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NUDT3 (nudix hydrolase 3)

Identity

Alias (NCBI)DIPP
DIPP-1
DIPP1
HGNC (Hugo) NUDT3
HGNC Alias symbDIPP
HGNC Previous namenudix (nucleoside diphosphate linked moiety X)-type motif 3
LocusID (NCBI) 11165
Atlas_Id 71027
Location 6p21.31  [Link to chromosome band 6p21]
Location_base_pair Starts at 34279679 and ends at 34392669 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NUDT3 (6p21.31)::ARL8B (3p26.1)NUDT3 (6p21.31)::CDH12 (5p14.3)NUDT3 (6p21.31)::CHD3 (17p13.1)
NUDT3 (6p21.31)::NUDT3 (6p21.31)NUDT3 (6p21.31)::SERINC5 (5q14.1)NUDT3 (6p21.31)::SORBS2 (4q35.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)NUDT3   8050
Cards
Entrez_Gene (NCBI)NUDT3    nudix hydrolase 3
AliasesDIPP; DIPP-1; DIPP1
GeneCards (Weizmann)NUDT3
Ensembl hg19 (Hinxton)ENSG00000272325 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000272325 [Gene_View]  ENSG00000272325 [Sequence]  chr6:34279679-34392669 [Contig_View]  NUDT3 [Vega]
ICGC DataPortalENSG00000272325
TCGA cBioPortalNUDT3
AceView (NCBI)NUDT3
Genatlas (Paris)NUDT3
SOURCE (Princeton)NUDT3
Genetics Home Reference (NIH)NUDT3
Genomic and cartography
GoldenPath hg38 (UCSC)NUDT3  -     chr6:34279679-34392669 -  6p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NUDT3  -     6p21.31   [Description]    (hg19-Feb_2009)
GoldenPathNUDT3 - 6p21.31 [CytoView hg19]  NUDT3 - 6p21.31 [CytoView hg38]
ImmunoBaseENSG00000272325
Genome Data Viewer NCBINUDT3 [Mapview hg19]  
OMIM609228   
Gene and transcription
Genbank (Entrez)AF062529 AF062530 AK313440 BC007727 BC024593
RefSeq transcript (Entrez)NM_006703
Consensus coding sequences : CCDS (NCBI)NUDT3
Gene ExpressionNUDT3 [ NCBI-GEO ]   NUDT3 [ EBI - ARRAY_EXPRESS ]   NUDT3 [ SEEK ]   NUDT3 [ MEM ]
Gene Expression Viewer (FireBrowse)NUDT3 [ Firebrowse - Broad ]
GenevisibleExpression of NUDT3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11165
GTEX Portal (Tissue expression)NUDT3
Human Protein AtlasENSG00000272325-NUDT3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95989   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95989  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95989
Catalytic activity : Enzyme3.6.1.- [ Enzyme-Expasy ]   3.6.1.-3.6.1.- [ IntEnz-EBI ]   3.6.1.- [ BRENDA ]   3.6.1.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusO95989
Domaine pattern : Prosite (Expaxy)NUDIX (PS51462)    NUDIX_BOX (PS00893)   
Domains : Interpro (EBI)NUDIX_hydrolase-like_dom_sf    NUDIX_hydrolase_CS    NUDIX_hydrolase_dom   
Domain families : Pfam (Sanger)NUDIX (PF00293)   
Domain families : Pfam (NCBI)pfam00293   
Conserved Domain (NCBI)NUDT3
PDB (RSDB)2FVV    2Q9P    6PCK    6PCL   
PDB Europe2FVV    2Q9P    6PCK    6PCL   
PDB (PDBSum)2FVV    2Q9P    6PCK    6PCL   
PDB (IMB)2FVV    2Q9P    6PCK    6PCL   
Structural Biology KnowledgeBase2FVV    2Q9P    6PCK    6PCL   
SCOP (Structural Classification of Proteins)2FVV    2Q9P    6PCK    6PCL   
CATH (Classification of proteins structures)2FVV    2Q9P    6PCK    6PCL   
SuperfamilyO95989
AlphaFold pdb e-kbO95989   
Human Protein Atlas [tissue]ENSG00000272325-NUDT3 [tissue]
HPRD14849
Protein Interaction databases
DIP (DOE-UCLA)O95989
IntAct (EBI)O95989
BioGRIDNUDT3
STRING (EMBL)NUDT3
ZODIACNUDT3
Ontologies - Pathways
QuickGOO95989
