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NUP58 (nucleoporin 58)

Identity

Alias_namesNUPL1
nucleoporin like 1
nucleoporin 58kDa
Alias_symbol (synonym)KIAA0410
NUP45
Other aliasPRO2463
HGNC (Hugo) NUP58
LocusID (NCBI) 9818
Atlas_Id 77729
Location 13q12.13  [Link to chromosome band 13q12]
Location_base_pair Starts at 25301528 and ends at 25342423 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MALAT1 (11q13.1) / NUP58 (13q12.13)NUP58 (13q12.13) / CCDC169 (13q13.3)NUP58 (13q12.13) / NUP58 (13q12.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NUP58   20261
Cards
Entrez_Gene (NCBI)NUP58  9818  nucleoporin 58
AliasesNUP45; NUPL1; PRO2463
GeneCards (Weizmann)NUP58
Ensembl hg19 (Hinxton)ENSG00000139496 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139496 [Gene_View]  chr13:25301528-25342423 [Contig_View]  NUP58 [Vega]
ICGC DataPortalENSG00000139496
TCGA cBioPortalNUP58
AceView (NCBI)NUP58
Genatlas (Paris)NUP58
WikiGenes9818
SOURCE (Princeton)NUP58
Genetics Home Reference (NIH)NUP58
Genomic and cartography
GoldenPath hg38 (UCSC)NUP58  -     chr13:25301528-25342423 +  13q12.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NUP58  -     13q12.13   [Description]    (hg19-Feb_2009)
EnsemblNUP58 - 13q12.13 [CytoView hg19]  NUP58 - 13q12.13 [CytoView hg38]
Mapping of homologs : NCBINUP58 [Mapview hg19]  NUP58 [Mapview hg38]
OMIM607615   
Gene and transcription
Genbank (Entrez)AB007870 AF113020 AK025800 AK026604 AK123955
RefSeq transcript (Entrez)NM_001008564 NM_001008565 NM_014089
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NUP58
Cluster EST : UnigeneHs.732064 [ NCBI ]
CGAP (NCI)Hs.732064
Alternative Splicing GalleryENSG00000139496
Gene ExpressionNUP58 [ NCBI-GEO ]   NUP58 [ EBI - ARRAY_EXPRESS ]   NUP58 [ SEEK ]   NUP58 [ MEM ]
Gene Expression Viewer (FireBrowse)NUP58 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9818
GTEX Portal (Tissue expression)NUP58
Human Protein AtlasENSG00000139496-NUP58 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BVL2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BVL2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BVL2
Splice isoforms : SwissVarQ9BVL2
PhosPhoSitePlusQ9BVL2
Domains : Interpro (EBI)Nucleoporin_p58/p45   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)NUP58
DMDM Disease mutations9818
Blocks (Seattle)NUP58
PDB (SRS)4JO7    4JO9    4JQ5    5IJN    5IJO   
PDB (PDBSum)4JO7    4JO9    4JQ5    5IJN    5IJO   
PDB (IMB)4JO7    4JO9    4JQ5    5IJN    5IJO   
PDB (RSDB)4JO7    4JO9    4JQ5    5IJN    5IJO   
Structural Biology KnowledgeBase4JO7    4JO9    4JQ5    5IJN    5IJO   
SCOP (Structural Classification of Proteins)4JO7    4JO9    4JQ5    5IJN    5IJO   
CATH (Classification of proteins structures)4JO7    4JO9    4JQ5    5IJN    5IJO   
SuperfamilyQ9BVL2
Human Protein Atlas [tissue]ENSG00000139496-NUP58 [tissue]
Peptide AtlasQ9BVL2
HPRD06355
IPIIPI00107122   IPI00938163   IPI01010970   IPI00910174   IPI00156037   IPI00550771   IPI01018863   IPI00946361   IPI00946034   
Protein Interaction databases
DIP (DOE-UCLA)Q9BVL2
IntAct (EBI)Q9BVL2
FunCoupENSG00000139496
BioGRIDNUP58
STRING (EMBL)NUP58
ZODIACNUP58
Ontologies - Pathways
QuickGOQ9BVL2
Ontology : AmiGOnucleocytoplasmic transporter activity  protein binding  nuclear envelope  nuclear pore  mRNA export from nucleus  tRNA export from nucleus  protein import into nucleus  mitotic nuclear envelope disassembly  nuclear localization sequence binding  regulation of glucose transport  viral process  protein sumoylation  viral transcription  gene silencing by RNA  nuclear membrane  regulation of protein import into nucleus  protein homooligomerization  protein heterotetramerization  protein heterotrimerization  intracellular transport of virus  regulation of cellular response to heat  
Ontology : EGO-EBInucleocytoplasmic transporter activity  protein binding  nuclear envelope  nuclear pore  mRNA export from nucleus  tRNA export from nucleus  protein import into nucleus  matotig Nuclear envelope disassembly  nuclear localization sequence binding  regulation of glucose transport  viral process  protein sumoylation  viral transcription  gene silencing by RNA  nuclear membrane  regulation of protein import into nucleus  protein homooligomerization  protein heterotetramerization  protein heterotrimerization  intracellular transport of virus  regulation of cellular response to heat  
NDEx NetworkNUP58
Atlas of Cancer Signalling NetworkNUP58
Wikipedia pathwaysNUP58
Orthology - Evolution
OrthoDB9818
GeneTree (enSembl)ENSG00000139496
Phylogenetic Trees/Animal Genes : TreeFamNUP58
HOVERGENQ9BVL2
HOGENOMQ9BVL2
Homologs : HomoloGeneNUP58
Homology/Alignments : Family Browser (UCSC)NUP58
Gene fusions - Rearrangements
Fusion: Tumor Portal NUP58
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUP58 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUP58
dbVarNUP58
ClinVarNUP58
1000_GenomesNUP58 
Exome Variant ServerNUP58
ExAC (Exome Aggregation Consortium)ENSG00000139496
GNOMAD BrowserENSG00000139496
Genetic variants : HAPMAP9818
Genomic Variants (DGV)NUP58 [DGVbeta]
DECIPHERNUP58 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNUP58 
Mutations
ICGC Data PortalNUP58 
TCGA Data PortalNUP58 
Broad Tumor PortalNUP58
OASIS PortalNUP58 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDNUP58
BioMutasearch NUP58
DgiDB (Drug Gene Interaction Database)NUP58
DoCM (Curated mutations)NUP58 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NUP58 (select a term)
intoGenNUP58
Cancer3DNUP58(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607615   
Orphanet
MedgenNUP58
Genetic Testing Registry NUP58
NextProtQ9BVL2 [Medical]
TSGene9818
GENETestsNUP58
Target ValidationNUP58
Huge Navigator NUP58 [HugePedia]
snp3D : Map Gene to Disease9818
BioCentury BCIQNUP58
ClinGenNUP58
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9818
Chemical/Pharm GKB GenePA134981903
Clinical trialNUP58
Miscellaneous
canSAR (ICR)NUP58 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNUP58
EVEXNUP58
GoPubMedNUP58
iHOPNUP58
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:19:38 CET 2017

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