Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NUP88 (nucleoporin 88)

Identity

Alias (NCBI)FADS4
HGNC (Hugo) NUP88
HGNC Alias symbMGC8530
HGNC Previous namenucleoporin 88kD
 nucleoporin 88kDa
LocusID (NCBI) 4927
Atlas_Id 41594
Location 17p13.2  [Link to chromosome band 17p13]
Location_base_pair Starts at 5384833 and ends at 5419662 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FRMD4B (3p14.1) / NUP88 (17p13.2)RABEP1 (17p13.2) / NUP88 (17p13.2)SF3B3 (16q22.1) / NUP88 (17p13.2)
VTCN1 (1p13.1) / NUP88 (17p13.2)RABEP1 17p13.2 / NUP88 17p13.2VTCN1 1p13.1 / NUP88 17p13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(5;9)(q35;q34) SQSTM1/NUP214


External links

 

Nomenclature
HGNC (Hugo)NUP88   8067
Cards
Entrez_Gene (NCBI)NUP88    nucleoporin 88
AliasesFADS4
GeneCards (Weizmann)NUP88
Ensembl hg19 (Hinxton)ENSG00000108559 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108559 [Gene_View]  ENSG00000108559 [Sequence]  chr17:5384833-5419662 [Contig_View]  NUP88 [Vega]
ICGC DataPortalENSG00000108559
TCGA cBioPortalNUP88
AceView (NCBI)NUP88
Genatlas (Paris)NUP88
SOURCE (Princeton)NUP88
Genetics Home Reference (NIH)NUP88
Genomic and cartography
GoldenPath hg38 (UCSC)NUP88  -     chr17:5384833-5419662 -  17p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NUP88  -     17p13.2   [Description]    (hg19-Feb_2009)
GoldenPathNUP88 - 17p13.2 [CytoView hg19]  NUP88 - 17p13.2 [CytoView hg38]
ImmunoBaseENSG00000108559
Genome Data Viewer NCBINUP88 [Mapview hg19]  
OMIM602552   618393   
Gene and transcription
Genbank (Entrez)AK225247 AK298158 AK299000 AK308142 AW089098
RefSeq transcript (Entrez)NM_001320653 NM_002532
Consensus coding sequences : CCDS (NCBI)NUP88
Gene ExpressionNUP88 [ NCBI-GEO ]   NUP88 [ EBI - ARRAY_EXPRESS ]   NUP88 [ SEEK ]   NUP88 [ MEM ]
Gene Expression Viewer (FireBrowse)NUP88 [ Firebrowse - Broad ]
GenevisibleExpression of NUP88 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4927
GTEX Portal (Tissue expression)NUP88
Human Protein AtlasENSG00000108559-NUP88 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99567   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99567  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99567
PhosPhoSitePlusQ99567
Domains : Interpro (EBI)Nucleoporin_Nup88    NUP88/NUP82   
Domain families : Pfam (Sanger)Nup88 (PF10168)   
Domain families : Pfam (NCBI)pfam10168   
Conserved Domain (NCBI)NUP88
SuperfamilyQ99567
AlphaFold pdb e-kbQ99567   
Human Protein Atlas [tissue]ENSG00000108559-NUP88 [tissue]
HPRD03974
Protein Interaction databases
DIP (DOE-UCLA)Q99567
IntAct (EBI)Q99567
BioGRIDNUP88
STRING (EMBL)NUP88
ZODIACNUP88
Ontologies - Pathways
QuickGOQ99567
Ontology : AmiGOribosomal large subunit export from nucleus  ribosomal small subunit export from nucleus  mitotic cell cycle  transporter activity  protein binding  nuclear pore  nuclear pore  nucleoplasm  cytosol  regulation of glycolytic process  mRNA export from nucleus  mRNA export from nucleus  tRNA export from nucleus  protein import into nucleus  viral process  protein sumoylation  structural constituent of nuclear pore  viral life cycle  viral transcription  host cell  regulation of gene silencing by miRNA  intracellular transport of virus  regulation of cellular response to heat  
Ontology : EGO-EBIribosomal large subunit export from nucleus  ribosomal small subunit export from nucleus  mitotic cell cycle  transporter activity  protein binding  nuclear pore  nuclear pore  nucleoplasm  cytosol  regulation of glycolytic process  mRNA export from nucleus  mRNA export from nucleus  tRNA export from nucleus  protein import into nucleus  viral process  protein sumoylation  structural constituent of nuclear pore  viral life cycle  viral transcription  host cell  regulation of gene silencing by miRNA  intracellular transport of virus  regulation of cellular response to heat  
Pathways : KEGGRNA transport   
NDEx NetworkNUP88
Atlas of Cancer Signalling NetworkNUP88
Wikipedia pathwaysNUP88
Orthology - Evolution
OrthoDB4927
GeneTree (enSembl)ENSG00000108559
Phylogenetic Trees/Animal Genes : TreeFamNUP88
Homologs : HomoloGeneNUP88
Homology/Alignments : Family Browser (UCSC)NUP88
Gene fusions - Rearrangements
Fusion : MitelmanRABEP1/NUP88 [17p13.2/17p13.2]  
Fusion : MitelmanVTCN1/NUP88 [1p13.1/17p13.2]  
Fusion : QuiverNUP88
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUP88 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUP88
dbVarNUP88
ClinVarNUP88
MonarchNUP88
1000_GenomesNUP88 
Exome Variant ServerNUP88
GNOMAD BrowserENSG00000108559
Varsome BrowserNUP88
ACMGNUP88 variants
VarityQ99567
Genomic Variants (DGV)NUP88 [DGVbeta]
DECIPHERNUP88 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNUP88 
Mutations
ICGC Data PortalNUP88 
TCGA Data PortalNUP88 
Broad Tumor PortalNUP88
OASIS PortalNUP88 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUP88  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNUP88
Mutations and Diseases : HGMDNUP88
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNUP88
DgiDB (Drug Gene Interaction Database)NUP88
DoCM (Curated mutations)NUP88
CIViC (Clinical Interpretations of Variants in Cancer)NUP88
Cancer3DNUP88
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602552    618393   
Orphanet
DisGeNETNUP88
MedgenNUP88
Genetic Testing Registry NUP88
NextProtQ99567 [Medical]
GENETestsNUP88
Target ValidationNUP88
Huge Navigator NUP88 [HugePedia]
ClinGenNUP88
Clinical trials, drugs, therapy
MyCancerGenomeNUP88
Protein Interactions : CTDNUP88
Pharm GKB GenePA31855
PharosQ99567
Clinical trialNUP88
Miscellaneous
canSAR (ICR)NUP88
HarmonizomeNUP88
DataMed IndexNUP88
Probes
Litterature
PubMed87 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNUP88
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:23:34 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.