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NUP88 (nucleoporin 88)

Identity

Alias_namesnucleoporin 88kD
nucleoporin 88kDa
Alias_symbol (synonym)MGC8530
Other alias-
HGNC (Hugo) NUP88
LocusID (NCBI) 4927
Atlas_Id 41594
Location 17p13.2  [Link to chromosome band 17p13]
Location_base_pair Starts at 5384833 and ends at 5419739 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FRMD4B (3p14.1) / NUP88 (17p13.2)RABEP1 (17p13.2) / NUP88 (17p13.2)SF3B3 (16q22.1) / NUP88 (17p13.2)
VTCN1 (1p13.1) / NUP88 (17p13.2)RABEP1 17p13.2 / NUP88 17p13.2VTCN1 1p13.1 / NUP88 17p13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NUP88   8067
Cards
Entrez_Gene (NCBI)NUP88  4927  nucleoporin 88
Aliases
GeneCards (Weizmann)NUP88
Ensembl hg19 (Hinxton)ENSG00000108559 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108559 [Gene_View]  chr17:5384833-5419739 [Contig_View]  NUP88 [Vega]
ICGC DataPortalENSG00000108559
TCGA cBioPortalNUP88
AceView (NCBI)NUP88
Genatlas (Paris)NUP88
WikiGenes4927
SOURCE (Princeton)NUP88
Genetics Home Reference (NIH)NUP88
Genomic and cartography
GoldenPath hg38 (UCSC)NUP88  -     chr17:5384833-5419739 -  17p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NUP88  -     17p13.2   [Description]    (hg19-Feb_2009)
EnsemblNUP88 - 17p13.2 [CytoView hg19]  NUP88 - 17p13.2 [CytoView hg38]
Mapping of homologs : NCBINUP88 [Mapview hg19]  NUP88 [Mapview hg38]
OMIM602552   
Gene and transcription
Genbank (Entrez)AK225247 AK298158 AK299000 AK308142 AW089098
RefSeq transcript (Entrez)NM_001320653 NM_002532
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NUP88
Cluster EST : UnigeneHs.733301 [ NCBI ]
CGAP (NCI)Hs.733301
Alternative Splicing GalleryENSG00000108559
Gene ExpressionNUP88 [ NCBI-GEO ]   NUP88 [ EBI - ARRAY_EXPRESS ]   NUP88 [ SEEK ]   NUP88 [ MEM ]
Gene Expression Viewer (FireBrowse)NUP88 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4927
GTEX Portal (Tissue expression)NUP88
Human Protein AtlasENSG00000108559-NUP88 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99567   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99567  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99567
Splice isoforms : SwissVarQ99567
PhosPhoSitePlusQ99567
Domains : Interpro (EBI)Nucleoporin_Nup88   
Domain families : Pfam (Sanger)Nup88 (PF10168)   
Domain families : Pfam (NCBI)pfam10168   
Conserved Domain (NCBI)NUP88
DMDM Disease mutations4927
Blocks (Seattle)NUP88
SuperfamilyQ99567
Human Protein Atlas [tissue]ENSG00000108559-NUP88 [tissue]
Peptide AtlasQ99567
HPRD03974
IPIIPI00001738   IPI01011969   
Protein Interaction databases
DIP (DOE-UCLA)Q99567
IntAct (EBI)Q99567
FunCoupENSG00000108559
BioGRIDNUP88
STRING (EMBL)NUP88
ZODIACNUP88
Ontologies - Pathways
QuickGOQ99567
Ontology : AmiGOribosomal large subunit export from nucleus  ribosomal small subunit export from nucleus  transporter activity  nuclear pore  nucleoplasm  cytosol  mRNA export from nucleus  mRNA export from nucleus  tRNA export from nucleus  protein import into nucleus  protein export from nucleus  mitotic nuclear envelope disassembly  regulation of glucose transport  viral process  protein sumoylation  viral transcription  gene silencing by RNA  intracellular transport of virus  regulation of cellular response to heat  
Ontology : EGO-EBIribosomal large subunit export from nucleus  ribosomal small subunit export from nucleus  transporter activity  nuclear pore  nucleoplasm  cytosol  mRNA export from nucleus  mRNA export from nucleus  tRNA export from nucleus  protein import into nucleus  protein export from nucleus  mitotic nuclear envelope disassembly  regulation of glucose transport  viral process  protein sumoylation  viral transcription  gene silencing by RNA  intracellular transport of virus  regulation of cellular response to heat  
Pathways : KEGGRNA transport   
NDEx NetworkNUP88
Atlas of Cancer Signalling NetworkNUP88
Wikipedia pathwaysNUP88
Orthology - Evolution
OrthoDB4927
GeneTree (enSembl)ENSG00000108559
Phylogenetic Trees/Animal Genes : TreeFamNUP88
HOVERGENQ99567
HOGENOMQ99567
Homologs : HomoloGeneNUP88
Homology/Alignments : Family Browser (UCSC)NUP88
Gene fusions - Rearrangements
Fusion : MitelmanRABEP1/NUP88 [17p13.2/17p13.2]  [t(17;17)(p13;p13)]  
Fusion : MitelmanVTCN1/NUP88 [1p13.1/17p13.2]  [t(1;17)(p13;p13)]  
Fusion: TCGA_MDACCRABEP1 17p13.2 NUP88 17p13.2 BRCA
Fusion: TCGA_MDACCVTCN1 1p13.1 NUP88 17p13.2 BRCA
Tumor Fusion PortalNUP88
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUP88 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUP88
dbVarNUP88
ClinVarNUP88
1000_GenomesNUP88 
Exome Variant ServerNUP88
ExAC (Exome Aggregation Consortium)ENSG00000108559
GNOMAD BrowserENSG00000108559
Genetic variants : HAPMAP4927
Genomic Variants (DGV)NUP88 [DGVbeta]
DECIPHERNUP88 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNUP88 
Mutations
ICGC Data PortalNUP88 
TCGA Data PortalNUP88 
Broad Tumor PortalNUP88
OASIS PortalNUP88 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUP88  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNUP88
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NUP88
DgiDB (Drug Gene Interaction Database)NUP88
DoCM (Curated mutations)NUP88 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NUP88 (select a term)
intoGenNUP88
Cancer3DNUP88(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602552   
Orphanet
DisGeNETNUP88
MedgenNUP88
Genetic Testing Registry NUP88
NextProtQ99567 [Medical]
TSGene4927
GENETestsNUP88
Target ValidationNUP88
Huge Navigator NUP88 [HugePedia]
snp3D : Map Gene to Disease4927
BioCentury BCIQNUP88
ClinGenNUP88
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4927
Chemical/Pharm GKB GenePA31855
Clinical trialNUP88
Miscellaneous
canSAR (ICR)NUP88 (select the gene name)
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNUP88
EVEXNUP88
GoPubMedNUP88
iHOPNUP88
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:27:01 CET 2017

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