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NUP85 (nucleoporin 85kDa)

Identity

Alias_namesnucleoporin 85kDa
Alias_symbol (synonym)NUP75
FLJ12549
Other aliasFROUNT
Nup75
HGNC (Hugo) NUP85
LocusID (NCBI) 79902
Atlas_Id 71049
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 73201545 and ends at 73231854 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MYO15B (17q25.1) / NUP85 (17q25.1)NUP85 (17q25.1) / GPC3 (Xq26.2)NUP85 (17q25.1) / KCTD2 (17q25.1)
NUP85 (17q25.1) / NUP85 (17q25.1)NUP85 (17q25.1) / SUMO2 (17q25.1)NUP85 (17q25.1) / ZDHHC18 (1p36.11)
PPM1D (17q23.2) / NUP85 (17q25.1)TMEM94 (17q25.1) / NUP85 (17q25.1)WBP2 (17q25.1) / NUP85 (17q25.1)
ZNF77 (19p13.3) / NUP85 (17q25.1)NUP85 ZDHHC18NUP85 KCTD2
PPM1D NUP85KIAA0195 NUP85

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NUP85   8734
Cards
Entrez_Gene (NCBI)NUP85  79902  nucleoporin 85kDa
AliasesFROUNT; Nup75
GeneCards (Weizmann)NUP85
Ensembl hg19 (Hinxton)ENSG00000125450 [Gene_View]  chr17:73201545-73231854 [Contig_View]  NUP85 [Vega]
Ensembl hg38 (Hinxton)ENSG00000125450 [Gene_View]  chr17:73201545-73231854 [Contig_View]  NUP85 [Vega]
ICGC DataPortalENSG00000125450
TCGA cBioPortalNUP85
AceView (NCBI)NUP85
Genatlas (Paris)NUP85
WikiGenes79902
SOURCE (Princeton)NUP85
Genetics Home Reference (NIH)NUP85
Genomic and cartography
GoldenPath hg19 (UCSC)NUP85  -     chr17:73201545-73231854 +  17q25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NUP85  -     17q25.1   [Description]    (hg38-Dec_2013)
EnsemblNUP85 - 17q25.1 [CytoView hg19]  NUP85 - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBINUP85 [Mapview hg19]  NUP85 [Mapview hg38]
OMIM170285   
Gene and transcription
Genbank (Entrez)AF498261 AF514995 AK022611 AK124501 AK295694
RefSeq transcript (Entrez)NM_001303276 NM_024844
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)NUP85
Cluster EST : UnigeneHs.362817 [ NCBI ]
CGAP (NCI)Hs.362817
Alternative Splicing GalleryENSG00000125450
Gene ExpressionNUP85 [ NCBI-GEO ]   NUP85 [ EBI - ARRAY_EXPRESS ]   NUP85 [ SEEK ]   NUP85 [ MEM ]
Gene Expression Viewer (FireBrowse)NUP85 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79902
GTEX Portal (Tissue expression)NUP85
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BW27   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BW27  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BW27
Splice isoforms : SwissVarQ9BW27
PhosPhoSitePlusQ9BW27
Domains : Interpro (EBI)Nucleoporin_Nup85   
Domain families : Pfam (Sanger)Nucleopor_Nup85 (PF07575)   
Domain families : Pfam (NCBI)pfam07575   
Conserved Domain (NCBI)NUP85
DMDM Disease mutations79902
Blocks (Seattle)NUP85
SuperfamilyQ9BW27
Human Protein AtlasENSG00000125450
Peptide AtlasQ9BW27
HPRD01363
IPIIPI00790530   IPI01014661   IPI00909193   IPI00909272   IPI01013027   IPI00888760   
Protein Interaction databases
DIP (DOE-UCLA)Q9BW27
IntAct (EBI)Q9BW27
FunCoupENSG00000125450
BioGRIDNUP85
STRING (EMBL)NUP85
ZODIACNUP85
Ontologies - Pathways
QuickGOQ9BW27
Ontology : AmiGOmitotic cell cycle  kinetochore  condensed chromosome kinetochore  protein binding  nuclear envelope  spindle  cytosol  carbohydrate metabolic process  mitotic nuclear envelope disassembly  small GTPase mediated signal transduction  hexose transport  gene expression  regulation of glucose transport  protein transport  glucose transport  membrane  viral process  protein sumoylation  viral life cycle  viral transcription  cytokine-mediated signaling pathway  lamellipodium assembly  nuclear pore outer ring  nuclear pore outer ring  nuclear membrane  cellular response to heat  post-translational protein modification  cellular protein metabolic process  small molecule metabolic process  macrophage chemotaxis  mRNA transport  transmembrane transport  regulation of cellular response to heat  
Ontology : EGO-EBImitotic cell cycle  kinetochore  condensed chromosome kinetochore  protein binding  nuclear envelope  spindle  cytosol  carbohydrate metabolic process  mitotic nuclear envelope disassembly  small GTPase mediated signal transduction  hexose transport  gene expression  regulation of glucose transport  protein transport  glucose transport  membrane  viral process  protein sumoylation  viral life cycle  viral transcription  cytokine-mediated signaling pathway  lamellipodium assembly  nuclear pore outer ring  nuclear pore outer ring  nuclear membrane  cellular response to heat  post-translational protein modification  cellular protein metabolic process  small molecule metabolic process  macrophage chemotaxis  mRNA transport  transmembrane transport  regulation of cellular response to heat  
Pathways : BIOCARTAProtein Kinase A at the Centrosome [Genes]   
Pathways : KEGGRNA transport   
NDEx NetworkNUP85
Atlas of Cancer Signalling NetworkNUP85
Wikipedia pathwaysNUP85
Orthology - Evolution
OrthoDB79902
GeneTree (enSembl)ENSG00000125450
Phylogenetic Trees/Animal Genes : TreeFamNUP85
HOVERGENQ9BW27
HOGENOMQ9BW27
Homologs : HomoloGeneNUP85
Homology/Alignments : Family Browser (UCSC)NUP85
Gene fusions - Rearrangements
Fusion: TCGANUP85 ZDHHC18
Fusion: TCGANUP85 KCTD2
Fusion: TCGAPPM1D NUP85
Fusion: TCGAKIAA0195 NUP85
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUP85 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUP85
dbVarNUP85
ClinVarNUP85
1000_GenomesNUP85 
Exome Variant ServerNUP85
ExAC (Exome Aggregation Consortium)NUP85 (select the gene name)
Genetic variants : HAPMAP79902
Genomic Variants (DGV)NUP85 [DGVbeta]
DECIPHER (Syndromes)17:73201545-73231854  ENSG00000125450
CONAN: Copy Number AnalysisNUP85 
Mutations
ICGC Data PortalNUP85 
TCGA Data PortalNUP85 
Broad Tumor PortalNUP85
OASIS PortalNUP85 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUP85  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNUP85
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NUP85
DgiDB (Drug Gene Interaction Database)NUP85
DoCM (Curated mutations)NUP85 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NUP85 (select a term)
intoGenNUP85
Cancer3DNUP85(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM170285   
Orphanet
MedgenNUP85
Genetic Testing Registry NUP85
NextProtQ9BW27 [Medical]
TSGene79902
GENETestsNUP85
Huge Navigator NUP85 [HugePedia]
snp3D : Map Gene to Disease79902
BioCentury BCIQNUP85
ClinGenNUP85
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79902
Chemical/Pharm GKB GenePA142671241
Clinical trialNUP85
Miscellaneous
canSAR (ICR)NUP85 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNUP85
EVEXNUP85
GoPubMedNUP85
iHOPNUP85
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 12:35:38 CET 2017

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