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NUP107 (nucleoporin 107)

Identity

Alias_namesnucleoporin 107kDa
Alias_symbol (synonym)NUP84
Other aliasNPHS11
HGNC (Hugo) NUP107
LocusID (NCBI) 57122
Atlas_Id 54020
Location 12q15  [Link to chromosome band 12q15]
Location_base_pair Starts at 68686951 and ends at 68745814 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CNOT2 (12q15) / NUP107 (12q15)DRAM1 (12q23.2) / NUP107 (12q15)FRS2 (12q15) / NUP107 (12q15)
FTH1 (11q12.3) / NUP107 (12q15)HMGA2 (12q14.3) / NUP107 (12q15)LRRC59 (17q21.33) / NUP107 (12q15)
MDM2 (12q15) / NUP107 (12q15)NUP107 (12q15) / LGR5 (12q21.1)NUP107 (12q15) / PAPPA (9q33.1)
NUP107 (12q15) / RAP1B (12q15)NUP107 (12q15) / SHD (19p13.3)RAB3IP (12q15) / NUP107 (12q15)
SEC23A (14q21.1) / NUP107 (12q15)SLC35E3 (12q15) / NUP107 (12q15)TSFM (12q14.1) / NUP107 (12q15)
NUP107 12q15 / LGR5 12q21.1CNOT2 12q15 / NUP107 12q15DRAM1 12q23.2 / NUP107 12q15
FRS2 12q15 / NUP107 12q15HMGA2 12q14.3 / NUP107 12q15LRRC59 17q21.33 / NUP107 12q15
MDM2 12q15 / NUP107 12q15NUP107 12q15 / SHD 19p13.3RAB3IP 12q15 / NUP107 12q15
TSFM 12q14.1 / NUP107 12q15