Ontology : AmiGOmagnesium ion binding  endopolyphosphatase activity  protein binding  nucleus  cytoplasm  cytosol  cytosol  cell-cell signaling  diphosphoinositol-polyphosphate diphosphatase activity  diphosphoinositol-polyphosphate diphosphatase activity  diadenosine polyphosphate catabolic process  bis(5'-adenosyl)-hexaphosphatase activity  bis(5'-adenosyl)-pentaphosphatase activity  inositol phosphate metabolic process  m7G(5')pppN diphosphatase activity  inositol diphosphate tetrakisphosphate diphosphatase activity  inositol diphosphate pentakisphosphate diphosphatase activity  diphosphoinositol polyphosphate metabolic process  diphosphoinositol polyphosphate catabolic process  diadenosine pentaphosphate catabolic process  diadenosine hexaphosphate catabolic process  adenosine 5'-(hexahydrogen pentaphosphate) catabolic process  
Ontology : EGO-EBImagnesium ion binding  endopolyphosphatase activity  protein binding  nucleus  cytoplasm  cytosol  cytosol  cell-cell signaling  diphosphoinositol-polyphosphate diphosphatase activity  diphosphoinositol-polyphosphate diphosphatase activity  diadenosine polyphosphate catabolic process  bis(5'-adenosyl)-hexaphosphatase activity  bis(5'-adenosyl)-pentaphosphatase activity  inositol phosphate metabolic process  m7G(5')pppN diphosphatase activity  inositol diphosphate tetrakisphosphate diphosphatase activity  inositol diphosphate pentakisphosphate diphosphatase activity  diphosphoinositol polyphosphate metabolic process  diphosphoinositol polyphosphate catabolic process  diadenosine pentaphosphate catabolic process  diadenosine hexaphosphate catabolic process  adenosine 5'-(hexahydrogen pentaphosphate) catabolic process  
NDEx NetworkNUDT3
Atlas of Cancer Signalling NetworkNUDT3
Wikipedia pathwaysNUDT3
Orthology - Evolution
OrthoDB11165
GeneTree (enSembl)ENSG00000272325
Phylogenetic Trees/Animal Genes : TreeFamNUDT3
Homologs : HomoloGeneNUDT3
Homology/Alignments : Family Browser (UCSC)NUDT3
Gene fusions - Rearrangements
Fusion : QuiverNUDT3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUDT3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUDT3
dbVarNUDT3
ClinVarNUDT3
MonarchNUDT3
1000_GenomesNUDT3 
Exome Variant ServerNUDT3
GNOMAD BrowserENSG00000272325
Varsome BrowserNUDT3
ACMGNUDT3 variants
VarityO95989
Genomic Variants (DGV)NUDT3 [DGVbeta]
DECIPHERNUDT3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNUDT3 
Mutations
ICGC Data PortalNUDT3 
TCGA Data PortalNUDT3 
Broad Tumor PortalNUDT3
OASIS PortalNUDT3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUDT3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNUDT3
Mutations and Diseases : HGMDNUDT3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNUDT3
DgiDB (Drug Gene Interaction Database)NUDT3
DoCM (Curated mutations)NUDT3
CIViC (Clinical Interpretations of Variants in Cancer)NUDT3
Cancer3DNUDT3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609228   
Orphanet
DisGeNETNUDT3
MedgenNUDT3
Genetic Testing Registry NUDT3
NextProtO95989 [Medical]
GENETestsNUDT3
Target ValidationNUDT3
Huge Navigator NUDT3 [HugePedia]
ClinGenNUDT3
Clinical trials, drugs, therapy
MyCancerGenomeNUDT3
Protein Interactions : CTDNUDT3
Pharm GKB GenePA31834
PharosO95989
Clinical trialNUDT3
Miscellaneous
canSAR (ICR)NUDT3
HarmonizomeNUDT3
ARCHS4NUDT3
DataMed IndexNUDT3
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNUDT3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun Jan 16 19:16:45 CET 2022

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