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NUDT3 (nudix hydrolase 3)

Identity

Alias_namesnudix (nucleoside diphosphate linked moiety X)-type motif 3
Alias_symbol (synonym)DIPP
Other aliasDIPP-1
DIPP1
HGNC (Hugo) NUDT3
LocusID (NCBI) 11165
Atlas_Id 71027
Location 6p21.31  [Link to chromosome band 6p21]
Location_base_pair Starts at 34287196 and ends at 34392680 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NUDT3 (6p21.31) / ARL8B (3p26.1)NUDT3 (6p21.31) / CDH12 (5p14.3)NUDT3 (6p21.31) / CHD3 (17p13.1)
NUDT3 (6p21.31) / NUDT3 (6p21.31)NUDT3 (6p21.31) / SERINC5 (5q14.1)NUDT3 (6p21.31) / SORBS2 (4q35.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NUDT3   8050
Cards
Entrez_Gene (NCBI)NUDT3  11165  nudix hydrolase 3
AliasesDIPP; DIPP-1; DIPP1
GeneCards (Weizmann)NUDT3
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr6:34287196-34392680 [Contig_View]  NUDT3 [Vega]
TCGA cBioPortalNUDT3
AceView (NCBI)NUDT3
Genatlas (Paris)NUDT3
WikiGenes11165
SOURCE (Princeton)NUDT3
Genetics Home Reference (NIH)NUDT3
Genomic and cartography
GoldenPath hg38 (UCSC)NUDT3  -     chr6:34287196-34392680 -  6p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NUDT3  -     6p21.31   [Description]    (hg19-Feb_2009)
EnsemblNUDT3 - 6p21.31 [CytoView hg19]  NUDT3 - 6p21.31 [CytoView hg38]
Mapping of homologs : NCBINUDT3 [Mapview hg19]  NUDT3 [Mapview hg38]
OMIM609228   
Gene and transcription
Genbank (Entrez)AF062529 AF062530 AK313440 BC007727 BC024593
RefSeq transcript (Entrez)NM_006703
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NUDT3
Cluster EST : UnigeneHs.188882 [ NCBI ]
CGAP (NCI)Hs.188882
Gene ExpressionNUDT3 [ NCBI-GEO ]   NUDT3 [ EBI - ARRAY_EXPRESS ]   NUDT3 [ SEEK ]   NUDT3 [ MEM ]
Gene Expression Viewer (FireBrowse)NUDT3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11165
GTEX Portal (Tissue expression)NUDT3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95989   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95989  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95989
Splice isoforms : SwissVarO95989
Catalytic activity : Enzyme3.6.1.52 [ Enzyme-Expasy ]   3.6.1.523.6.1.52 [ IntEnz-EBI ]   3.6.1.52 [ BRENDA ]   3.6.1.52 [ KEGG ]   
PhosPhoSitePlusO95989
Domaine pattern : Prosite (Expaxy)NUDIX (PS51462)    NUDIX_BOX (PS00893)   
Domains : Interpro (EBI)NUDIX_hydrolase_CS    NUDIX_hydrolase_dom    NUDIX_hydrolase_dom-like   
Domain families : Pfam (Sanger)NUDIX (PF00293)   
Domain families : Pfam (NCBI)pfam00293   
Conserved Domain (NCBI)NUDT3
DMDM Disease mutations11165
Blocks (Seattle)NUDT3
PDB (SRS)2FVV    2Q9P   
PDB (PDBSum)2FVV    2Q9P   
PDB (IMB)2FVV    2Q9P   
PDB (RSDB)2FVV    2Q9P   
Structural Biology KnowledgeBase2FVV    2Q9P   
SCOP (Structural Classification of Proteins)2FVV    2Q9P   
CATH (Classification of proteins structures)2FVV    2Q9P   
SuperfamilyO95989
Peptide AtlasO95989
HPRD14849
IPIIPI00009148   
Protein Interaction databases
DIP (DOE-UCLA)O95989
IntAct (EBI)O95989
BioGRIDNUDT3
STRING (EMBL)NUDT3
ZODIACNUDT3
Ontologies - Pathways
QuickGOO95989
