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NUGGC (nuclear GTPase, germinal center associated)

Identity

Alias (NCBI)C8orf80
HMFN0672
SLIP-GC
SLIPGC
HGNC (Hugo) NUGGC
HGNC Alias symbHMFN0672
SLIP-GC
HGNC Alias namespeckled-like pattern in the germinal center
HGNC Previous nameC8orf80
HGNC Previous namechromosome 8 open reading frame 80
LocusID (NCBI) 389643
Atlas_Id 71038
Location 8p21.1  [Link to chromosome band 8p21]
Location_base_pair Starts at 28021964 and ends at 28083936 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)NUGGC   33550
Cards
Entrez_Gene (NCBI)NUGGC    nuclear GTPase, germinal center associated
AliasesC8orf80; HMFN0672; SLIP-GC; SLIPGC
GeneCards (Weizmann)NUGGC
Ensembl hg19 (Hinxton)ENSG00000189233 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000189233 [Gene_View]  ENSG00000189233 [Sequence]  chr8:28021964-28083936 [Contig_View]  NUGGC [Vega]
ICGC DataPortalENSG00000189233
TCGA cBioPortalNUGGC
AceView (NCBI)NUGGC
Genatlas (Paris)NUGGC
SOURCE (Princeton)NUGGC
Genetics Home Reference (NIH)NUGGC
Genomic and cartography
GoldenPath hg38 (UCSC)NUGGC  -     chr8:28021964-28083936 -  8p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NUGGC  -     8p21.1   [Description]    (hg19-Feb_2009)
GoldenPathNUGGC - 8p21.1 [CytoView hg19]  NUGGC - 8p21.1 [CytoView hg38]
ImmunoBaseENSG00000189233
Genome Data Viewer NCBINUGGC [Mapview hg19]  
OMIM619088   
Gene and transcription
Genbank (Entrez)AA482187 AA768146 AB075870 AK129923 BU429067
RefSeq transcript (Entrez)NM_001010906
Consensus coding sequences : CCDS (NCBI)NUGGC
Gene ExpressionNUGGC [ NCBI-GEO ]   NUGGC [ EBI - ARRAY_EXPRESS ]   NUGGC [ SEEK ]   NUGGC [ MEM ]
Gene Expression Viewer (FireBrowse)NUGGC [ Firebrowse - Broad ]
GenevisibleExpression of NUGGC in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)389643
GTEX Portal (Tissue expression)NUGGC
Human Protein AtlasENSG00000189233-NUGGC [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ68CJ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ68CJ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ68CJ6
Catalytic activity : Enzyme3.6.1.- [ Enzyme-Expasy ]   3.6.1.-3.6.1.- [ IntEnz-EBI ]   3.6.1.- [ BRENDA ]   3.6.1.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ68CJ6
Domains : Interpro (EBI)Dynamin_SF    P-loop_NTPase   
Domain families : Pfam (Sanger)Dynamin_N (PF00350)   
Domain families : Pfam (NCBI)pfam00350   
Conserved Domain (NCBI)NUGGC
SuperfamilyQ68CJ6
AlphaFold pdb e-kbQ68CJ6   
Human Protein Atlas [tissue]ENSG00000189233-NUGGC [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q68CJ6
IntAct (EBI)Q68CJ6
BioGRIDNUGGC
STRING (EMBL)NUGGC
ZODIACNUGGC
Ontologies - Pathways
QuickGOQ68CJ6
Ontology : AmiGOGTPase activity  GTPase activity  GTP binding  nuclear speck  regulation of nuclear cell cycle DNA replication  negative regulation of apoptotic process  cellular response to lipopolysaccharide  
Ontology : EGO-EBIGTPase activity  GTPase activity  GTP binding  nuclear speck  regulation of nuclear cell cycle DNA replication  negative regulation of apoptotic process  cellular response to lipopolysaccharide  
NDEx NetworkNUGGC
Atlas of Cancer Signalling NetworkNUGGC
Wikipedia pathwaysNUGGC
Orthology - Evolution
OrthoDB389643
GeneTree (enSembl)ENSG00000189233
Phylogenetic Trees/Animal Genes : TreeFamNUGGC
Homologs : HomoloGeneNUGGC
Homology/Alignments : Family Browser (UCSC)NUGGC
Gene fusions - Rearrangements
Fusion : QuiverNUGGC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUGGC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUGGC
dbVarNUGGC
ClinVarNUGGC
MonarchNUGGC
1000_GenomesNUGGC 
Exome Variant ServerNUGGC
GNOMAD BrowserENSG00000189233
Varsome BrowserNUGGC
ACMGNUGGC variants
VarityQ68CJ6
Genomic Variants (DGV)NUGGC [DGVbeta]
DECIPHERNUGGC [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNUGGC 
Mutations
ICGC Data PortalNUGGC 
TCGA Data PortalNUGGC 
Broad Tumor PortalNUGGC
OASIS PortalNUGGC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUGGC  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNUGGC
Mutations and Diseases : HGMDNUGGC
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNUGGC
DgiDB (Drug Gene Interaction Database)NUGGC
DoCM (Curated mutations)NUGGC
CIViC (Clinical Interpretations of Variants in Cancer)NUGGC
Cancer3DNUGGC
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM619088   
Orphanet
DisGeNETNUGGC
MedgenNUGGC
Genetic Testing Registry NUGGC
NextProtQ68CJ6 [Medical]
GENETestsNUGGC
Target ValidationNUGGC
Huge Navigator NUGGC [HugePedia]
ClinGenNUGGC
Clinical trials, drugs, therapy
MyCancerGenomeNUGGC
Protein Interactions : CTDNUGGC
Pharm GKB GenePA162380784
PharosQ68CJ6
Clinical trialNUGGC
Miscellaneous
canSAR (ICR)NUGGC
HarmonizomeNUGGC
DataMed IndexNUGGC
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNUGGC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:13:20 CEST 2021

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