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NUP153 (nucleoporin 153kDa)

Identity

Alias_namesnucleoporin 153kDa
Alias_symbol (synonym)HNUP153
Other aliasN153
HGNC (Hugo) NUP153
LocusID (NCBI) 9972
Atlas_Id 46894
Location 6p22.3  [Link to chromosome band 6p22]
Location_base_pair Starts at 17615266 and ends at 17707065 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
NUP153 (6p22.3) / C3orf67 (3p14.2)NUP153 (6p22.3) / GCNT2 (6p24.3)NUP153 (6p22.3) / NEDD9 (6p24.2)
NUP153 (6p22.3) / NTNG2 (9q34.13)NUP153 (6p22.3) / NUP153 (6p22.3)NUP153 (6p22.3) / RNF2 (1q25.3)
NUP153 (6p22.3) / ZNF280C (Xq26.1)NUP153 6p22.3 / GCNT2 6p24.3NUP153 6p22.3 / NEDD9 6p24.2
NUP153 6p22.3 / RNF2 1q25.3NUP153 6p22.3 / ZNF280C Xq26.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NUP153   8062
Cards
Entrez_Gene (NCBI)NUP153  9972  nucleoporin 153kDa
AliasesHNUP153; N153
GeneCards (Weizmann)NUP153
Ensembl hg19 (Hinxton)ENSG00000124789 [Gene_View]  chr6:17615266-17707065 [Contig_View]  NUP153 [Vega]
Ensembl hg38 (Hinxton)ENSG00000124789 [Gene_View]  chr6:17615266-17707065 [Contig_View]  NUP153 [Vega]
ICGC DataPortalENSG00000124789
TCGA cBioPortalNUP153
AceView (NCBI)NUP153
Genatlas (Paris)NUP153
WikiGenes9972
SOURCE (Princeton)NUP153
Genetics Home Reference (NIH)NUP153
Genomic and cartography
GoldenPath hg19 (UCSC)NUP153  -     chr6:17615266-17707065 -  6p22.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NUP153  -     6p22.3   [Description]    (hg38-Dec_2013)
EnsemblNUP153 - 6p22.3 [CytoView hg19]  NUP153 - 6p22.3 [CytoView hg38]
Mapping of homologs : NCBINUP153 [Mapview hg19]  NUP153 [Mapview hg38]
OMIM603948   
Gene and transcription
Genbank (Entrez)AB210024 AI948895 AK295644 AL597150 AW269393
RefSeq transcript (Entrez)NM_001278209 NM_001278210 NM_005124
RefSeq genomic (Entrez)NC_000006 NC_018917 NT_007592 NW_004929326
Consensus coding sequences : CCDS (NCBI)NUP153
Cluster EST : UnigeneHs.601591 [ NCBI ]
CGAP (NCI)Hs.601591
Alternative Splicing GalleryENSG00000124789
Gene ExpressionNUP153 [ NCBI-GEO ]   NUP153 [ EBI - ARRAY_EXPRESS ]   NUP153 [ SEEK ]   NUP153 [ MEM ]
Gene Expression Viewer (FireBrowse)NUP153 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9972
GTEX Portal (Tissue expression)NUP153
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49790   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49790  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49790
Splice isoforms : SwissVarP49790
PhosPhoSitePlusP49790
Domaine pattern : Prosite (Expaxy)ZF_RANBP2_1 (PS01358)    ZF_RANBP2_2 (PS50199)   
Domains : Interpro (EBI)Nup153_N    Retro-transposon_transp_CS    Znf_RanBP2   
Domain families : Pfam (Sanger)Nup153 (PF08604)    Nup_retrotrp_bd (PF10599)    zf-RanBP (PF00641)   
Domain families : Pfam (NCBI)pfam08604    pfam10599    pfam00641   
Domain families : Smart (EMBL)ZnF_RBZ (SM00547)  
Conserved Domain (NCBI)NUP153
DMDM Disease mutations9972
Blocks (Seattle)NUP153
PDB (SRS)2EBQ    2EBR    2EBV    2GQE    4U0C    4U0D   
PDB (PDBSum)2EBQ    2EBR    2EBV    2GQE    4U0C    4U0D   
PDB (IMB)2EBQ    2EBR    2EBV    2GQE    4U0C    4U0D   
PDB (RSDB)2EBQ    2EBR    2EBV    2GQE    4U0C    4U0D   
Structural Biology KnowledgeBase2EBQ    2EBR    2EBV    2GQE    4U0C    4U0D   
SCOP (Structural Classification of Proteins)2EBQ    2EBR    2EBV    2GQE    4U0C    4U0D   
CATH (Classification of proteins structures)2EBQ    2EBR    2EBV    2GQE    4U0C    4U0D   
SuperfamilyP49790
Human Protein AtlasENSG00000124789
Peptide AtlasP49790
HPRD04899
IPIIPI00292059   IPI00910194   IPI01015047   IPI00743364   
Protein Interaction databases
DIP (DOE-UCLA)P49790
IntAct (EBI)P49790
FunCoupENSG00000124789
BioGRIDNUP153
STRING (EMBL)NUP153
ZODIACNUP153
Ontologies - Pathways
QuickGOP49790
