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NUP85 (nucleoporin 85)

Identity

Alias_namesnucleoporin 85kDa
Alias_symbol (synonym)NUP75
FLJ12549
Other aliasFROUNT
Nup75
HGNC (Hugo) NUP85
LocusID (NCBI) 79902
Atlas_Id 71049
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 75205450 and ends at 75235759 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MYO15B (17q25.1) / NUP85 (17q25.1)NUP85 (17q25.1) / GPC3 (Xq26.2)NUP85 (17q25.1) / KCTD2 (17q25.1)
NUP85 (17q25.1) / NUP85 (17q25.1)NUP85 (17q25.1) / SUMO2 (17q25.1)NUP85 (17q25.1) / ZDHHC18 (1p36.11)
PPM1D (17q23.2) / NUP85 (17q25.1)TMEM94 (17q25.1) / NUP85 (17q25.1)WBP2 (17q25.1) / NUP85 (17q25.1)
ZNF77 (19p13.3) / NUP85 (17q25.1)NUP85 ZDHHC18NUP85 KCTD2
PPM1D NUP85KIAA0195 NUP85

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NUP85   8734
Cards
Entrez_Gene (NCBI)NUP85  79902  nucleoporin 85
AliasesFROUNT; Nup75
GeneCards (Weizmann)NUP85
Ensembl hg19 (Hinxton)ENSG00000125450 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125450 [Gene_View]  chr17:75205450-75235759 [Contig_View]  NUP85 [Vega]
ICGC DataPortalENSG00000125450
TCGA cBioPortalNUP85
AceView (NCBI)NUP85
Genatlas (Paris)NUP85
WikiGenes79902
SOURCE (Princeton)NUP85
Genetics Home Reference (NIH)NUP85
Genomic and cartography
GoldenPath hg38 (UCSC)NUP85  -     chr17:75205450-75235759 +  17q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NUP85  -     17q25.1   [Description]    (hg19-Feb_2009)
EnsemblNUP85 - 17q25.1 [CytoView hg19]  NUP85 - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBINUP85 [Mapview hg19]  NUP85 [Mapview hg38]
OMIM170285   
Gene and transcription
Genbank (Entrez)AF498261 AF514995 AK022611 AK124501 AK295694
RefSeq transcript (Entrez)NM_001303276 NM_001330472 NM_024844
RefSeq genomic (Entrez)Consensus coding sequences : CCDS (NCBI)NUP85
Cluster EST : UnigeneHs.362817 [ NCBI ]
CGAP (NCI)Hs.362817
Alternative Splicing GalleryENSG00000125450
Gene ExpressionNUP85 [ NCBI-GEO ]   NUP85 [ EBI - ARRAY_EXPRESS ]   NUP85 [ SEEK ]   NUP85 [ MEM ]
Gene Expression Viewer (FireBrowse)NUP85 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79902
GTEX Portal (Tissue expression)NUP85
Human Protein AtlasENSG00000125450-NUP85 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BW27   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BW27  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BW27
Splice isoforms : SwissVarQ9BW27
PhosPhoSitePlusQ9BW27
Domains : Interpro (EBI)Nucleoporin_Nup85   
Domain families : Pfam (Sanger)Nucleopor_Nup85 (PF07575)   
Domain families : Pfam (NCBI)pfam07575   
Conserved Domain (NCBI)NUP85
DMDM Disease mutations79902
Blocks (Seattle)NUP85
PDB (SRS)5A9Q   
PDB (PDBSum)5A9Q   
PDB (IMB)5A9Q   
PDB (RSDB)5A9Q   
Structural Biology KnowledgeBase5A9Q   
SCOP (Structural Classification of Proteins)5A9Q   
CATH (Classification of proteins structures)5A9Q   
SuperfamilyQ9BW27
Human Protein Atlas [tissue]ENSG00000125450-NUP85 [tissue]
Peptide AtlasQ9BW27
HPRD01363
IPIIPI00790530   IPI01014661   IPI00909193   IPI00909272   IPI01013027   IPI00888760   
Protein Interaction databases
DIP (DOE-UCLA)Q9BW27
IntAct (EBI)Q9BW27
FunCoupENSG00000125450
BioGRIDNUP85
STRING (EMBL)NUP85
ZODIACNUP85
Ontologies - Pathways
QuickGOQ9BW27
