Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NUDT4 (nudix hydrolase 4)

Identity

Alias_namesnudix (nucleoside diphosphate linked moiety X)-type motif 4
Alias_symbol (synonym)DIPP2
HDCMB47P
KIAA0487
DIPP2alpha
DIPP2beta
Other alias
HGNC (Hugo) NUDT4
LocusID (NCBI) 11163
Atlas_Id 71028
Location 12q22  [Link to chromosome band 12q22]
Location_base_pair Starts at 93378550 and ends at 93403248 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NUDT4 (12q22) / ADD1 (4p16.3)NUDT4 (12q22) / LRRC57 (15q15.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(4;12)(p16;q22) NUDT4/ADD1


External links

Nomenclature
HGNC (Hugo)NUDT4   8051
Cards
Entrez_Gene (NCBI)NUDT4  11163  nudix hydrolase 4
AliasesDIPP2; DIPP2alpha; DIPP2beta; HDCMB47P
GeneCards (Weizmann)NUDT4
Ensembl hg19 (Hinxton)ENSG00000173598 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173598 [Gene_View]  ENSG00000173598 [Sequence]  chr12:93378550-93403248 [Contig_View]  NUDT4 [Vega]
ICGC DataPortalENSG00000173598
TCGA cBioPortalNUDT4
AceView (NCBI)NUDT4
Genatlas (Paris)NUDT4
WikiGenes11163
SOURCE (Princeton)NUDT4
Genetics Home Reference (NIH)NUDT4
Genomic and cartography
GoldenPath hg38 (UCSC)NUDT4  -     chr12:93378550-93403248 +  12q22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NUDT4  -     12q22   [Description]    (hg19-Feb_2009)
EnsemblNUDT4 - 12q22 [CytoView hg19]  NUDT4 - 12q22 [CytoView hg38]
Mapping of homologs : NCBINUDT4 [Mapview hg19]  NUDT4 [Mapview hg38]
OMIM609229   
Gene and transcription
Genbank (Entrez)AB007956 AF067803 AF191649 AF191650 AF191651
RefSeq transcript (Entrez)NM_001301022 NM_001301023 NM_001301024 NM_019094 NM_199040
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NUDT4
Cluster EST : UnigeneHs.506325 [ NCBI ]
CGAP (NCI)Hs.506325
Alternative Splicing GalleryENSG00000173598
Gene ExpressionNUDT4 [ NCBI-GEO ]   NUDT4 [ EBI - ARRAY_EXPRESS ]   NUDT4 [ SEEK ]   NUDT4 [ MEM ]
Gene Expression Viewer (FireBrowse)NUDT4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11163
GTEX Portal (Tissue expression)NUDT4
Human Protein AtlasENSG00000173598-NUDT4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZJ9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZJ9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZJ9
Splice isoforms : SwissVarQ9NZJ9
Catalytic activity : Enzyme3.6.1.52 [ Enzyme-Expasy ]   3.6.1.523.6.1.52 [ IntEnz-EBI ]   3.6.1.52 [ BRENDA ]   3.6.1.52 [ KEGG ]   
PhosPhoSitePlusQ9NZJ9
Domaine pattern : Prosite (Expaxy)NUDIX (PS51462)    NUDIX_BOX (PS00893)   
Domains : Interpro (EBI)NUDIX_hydrolase_CS    NUDIX_hydrolase_dom    NUDIX_hydrolase_dom-like   
Domain families : Pfam (Sanger)NUDIX (PF00293)   
Domain families : Pfam (NCBI)pfam00293   
Conserved Domain (NCBI)NUDT4
DMDM Disease mutations11163
Blocks (Seattle)NUDT4
SuperfamilyQ9NZJ9
Human Protein Atlas [tissue]ENSG00000173598-NUDT4 [tissue]
Peptide AtlasQ9NZJ9
HPRD14850
IPIIPI00607685   IPI00396090   IPI01021057   IPI01021194   IPI01021035   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZJ9
IntAct (EBI)Q9NZJ9
FunCoupENSG00000173598
BioGRIDNUDT4
STRING (EMBL)NUDT4
ZODIACNUDT4
Ontologies - Pathways
QuickGOQ9NZJ9
Ontology : AmiGO###############################################################################################################################################################################################################################################################  
Ontology : EGO-EBI###############################################################################################################################################################################################################################################################  
NDEx NetworkNUDT4
Atlas of Cancer Signalling NetworkNUDT4
Wikipedia pathwaysNUDT4
Orthology - Evolution
OrthoDB11163
GeneTree (enSembl)ENSG00000173598
Phylogenetic Trees/Animal Genes : TreeFamNUDT4
HOVERGENQ9NZJ9
HOGENOMQ9NZJ9
Homologs : HomoloGeneNUDT4
Homology/Alignments : Family Browser (UCSC)NUDT4
Gene fusions - Rearrangements
Fusion : QuiverNUDT4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUDT4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUDT4
dbVarNUDT4
ClinVarNUDT4
1000_GenomesNUDT4 
Exome Variant ServerNUDT4
ExAC (Exome Aggregation Consortium)ENSG00000173598
GNOMAD BrowserENSG00000173598
Varsome BrowserNUDT4
Genetic variants : HAPMAP11163
Genomic Variants (DGV)NUDT4 [DGVbeta]
DECIPHERNUDT4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNUDT4 
Mutations
ICGC Data PortalNUDT4 
TCGA Data PortalNUDT4 
Broad Tumor PortalNUDT4
OASIS PortalNUDT4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUDT4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNUDT4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NUDT4
DgiDB (Drug Gene Interaction Database)NUDT4
DoCM (Curated mutations)NUDT4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NUDT4 (select a term)
intoGenNUDT4
Cancer3DNUDT4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609229   
Orphanet
DisGeNETNUDT4
MedgenNUDT4
Genetic Testing Registry NUDT4
NextProtQ9NZJ9 [Medical]
TSGene11163
GENETestsNUDT4
Target ValidationNUDT4
Huge Navigator NUDT4 [HugePedia]
snp3D : Map Gene to Disease11163
BioCentury BCIQNUDT4
ClinGenNUDT4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11163
Chemical/Pharm GKB GenePA31835
Clinical trialNUDT4
Miscellaneous
canSAR (ICR)NUDT4 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNUDT4
EVEXNUDT4
GoPubMedNUDT4
iHOPNUDT4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Jul 30 14:20:36 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.