Ontology : AmiGOchromatin binding  double-stranded DNA binding  nucleocytoplasmic transporter activity  protein binding  annulate lamellae  nuclear pore  nucleoplasm  nucleolus  cytoplasm  mRNA export from nucleus  tRNA export from nucleus  mitotic nuclear division  mitotic nuclear envelope disassembly  nuclear localization sequence binding  zinc ion binding  Ran GTPase binding  regulation of glucose transport  protein transport  viral process  protein sumoylation  structural constituent of nuclear pore  viral transcription  gene silencing by RNA  nuclear membrane  nuclear periphery  nuclear inclusion body  identical protein binding  protein anchor  nuclear pore nuclear basket  viral entry into host cell  negative regulation of RNA export from nucleus  nuclear pore complex assembly  viral penetration into host nucleus  intracellular transport of virus  regulation of cellular response to heat  
Ontology : EGO-EBIchromatin binding  double-stranded DNA binding  nucleocytoplasmic transporter activity  protein binding  annulate lamellae  nuclear pore  nucleoplasm  nucleolus  cytoplasm  mRNA export from nucleus  tRNA export from nucleus  mitotic nuclear division  mitotic nuclear envelope disassembly  nuclear localization sequence binding  zinc ion binding  Ran GTPase binding  regulation of glucose transport  protein transport  viral process  protein sumoylation  structural constituent of nuclear pore  viral transcription  gene silencing by RNA  nuclear membrane  nuclear periphery  nuclear inclusion body  identical protein binding  protein anchor  nuclear pore nuclear basket  viral entry into host cell  negative regulation of RNA export from nucleus  nuclear pore complex assembly  viral penetration into host nucleus  intracellular transport of virus  regulation of cellular response to heat  
Pathways : BIOCARTAMechanism of Protein Import into the Nucleus [Genes]   
Pathways : KEGGRNA transport   
NDEx NetworkNUP153
Atlas of Cancer Signalling NetworkNUP153
Wikipedia pathwaysNUP153
Orthology - Evolution
OrthoDB9972
GeneTree (enSembl)ENSG00000124789
Phylogenetic Trees/Animal Genes : TreeFamNUP153
HOVERGENP49790
HOGENOMP49790
Homologs : HomoloGeneNUP153
Homology/Alignments : Family Browser (UCSC)NUP153
Gene fusions - Rearrangements
Fusion : MitelmanNUP153/C3orf67 [6p22.3/3p14.2]  
Fusion : MitelmanNUP153/GCNT2 [6p22.3/6p24.3]  [t(6;6)(p22;p24)]  
Fusion : MitelmanNUP153/NEDD9 [6p22.3/6p24.2]  [t(6;6)(p22;p24)]  
Fusion : MitelmanNUP153/NTNG2 [6p22.3/9q34.13]  [t(6;9)(p22;q34)]  
Fusion : MitelmanNUP153/RNF2 [6p22.3/1q25.3]  [t(1;6)(q25;p22)]  
Fusion : MitelmanNUP153/ZNF280C [6p22.3/Xq26.1]  [t(X;6)(q26;p22)]  
Fusion: TCGANUP153 6p22.3 GCNT2 6p24.3 BRCA
Fusion: TCGANUP153 6p22.3 NEDD9 6p24.2 BRCA
Fusion: TCGANUP153 6p22.3 RNF2 1q25.3 BRCA
Fusion: TCGANUP153 6p22.3 ZNF280C Xq26.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUP153 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUP153
dbVarNUP153
ClinVarNUP153
1000_GenomesNUP153 
Exome Variant ServerNUP153
ExAC (Exome Aggregation Consortium)NUP153 (select the gene name)
Genetic variants : HAPMAP9972
Genomic Variants (DGV)NUP153 [DGVbeta]
DECIPHER (Syndromes)6:17615266-17707065  ENSG00000124789
CONAN: Copy Number AnalysisNUP153 
Mutations
ICGC Data PortalNUP153 
TCGA Data PortalNUP153 
Broad Tumor PortalNUP153
OASIS PortalNUP153 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUP153  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNUP153
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NUP153
DgiDB (Drug Gene Interaction Database)NUP153
DoCM (Curated mutations)NUP153 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NUP153 (select a term)
intoGenNUP153
Cancer3DNUP153(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603948   
Orphanet
MedgenNUP153
Genetic Testing Registry NUP153
NextProtP49790 [Medical]
TSGene9972
GENETestsNUP153
Huge Navigator NUP153 [HugePedia]
snp3D : Map Gene to Disease9972
BioCentury BCIQNUP153
ClinGenNUP153
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9972
Chemical/Pharm GKB GenePA31848
Clinical trialNUP153
Miscellaneous
canSAR (ICR)NUP153 (select the gene name)
Probes
Litterature
PubMed126 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNUP153
EVEXNUP153
GoPubMedNUP153
iHOPNUP153
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:19:36 CET 2017

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