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NUS1 (NUS1 dehydrodolichyl diphosphate synthase subunit)

Identity

Alias (NCBI)C6orf68
CDG1AA
MGC:7199
MRD55
NgBR
TANGO14
HGNC (Hugo) NUS1
HGNC Alias symbMGC7199
NgBR
TANGO14
HGNC Alias nameNogo-B receptor
 transport and golgi organization 14 homolog (Drosophila)
HGNC Previous nameC6orf68
HGNC Previous namechromosome 6 open reading frame 68
 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
LocusID (NCBI) 116150
Atlas_Id 54853
Location 6q22.1  [Link to chromosome band 6q22]
Location_base_pair Starts at 117675469 and ends at 117710723 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)NUS1   21042
Cards
Entrez_Gene (NCBI)NUS1    NUS1 dehydrodolichyl diphosphate synthase subunit
AliasesC6orf68; CDG1AA; MGC:7199; MRD55; 
NgBR; TANGO14
GeneCards (Weizmann)NUS1
Ensembl hg19 (Hinxton)ENSG00000153989 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000153989 [Gene_View]  ENSG00000153989 [Sequence]  chr6:117675469-117710723 [Contig_View]  NUS1 [Vega]
ICGC DataPortalENSG00000153989
TCGA cBioPortalNUS1
AceView (NCBI)NUS1
Genatlas (Paris)NUS1
SOURCE (Princeton)NUS1
Genetics Home Reference (NIH)NUS1
Genomic and cartography
GoldenPath hg38 (UCSC)NUS1  -     chr6:117675469-117710723 +  6q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NUS1  -     6q22.1   [Description]    (hg19-Feb_2009)
GoldenPathNUS1 - 6q22.1 [CytoView hg19]  NUS1 - 6q22.1 [CytoView hg38]
ImmunoBaseENSG00000153989
Genome Data Viewer NCBINUS1 [Mapview hg19]  
OMIM610463   617082   617831   
Gene and transcription
Genbank (Entrez)AA825565 AJ420576 AK025467 AK125119 AK126335
RefSeq transcript (Entrez)NM_138459
Consensus coding sequences : CCDS (NCBI)NUS1
Gene ExpressionNUS1 [ NCBI-GEO ]   NUS1 [ EBI - ARRAY_EXPRESS ]   NUS1 [ SEEK ]   NUS1 [ MEM ]
Gene Expression Viewer (FireBrowse)NUS1 [ Firebrowse - Broad ]
GenevisibleExpression of NUS1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)116150
GTEX Portal (Tissue expression)NUS1
Human Protein AtlasENSG00000153989-NUS1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96E22   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96E22  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96E22
PhosPhoSitePlusQ96E22
Domains : Interpro (EBI)Nus1/NgBR    UPP_synth-like    UPP_synth-like_sf   
Domain families : Pfam (Sanger)Prenyltransf (PF01255)   
Domain families : Pfam (NCBI)pfam01255   
Conserved Domain (NCBI)NUS1
PDB (RSDB)6W2L    6Z1N   
PDB Europe6W2L    6Z1N   
PDB (PDBSum)6W2L    6Z1N   
PDB (IMB)6W2L    6Z1N   
Structural Biology KnowledgeBase6W2L    6Z1N   
SCOP (Structural Classification of Proteins)6W2L    6Z1N   
CATH (Classification of proteins structures)6W2L    6Z1N   
SuperfamilyQ96E22
AlphaFold pdb e-kbQ96E22   
Human Protein Atlas [tissue]ENSG00000153989-NUS1 [tissue]
HPRD12894
Protein Interaction databases
DIP (DOE-UCLA)Q96E22
IntAct (EBI)Q96E22
BioGRIDNUS1
STRING (EMBL)NUS1
ZODIACNUS1
Ontologies - Pathways
QuickGOQ96E22
Ontology : AmiGOangiogenesis  prenyltransferase activity  protein binding  endoplasmic reticulum membrane  endoplasmic reticulum membrane  endoplasmic reticulum membrane  protein glycosylation  dolichyl diphosphate biosynthetic process  dolichyl diphosphate biosynthetic process  integral component of membrane  dolichol biosynthetic process  dolichol biosynthetic process  cell differentiation  regulation of intracellular cholesterol transport  protein mannosylation  vascular endothelial growth factor signaling pathway  cholesterol homeostasis  positive regulation of blood vessel endothelial cell migration  dehydrodolichyl diphosphate synthase activity  metal ion binding  positive regulation of nitric-oxide synthase activity  dehydrodolichyl diphosphate synthase complex  dehydrodolichyl diphosphate synthase complex  
Ontology : EGO-EBIangiogenesis  prenyltransferase activity  protein binding  endoplasmic reticulum membrane  endoplasmic reticulum membrane  endoplasmic reticulum membrane  protein glycosylation  dolichyl diphosphate biosynthetic process  dolichyl diphosphate biosynthetic process  integral component of membrane  dolichol biosynthetic process  dolichol biosynthetic process  cell differentiation  regulation of intracellular cholesterol transport  protein mannosylation  vascular endothelial growth factor signaling pathway  cholesterol homeostasis  positive regulation of blood vessel endothelial cell migration  dehydrodolichyl diphosphate synthase activity  metal ion binding  positive regulation of nitric-oxide synthase activity  dehydrodolichyl diphosphate synthase complex  dehydrodolichyl diphosphate synthase complex  
NDEx NetworkNUS1
Atlas of Cancer Signalling NetworkNUS1
Wikipedia pathwaysNUS1
Orthology - Evolution
OrthoDB116150
GeneTree (enSembl)ENSG00000153989
Phylogenetic Trees/Animal Genes : TreeFamNUS1
Homologs : HomoloGeneNUS1
Homology/Alignments : Family Browser (UCSC)NUS1
Gene fusions - Rearrangements
Fusion : QuiverNUS1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNUS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NUS1
dbVarNUS1
ClinVarNUS1
MonarchNUS1
1000_GenomesNUS1 
Exome Variant ServerNUS1
GNOMAD BrowserENSG00000153989
Varsome BrowserNUS1
ACMGNUS1 variants
VarityQ96E22
Genomic Variants (DGV)NUS1 [DGVbeta]
DECIPHERNUS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNUS1 
Mutations
ICGC Data PortalNUS1 
TCGA Data PortalNUS1 
Broad Tumor PortalNUS1
OASIS PortalNUS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNUS1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNUS1
Mutations and Diseases : HGMDNUS1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNUS1
DgiDB (Drug Gene Interaction Database)NUS1
DoCM (Curated mutations)NUS1
CIViC (Clinical Interpretations of Variants in Cancer)NUS1
Cancer3DNUS1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610463    617082    617831   
Orphanet
DisGeNETNUS1
MedgenNUS1
Genetic Testing Registry NUS1
NextProtQ96E22 [Medical]
GENETestsNUS1
Target ValidationNUS1
Huge Navigator NUS1 [HugePedia]
ClinGenNUS1
Clinical trials, drugs, therapy
MyCancerGenomeNUS1
Protein Interactions : CTDNUS1
Pharm GKB GenePA162398248
PharosQ96E22
Clinical trialNUS1
Miscellaneous
canSAR (ICR)NUS1
HarmonizomeNUS1
DataMed IndexNUS1
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNUS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:23:34 CEST 2021

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