Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NUP188 (nucleoporin 188kDa)

Identity

Alias_namesKIAA0169
KIAA0169
nucleoporin 188kDa
Other aliashNup188
HGNC (Hugo) NUP188
LocusID (NCBI) 23511
Atlas_Id 71040
Location 9q34.11  [Link to chromosome band 9q34]
Location_base_pair Starts at 131709972 and ends at 131769375 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
FAM73B (9q34.11) / NUP188 (9q34.11)MAPK10 (4q21.3) / NUP188 (9q34.11)NUP188 (9q34.11) / ASTN2 (9q33.1)
NUP188 (9q34.11) / NUP188 (9q34.11)NUP188 (9q34.11) / PCNP (3q12.3)NUP188 (9q34.11) / PHYHD1 (9q34.11)
NUP188 (9q34.11) / POLR2A (17p13.1)PPP2R4 (9q34.11) / NUP188 (9q34.11)NUP188 ASTN2
NUP188 PHYHD1FAM73B NUP188PPP2R4 NUP188

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NUP188   17859
Cards
Entrez_Gene (NCBI)NUP188  23511  nucleoporin 188kDa
AliasesKIAA0169; hNup188
GeneCards (Weizmann)NUP188
Ensembl hg19 (Hinxton)ENSG00000095319 [Gene_View]  chr9:131709972-131769375 [Contig_View]  NUP188 [Vega]
Ensembl hg38 (Hinxton)ENSG00000095319 [Gene_View]  chr9:131709972-131769375 [Contig_View]  NUP188 [Vega]
ICGC DataPortalENSG00000095319
TCGA cBioPortalNUP188
AceView (NCBI)NUP188
Genatlas (Paris)NUP188
WikiGenes23511
SOURCE (Princeton)NUP188
Genetics Home Reference (NIH)NUP188
Genomic and cartography
GoldenPath hg19 (UCSC)NUP188  -     chr9:131709972-131769375 +  9q34.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NUP188  -     9q34.11   [Description]    (hg38-Dec_2013)
EnsemblNUP188 - 9q34.11 [CytoView hg19]  NUP188 - 9q34.11 [CytoView hg38]
Mapping of homologs : NCBINUP188 [Mapview hg19]  NUP188 [Mapview hg38]
OMIM615587   
Gene and transcription
Genbank (Entrez)AA731883 AK025292 BC005407 BC040352 BC111045
RefSeq transcript (Entrez)NM_015354
RefSeq genomic (Entrez)NC_000009 NC_018920 NG_033111 NT_008470 NW_004929366
Consensus coding sequences : CCDS (NCBI)NUP188
Cluster EST : UnigeneHs.308340 [ NCBI ]
CGAP (NCI)Hs.308340
Alternative Splicing GalleryENSG00000095319
Gene ExpressionNUP188 [ NCBI-GEO ]   NUP188 [ EBI - ARRAY_EXPRESS ]   NUP188 [ SEEK ]   NUP188 [ MEM ]
Gene Expression Viewer (FireBrowse)NUP188 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23511
GTEX Portal (Tissue expression)NUP188
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5SRE5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5SRE5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5SRE5
Splice isoforms : SwissVarQ5SRE5
PhosPhoSitePlusQ5SRE5
Domains : Interpro (EBI)ARM-type_fold    Nucleoporin_Nup188   
Domain families : Pfam (Sanger)Nup188 (PF10487)   
Domain families : Pfam (NCBI)pfam10487   
Conserved Domain (NCBI)NUP188
DMDM Disease mutations23511
Blocks (Seattle)NUP188
SuperfamilyQ5SRE5
Human Protein AtlasENSG00000095319
Peptide AtlasQ5SRE5
HPRD18582
IPIIPI00477040   IPI00385001   IPI00386622   IPI01026433   IPI00856092   
Protein Interaction databases
DIP (DOE-UCLA)Q5SRE5
IntAct (EBI)Q5SRE5
FunCoupENSG00000095319
BioGRIDNUP188
STRING (EMBL)NUP188
ZODIACNUP188
Ontologies - Pathways
QuickGOQ5SRE5
Ontology : AmiGOmitotic cell cycle  nuclear envelope  nuclear pore  carbohydrate metabolic process  mitotic nuclear envelope disassembly  hexose transport  gene expression  regulation of glucose transport  protein transport  glucose transport  membrane  viral process  protein sumoylation  viral life cycle  viral transcription  cytokine-mediated signaling pathway  cellular response to heat  post-translational protein modification  cellular protein metabolic process  small molecule metabolic process  mRNA transport  transmembrane transport  regulation of cellular response to heat  
Ontology : EGO-EBImitotic cell cycle  nuclear envelope  nuclear pore  carbohydrate metabolic process  mitotic nuclear envelope disassembly  hexose transport  gene expression  regulation of glucose transport  protein transport  glucose transport  membrane  viral process  protein sumoylation  viral life cycle  viral transcription  cytokine-mediated signaling pathway  cellular response to heat  post-translational protein modification  cellular protein metabolic process  small molecule metabolic process  mRNA transport  transmembrane transport  regulation of cellular response to heat  
Pathways : KEGGRNA transport   
NDEx NetworkNUP188
Atlas of Cancer Signalling NetworkNUP188
Wikipedia pathwaysNUP188
Orthology - Evolution
OrthoDB23511
GeneTree (enSembl)ENSG00000095319
Phylogenetic Trees/Animal Genes : TreeFamNUP188
HOVERGENQ5SRE5
HOGENOMQ5SRE5
Homologs : HomoloGeneNUP188
Homology/Alignments : Family Browser (UCSC)NUP188
Gene fusions - Rearrangements
Fusion: TCGANUP188 ASTN2
Fusion: TCGANUP188 PHYHD1
Fusion: TCGAFAM73B NUP188
Fusion: TCGAPPP2R4 NUP188
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUP188 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUP188
dbVarNUP188
ClinVarNUP188
1000_GenomesNUP188 
Exome Variant ServerNUP188
ExAC (Exome Aggregation Consortium)NUP188 (select the gene name)
Genetic variants : HAPMAP23511
Genomic Variants (DGV)NUP188 [DGVbeta]
DECIPHER (Syndromes)9:131709972-131769375  ENSG00000095319
CONAN: Copy Number AnalysisNUP188 
Mutations
ICGC Data PortalNUP188 
TCGA Data PortalNUP188 
Broad Tumor PortalNUP188
OASIS PortalNUP188 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUP188  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNUP188
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NUP188
DgiDB (Drug Gene Interaction Database)NUP188
DoCM (Curated mutations)NUP188 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NUP188 (select a term)
intoGenNUP188
Cancer3DNUP188(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615587   
Orphanet
MedgenNUP188
Genetic Testing Registry NUP188
NextProtQ5SRE5 [Medical]
TSGene23511
GENETestsNUP188
Huge Navigator NUP188 [HugePedia]
snp3D : Map Gene to Disease23511
BioCentury BCIQNUP188
ClinGenNUP188
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23511
Chemical/Pharm GKB GenePA134908952
Clinical trialNUP188
Miscellaneous
canSAR (ICR)NUP188 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNUP188
EVEXNUP188
GoPubMedNUP188
iHOPNUP188
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:35:36 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.