Ontology : AmiGOkinetochore  condensed chromosome kinetochore  protein binding  nucleus  nuclear envelope  spindle  cytosol  cytosol  mRNA export from nucleus  mRNA export from nucleus  tRNA export from nucleus  protein import into nucleus  sister chromatid cohesion  mitotic nuclear envelope disassembly  regulation of glucose transport  membrane  viral process  protein sumoylation  structural constituent of nuclear pore  viral transcription  lamellipodium assembly  gene silencing by RNA  nuclear pore outer ring  nuclear pore outer ring  nuclear membrane  positive regulation of transcription, DNA-templated  macrophage chemotaxis  intracellular transport of virus  regulation of cellular response to heat  
Ontology : EGO-EBIkinetochore  condensed chromosome kinetochore  protein binding  nucleus  nuclear envelope  spindle  cytosol  cytosol  mRNA export from nucleus  mRNA export from nucleus  tRNA export from nucleus  protein import into nucleus  sister chromatid cohesion  mitotic nuclear envelope disassembly  regulation of glucose transport  membrane  viral process  protein sumoylation  structural constituent of nuclear pore  viral transcription  lamellipodium assembly  gene silencing by RNA  nuclear pore outer ring  nuclear pore outer ring  nuclear membrane  positive regulation of transcription, DNA-templated  macrophage chemotaxis  intracellular transport of virus  regulation of cellular response to heat  
Pathways : BIOCARTAProtein Kinase A at the Centrosome [Genes]   
Pathways : KEGGRNA transport   
NDEx NetworkNUP85
Atlas of Cancer Signalling NetworkNUP85
Wikipedia pathwaysNUP85
Orthology - Evolution
OrthoDB79902
GeneTree (enSembl)ENSG00000125450
Phylogenetic Trees/Animal Genes : TreeFamNUP85
HOVERGENQ9BW27
HOGENOMQ9BW27
Homologs : HomoloGeneNUP85
Homology/Alignments : Family Browser (UCSC)NUP85
Gene fusions - Rearrangements
Fusion: TCGA_MDACCNUP85 ZDHHC18
Fusion: TCGA_MDACCNUP85 KCTD2
Fusion: TCGA_MDACCPPM1D NUP85
Fusion: TCGA_MDACCKIAA0195 NUP85
Tumor Fusion PortalNUP85
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUP85 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUP85
dbVarNUP85
ClinVarNUP85
1000_GenomesNUP85 
Exome Variant ServerNUP85
ExAC (Exome Aggregation Consortium)ENSG00000125450
GNOMAD BrowserENSG00000125450
Genetic variants : HAPMAP79902
Genomic Variants (DGV)NUP85 [DGVbeta]
DECIPHERNUP85 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNUP85 
Mutations
ICGC Data PortalNUP85 
TCGA Data PortalNUP85 
Broad Tumor PortalNUP85
OASIS PortalNUP85 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUP85  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNUP85
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NUP85
DgiDB (Drug Gene Interaction Database)NUP85
DoCM (Curated mutations)NUP85 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NUP85 (select a term)
intoGenNUP85
Cancer3DNUP85(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM170285   
Orphanet
DisGeNETNUP85
MedgenNUP85
Genetic Testing Registry NUP85
NextProtQ9BW27 [Medical]
TSGene79902
GENETestsNUP85
Target ValidationNUP85
Huge Navigator NUP85 [HugePedia]
snp3D : Map Gene to Disease79902
BioCentury BCIQNUP85
ClinGenNUP85
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79902
Chemical/Pharm GKB GenePA142671241
Clinical trialNUP85
Miscellaneous
canSAR (ICR)NUP85 (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNUP85
EVEXNUP85
GoPubMedNUP85
iHOPNUP85
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:36:26 CET 2017

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