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NUP107   29914
Cards
Entrez_Gene (NCBI)NUP107  57122  nucleoporin 107
AliasesNPHS11; NUP84
GeneCards (Weizmann)NUP107
Ensembl hg19 (Hinxton)ENSG00000111581 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111581 [Gene_View]  chr12:68686951-68745814 [Contig_View]  NUP107 [Vega]
ICGC DataPortalENSG00000111581
TCGA cBioPortalNUP107
AceView (NCBI)NUP107
Genatlas (Paris)NUP107
WikiGenes57122
SOURCE (Princeton)NUP107
Genetics Home Reference (NIH)NUP107
Genomic and cartography
GoldenPath hg38 (UCSC)NUP107  -     chr12:68686951-68745814 +  12q15   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NUP107  -     12q15   [Description]    (hg19-Feb_2009)
EnsemblNUP107 - 12q15 [CytoView hg19]  NUP107 - 12q15 [CytoView hg38]
Mapping of homologs : NCBINUP107 [Mapview hg19]  NUP107 [Mapview hg38]
OMIM607617   616730   
Gene and transcription
Genbank (Entrez)AJ295745 AK002079 AK055629 AK094183 AK302773
RefSeq transcript (Entrez)NM_001330192 NM_020401
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NUP107
Cluster EST : UnigeneHs.587722 [ NCBI ]
CGAP (NCI)Hs.587722
Alternative Splicing GalleryENSG00000111581
Gene ExpressionNUP107 [ NCBI-GEO ]   NUP107 [ EBI - ARRAY_EXPRESS ]   NUP107 [ SEEK ]   NUP107 [ MEM ]
Gene Expression Viewer (FireBrowse)NUP107 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57122
GTEX Portal (Tissue expression)NUP107
Human Protein AtlasENSG00000111581-NUP107 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP57740   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP57740  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP57740
Splice isoforms : SwissVarP57740
PhosPhoSitePlusP57740
Domains : Interpro (EBI)Nup84_Nup100   
Domain families : Pfam (Sanger)Nup84_Nup100 (PF04121)   
Domain families : Pfam (NCBI)pfam04121   
Conserved Domain (NCBI)NUP107
DMDM Disease mutations57122
Blocks (Seattle)NUP107
PDB (SRS)3CQC    3CQG    3I4R    5A9Q   
PDB (PDBSum)3CQC    3CQG    3I4R    5A9Q   
PDB (IMB)3CQC    3CQG    3I4R    5A9Q   
PDB (RSDB)3CQC    3CQG    3I4R    5A9Q   
Structural Biology KnowledgeBase3CQC    3CQG    3I4R    5A9Q   
SCOP (Structural Classification of Proteins)3CQC    3CQG    3I4R    5A9Q   
CATH (Classification of proteins structures)3CQC    3CQG    3I4R    5A9Q   
SuperfamilyP57740
Human Protein Atlas [tissue]ENSG00000111581-NUP107 [tissue]
Peptide AtlasP57740
HPRD06356
IPIIPI00028005   IPI00448974   IPI01010608   IPI01011062   IPI01009684   
Protein Interaction databases
DIP (DOE-UCLA)P57740
IntAct (EBI)P57740
FunCoupENSG00000111581
BioGRIDNUP107
STRING (EMBL)NUP107
ZODIACNUP107
Ontologies - Pathways
QuickGOP57740
Ontology : AmiGOkinetochore  condensed chromosome kinetochore  posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery  nucleocytoplasmic transporter activity  protein binding  nuclear envelope  nuclear pore  nucleoplasm  centrosome  cytosol  regulation of transcription, DNA-templated  mRNA export from nucleus  mRNA export from nucleus  tRNA export from nucleus  protein import into nucleus  sister chromatid cohesion  mitotic nuclear envelope disassembly  female gonad development  regulation of glucose transport  membrane  viral process  protein sumoylation  structural constituent of nuclear pore  viral transcription  gene silencing by RNA  nuclear pore outer ring  nuclear pore outer ring  nuclear membrane  nuclear periphery  nuclear pore complex assembly  intracellular transport of virus  regulation of cellular response to heat  
Ontology : EGO-EBIkinetochore  condensed chromosome kinetochore  posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery  nucleocytoplasmic transporter activity  protein binding  nuclear envelope  nuclear pore  nucleoplasm  centrosome  cytosol  regulation of transcription, DNA-templated  mRNA export from nucleus  mRNA export from nucleus  tRNA export from nucleus  protein import into nucleus  sister chromatid cohesion  mitotic nuclear envelope disassembly  female gonad development  regulation of glucose transport  membrane  viral process  protein sumoylation  structural constituent of nuclear pore  viral transcription  gene silencing by RNA  nuclear pore outer ring  nuclear pore outer ring  nuclear membrane  nuclear periphery  nuclear pore complex assembly  intracellular transport of virus  regulation of cellular response to heat  
Pathways : KEGGRNA transport   
NDEx NetworkNUP107
Atlas of Cancer Signalling NetworkNUP107
Wikipedia pathwaysNUP107
Orthology - Evolution
OrthoDB57122
GeneTree (enSembl)ENSG00000111581
Phylogenetic Trees/Animal Genes : TreeFamNUP107
HOVERGENP57740
HOGENOMP57740
Homologs : HomoloGeneNUP107
Homology/Alignments : Family Browser (UCSC)NUP107
Gene fusions - Rearrangements
Fusion : MitelmanDRAM1/NUP107 [12q23.2/12q15]  [t(12;12)(q15;q23)]  
Fusion : MitelmanHMGA2/NUP107 [12q14.3/12q15]  [t(12;12)(q14;q15)]  
Fusion : MitelmanLRRC59/NUP107 [17q21.33/12q15]  [t(12;17)(q15;q21)]  
Fusion : MitelmanNUP107/LGR5 [12q15/12q21.1]  [t(12;12)(q15;q21)]  
Fusion : MitelmanNUP107/PAPPA [12q15/9q33.1]  [t(9;12)(q33;q15)]  
Fusion : MitelmanNUP107/SHD [12q15/19p13.3]  [t(12;19)(q15;p13)]  
Fusion : MitelmanTSFM/NUP107 [12q14.1/12q15]  [t(12;12)(q14;q15)]  
Fusion: TCGA_MDACCCNOT2 12q15 NUP107 12q15 BRCA
Fusion: TCGA_MDACCDRAM1 12q23.2 NUP107 12q15 BLCA
Fusion: TCGA_MDACCFRS2 12q15 NUP107 12q15 BLCA
Fusion: TCGA_MDACCHMGA2 12q14.3 NUP107 12q15 GBM
Fusion: TCGA_MDACCLRRC59 17q21.33 NUP107 12q15 BRCA
Fusion: TCGA_MDACCMDM2 12q15 NUP107 12q15 LUAD
Fusion: TCGA_MDACCNUP107 12q15 SHD 19p13.3 LUAD
Fusion: TCGA_MDACCRAB3IP 12q15 NUP107 12q15 BLCA
Fusion: TCGA_MDACCTSFM 12q14.1 NUP107 12q15 GBM
Tumor Fusion PortalNUP107
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUP107 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUP107
dbVarNUP107
ClinVarNUP107
1000_GenomesNUP107 
Exome Variant ServerNUP107
ExAC (Exome Aggregation Consortium)ENSG00000111581
GNOMAD BrowserENSG00000111581
Genetic variants : HAPMAP57122
Genomic Variants (DGV)NUP107 [DGVbeta]
DECIPHERNUP107 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNUP107 
Mutations
ICGC Data PortalNUP107 
TCGA Data PortalNUP107 
Broad Tumor PortalNUP107
OASIS PortalNUP107 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUP107  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNUP107
intOGen PortalNUP107
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NUP107
DgiDB (Drug Gene Interaction Database)NUP107
DoCM (Curated mutations)NUP107 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NUP107 (select a term)
intoGenNUP107
Cancer3DNUP107(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607617    616730   
Orphanet1011    12191   
DisGeNETNUP107
MedgenNUP107
Genetic Testing Registry NUP107
NextProtP57740 [Medical]
TSGene57122
GENETestsNUP107
Target ValidationNUP107
Huge Navigator NUP107 [HugePedia]
snp3D : Map Gene to Disease57122
BioCentury BCIQNUP107
ClinGenNUP107
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57122
Chemical/Pharm GKB GenePA134890486
Clinical trialNUP107
Miscellaneous
canSAR (ICR)NUP107 (select the gene name)
Probes
Litterature
PubMed57 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNUP107
EVEXNUP107
GoPubMedNUP107
iHOPNUP107
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:26:59 CET 2017

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