Ontology : AmiGOmagnesium ion binding  endopolyphosphatase activity  nucleus  cytoplasm  cytosol  cytosol  cell-cell signaling  diphosphoinositol-polyphosphate diphosphatase activity  diadenosine polyphosphate catabolic process  bis(5'-adenosyl)-hexaphosphatase activity  bis(5'-adenosyl)-pentaphosphatase activity  inositol phosphate metabolic process  m7G(5')pppN diphosphatase activity  inositol diphosphate tetrakisphosphate diphosphatase activity  inositol bisdiphosphate tetrakisphosphate diphosphatase activity  inositol diphosphate pentakisphosphate diphosphatase activity  inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity  inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity  inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity  inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity  inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity  inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity  extracellular exosome  diphosphoinositol polyphosphate catabolic process  diadenosine pentaphosphate catabolic process  diadenosine hexaphosphate catabolic process  adenosine 5'-(hexahydrogen pentaphosphate) catabolic process  
Ontology : EGO-EBImagnesium ion binding  endopolyphosphatase activity  nucleus  cytoplasm  cytosol  cytosol  cell-cell signaling  diphosphoinositol-polyphosphate diphosphatase activity  diadenosine polyphosphate catabolic process  bis(5'-adenosyl)-hexaphosphatase activity  bis(5'-adenosyl)-pentaphosphatase activity  inositol phosphate metabolic process  m7G(5')pppN diphosphatase activity  inositol diphosphate tetrakisphosphate diphosphatase activity  inositol bisdiphosphate tetrakisphosphate diphosphatase activity  inositol diphosphate pentakisphosphate diphosphatase activity  inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity  inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity  inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity  inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity  inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity  inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity  extracellular exosome  diphosphoinositol polyphosphate catabolic process  diadenosine pentaphosphate catabolic process  diadenosine hexaphosphate catabolic process  adenosine 5'-(hexahydrogen pentaphosphate) catabolic process  
NDEx NetworkNUDT3
Atlas of Cancer Signalling NetworkNUDT3
Wikipedia pathwaysNUDT3
Orthology - Evolution
OrthoDB11165
Phylogenetic Trees/Animal Genes : TreeFamNUDT3
HOVERGENO95989
HOGENOMO95989
Homologs : HomoloGeneNUDT3
Homology/Alignments : Family Browser (UCSC)NUDT3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUDT3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUDT3
dbVarNUDT3
ClinVarNUDT3
1000_GenomesNUDT3 
Exome Variant ServerNUDT3
ExAC (Exome Aggregation Consortium)NUDT3 (select the gene name)
Genetic variants : HAPMAP11165
Genomic Variants (DGV)NUDT3 [DGVbeta]
DECIPHERNUDT3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNUDT3 
Mutations
ICGC Data PortalNUDT3 
TCGA Data PortalNUDT3 
Broad Tumor PortalNUDT3
OASIS PortalNUDT3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUDT3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNUDT3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NUDT3
DgiDB (Drug Gene Interaction Database)NUDT3
DoCM (Curated mutations)NUDT3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NUDT3 (select a term)
intoGenNUDT3
Cancer3DNUDT3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609228   
Orphanet
MedgenNUDT3
Genetic Testing Registry NUDT3
NextProtO95989 [Medical]
TSGene11165
GENETestsNUDT3
Target ValidationNUDT3
Huge Navigator NUDT3 [HugePedia]
snp3D : Map Gene to Disease11165
BioCentury BCIQNUDT3
ClinGenNUDT3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11165
Chemical/Pharm GKB GenePA31834
Clinical trialNUDT3
Miscellaneous
canSAR (ICR)NUDT3 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNUDT3
EVEXNUDT3
GoPubMedNUDT3
iHOPNUDT3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:32:26 CEST 2017

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