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NUDT2 (nudix hydrolase 2)

Identity

Alias_namesAPAH1
nudix (nucleoside diphosphate linked moiety X)-type motif 2
Other alias
HGNC (Hugo) NUDT2
LocusID (NCBI) 318
Atlas_Id 41592
Location 9p13.3  [Link to chromosome band 9p13]
Location_base_pair Starts at 34329506 and ends at 34343713 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NUDT2 (9p13.3) / GLIPR2 (9p13.3)NUDT2 (9p13.3) / NUDT2 (9p13.3)NUDT2 9p13.3 / GLIPR2 9p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NUDT2   8049
Cards
Entrez_Gene (NCBI)NUDT2  318  nudix hydrolase 2
AliasesAPAH1
GeneCards (Weizmann)NUDT2
Ensembl hg19 (Hinxton)ENSG00000164978 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164978 [Gene_View]  chr9:34329506-34343713 [Contig_View]  NUDT2 [Vega]
ICGC DataPortalENSG00000164978
TCGA cBioPortalNUDT2
AceView (NCBI)NUDT2
Genatlas (Paris)NUDT2
WikiGenes318
SOURCE (Princeton)NUDT2
Genetics Home Reference (NIH)NUDT2
Genomic and cartography
GoldenPath hg38 (UCSC)NUDT2  -     chr9:34329506-34343713 +  9p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NUDT2  -     9p13.3   [Description]    (hg19-Feb_2009)
EnsemblNUDT2 - 9p13.3 [CytoView hg19]  NUDT2 - 9p13.3 [CytoView hg38]
Mapping of homologs : NCBINUDT2 [Mapview hg19]  NUDT2 [Mapview hg38]
OMIM602852   
Gene and transcription
Genbank (Entrez)AA310093 AA398857 AK310574 BC004926 BG622439
RefSeq transcript (Entrez)NM_001161 NM_001244390 NM_147172 NM_147173
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NUDT2
Cluster EST : UnigeneHs.731743 [ NCBI ]
CGAP (NCI)Hs.731743
Alternative Splicing GalleryENSG00000164978
Gene ExpressionNUDT2 [ NCBI-GEO ]   NUDT2 [ EBI - ARRAY_EXPRESS ]   NUDT2 [ SEEK ]   NUDT2 [ MEM ]
Gene Expression Viewer (FireBrowse)NUDT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)318
GTEX Portal (Tissue expression)NUDT2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP50583   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP50583  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP50583
Splice isoforms : SwissVarP50583
Catalytic activity : Enzyme3.6.1.17 [ Enzyme-Expasy ]   3.6.1.173.6.1.17 [ IntEnz-EBI ]   3.6.1.17 [ BRENDA ]   3.6.1.17 [ KEGG ]   
PhosPhoSitePlusP50583
Domaine pattern : Prosite (Expaxy)NUDIX (PS51462)    NUDIX_BOX (PS00893)   
Domains : Interpro (EBI)NUDIX_hydrolase_CS    NUDIX_hydrolase_dom    NUDIX_hydrolase_dom-like    Tetra_PHTase   
Domain families : Pfam (Sanger)NUDIX (PF00293)   
Domain families : Pfam (NCBI)pfam00293   
Conserved Domain (NCBI)NUDT2
DMDM Disease mutations318
Blocks (Seattle)NUDT2
PDB (SRS)1XSA    1XSB    1XSC    3U53    4ICK    4IJX   
PDB (PDBSum)1XSA    1XSB    1XSC    3U53    4ICK    4IJX   
PDB (IMB)1XSA    1XSB    1XSC    3U53    4ICK    4IJX   
PDB (RSDB)1XSA    1XSB    1XSC    3U53    4ICK    4IJX   
Structural Biology KnowledgeBase1XSA    1XSB    1XSC    3U53    4ICK    4IJX   
SCOP (Structural Classification of Proteins)1XSA    1XSB    1XSC    3U53    4ICK    4IJX   
CATH (Classification of proteins structures)1XSA    1XSB    1XSC    3U53    4ICK    4IJX   
SuperfamilyP50583
Human Protein AtlasENSG00000164978
Peptide AtlasP50583
HPRD04168
IPIIPI00221231   
Protein Interaction databases
DIP (DOE-UCLA)P50583
IntAct (EBI)P50583
FunCoupENSG00000164978
BioGRIDNUDT2
STRING (EMBL)NUDT2
ZODIACNUDT2
Ontologies - Pathways
QuickGOP50583
Ontology : AmiGOresponse to reactive oxygen species  bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity  bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity  protein binding  GTP binding  mitochondrial matrix  nucleobase-containing compound metabolic process  apoptotic process  bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity  
Ontology : EGO-EBIresponse to reactive oxygen species  bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity  bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity  protein binding  GTP binding  mitochondrial matrix  nucleobase-containing compound metabolic process  apoptotic process  bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity  
Pathways : KEGGPurine metabolism    Pyrimidine metabolism   
NDEx NetworkNUDT2
Atlas of Cancer Signalling NetworkNUDT2
Wikipedia pathwaysNUDT2
Orthology - Evolution
OrthoDB318
GeneTree (enSembl)ENSG00000164978
Phylogenetic Trees/Animal Genes : TreeFamNUDT2
HOVERGENP50583
HOGENOMP50583
Homologs : HomoloGeneNUDT2
Homology/Alignments : Family Browser (UCSC)NUDT2
Gene fusions - Rearrangements
Fusion : MitelmanNUDT2/GLIPR2 [9p13.3/9p13.3]  
Fusion: TCGANUDT2 9p13.3 GLIPR2 9p13.3 GBM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUDT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUDT2
dbVarNUDT2
ClinVarNUDT2
1000_GenomesNUDT2 
Exome Variant ServerNUDT2
ExAC (Exome Aggregation Consortium)NUDT2 (select the gene name)
Genetic variants : HAPMAP318
Genomic Variants (DGV)NUDT2 [DGVbeta]
DECIPHERNUDT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNUDT2 
Mutations
ICGC Data PortalNUDT2 
TCGA Data PortalNUDT2 
Broad Tumor PortalNUDT2
OASIS PortalNUDT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUDT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNUDT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NUDT2
DgiDB (Drug Gene Interaction Database)NUDT2
DoCM (Curated mutations)NUDT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NUDT2 (select a term)
intoGenNUDT2
Cancer3DNUDT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602852   
Orphanet
MedgenNUDT2
Genetic Testing Registry NUDT2
NextProtP50583 [Medical]
TSGene318
GENETestsNUDT2
Huge Navigator NUDT2 [HugePedia]
snp3D : Map Gene to Disease318
BioCentury BCIQNUDT2
ClinGenNUDT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD318
Chemical/Pharm GKB GenePA31833
Clinical trialNUDT2
Miscellaneous
canSAR (ICR)NUDT2 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNUDT2
EVEXNUDT2
GoPubMedNUDT2
iHOPNUDT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:29:24 CEST 2017

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