobase-containing small molecule catabolic process  NADH pyrophosphatase activity  8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity  8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity  DNA protection  DNA protection  exogenous drug catabolic process  metal ion binding  nucleoside-triphosphate diphosphatase activity  regulation of proteasomal protein catabolic process  nucleoside phosphate catabolic process  nucleoside phosphate catabolic process  
Ontology : EGO-EBImitotic cell cycle  protein binding  cytosol  cytosol  purine nucleotide catabolic process  dGTP catabolic process  8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity  nucleoside-diphosphatase activity  nucleobase-containing small molecule catabolic process  NADH pyrophosphatase activity  8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity  8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity  DNA protection  DNA protection  exogenous drug catabolic process  metal ion binding  nucleoside-triphosphate diphosphatase activity  regulation of proteasomal protein catabolic process  nucleoside phosphate catabolic process  nucleoside phosphate catabolic process  
NDEx NetworkNUDT15
Atlas of Cancer Signalling NetworkNUDT15
Wikipedia pathwaysNUDT15
Orthology - Evolution
OrthoDB55270
GeneTree (enSembl)ENSG00000136159
Phylogenetic Trees/Animal Genes : TreeFamNUDT15
HOVERGENQ9NV35
HOGENOMQ9NV35
Homologs : HomoloGeneNUDT15
Homology/Alignments : Family Browser (UCSC)NUDT15
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUDT15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUDT15
dbVarNUDT15
ClinVarNUDT15
1000_GenomesNUDT15 
Exome Variant ServerNUDT15
ExAC (Exome Aggregation Consortium)NUDT15 (select the gene name)
Genetic variants : HAPMAP55270
Genomic Variants (DGV)NUDT15 [DGVbeta]
DECIPHERNUDT15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNUDT15 
Mutations
ICGC Data PortalNUDT15 
TCGA Data PortalNUDT15 
Broad Tumor PortalNUDT15
OASIS PortalNUDT15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUDT15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNUDT15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NUDT15
DgiDB (Drug Gene Interaction Database)NUDT15
DoCM (Curated mutations)NUDT15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NUDT15 (select a term)
intoGenNUDT15
Cancer3DNUDT15(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615792    616903   
Orphanet23063   
MedgenNUDT15
Genetic Testing Registry NUDT15
NextProtQ9NV35 [Medical]
TSGene55270
GENETestsNUDT15
Target ValidationNUDT15
Huge Navigator NUDT15 [HugePedia]
snp3D : Map Gene to Disease55270
BioCentury BCIQNUDT15
ClinGenNUDT15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55270
Chemical/Pharm GKB GenePA134963132
Clinical trialNUDT15
Miscellaneous
canSAR (ICR)NUDT15 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNUDT15
EVEXNUDT15
GoPubMedNUDT15
iHOPNUDT15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 17:09:33 CEST 2017

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