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NXF2 (nuclear RNA export factor 2)

Identity

Alias_symbol (synonym)CT39
TAPL-2
Other aliasTCP11X2
HGNC (Hugo) NXF2
LocusID (NCBI) 56001
Atlas_Id 54996
Location Xq22.1  [Link to chromosome band Xq22]
Location_base_pair Starts at 102247100 and ends at 102326720 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NXF2   8072
Cards
Entrez_Gene (NCBI)NXF2  56001  nuclear RNA export factor 2
AliasesCT39; TAPL-2; TCP11X2
GeneCards (Weizmann)NXF2
Ensembl hg19 (Hinxton)ENSG00000269405 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000269405 [Gene_View]  chrX:102247100-102326720 [Contig_View]  NXF2 [Vega]
ICGC DataPortalENSG00000269405
TCGA cBioPortalNXF2
AceView (NCBI)NXF2
Genatlas (Paris)NXF2
WikiGenes56001
SOURCE (Princeton)NXF2
Genetics Home Reference (NIH)NXF2
Genomic and cartography
GoldenPath hg38 (UCSC)NXF2  -     chrX:102247100-102326720 +  Xq22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NXF2  -     Xq22.1   [Description]    (hg19-Feb_2009)
EnsemblNXF2 - Xq22.1 [CytoView hg19]  NXF2 - Xq22.1 [CytoView hg38]
Mapping of homologs : NCBINXF2 [Mapview hg19]  NXF2 [Mapview hg38]
OMIM300315   
Gene and transcription
Genbank (Entrez)AF285596 AJ277659 AK000423 AK303069 AK308255
RefSeq transcript (Entrez)NM_001039910 NM_017809 NM_022053
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NXF2
Cluster EST : UnigeneHs.737538 [ NCBI ]
CGAP (NCI)Hs.737538
Alternative Splicing GalleryENSG00000269405
Gene ExpressionNXF2 [ NCBI-GEO ]   NXF2 [ EBI - ARRAY_EXPRESS ]   NXF2 [ SEEK ]   NXF2 [ MEM ]
Gene Expression Viewer (FireBrowse)NXF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56001
GTEX Portal (Tissue expression)NXF2
Human Protein AtlasENSG00000269405-NXF2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZY0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZY0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZY0
Splice isoforms : SwissVarQ9GZY0
PhosPhoSitePlusQ9GZY0
Domaine pattern : Prosite (Expaxy)LRR (PS51450)    NTF2_DOMAIN (PS50177)    TAP_C (PS51281)   
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt    NTF2    NTF2-like_dom    Nuclear_transport_factor_2_euk    Nucleotide-bd_a/b_plait    NXF5    NXF_fam    RRM_dom    TAP_C_dom    Tap_RNA-bd    UBA-like   
Domain families : Pfam (Sanger)NTF2 (PF02136)    Tap-RNA_bind (PF09162)    TAP_C (PF03943)   
Domain families : Pfam (NCBI)pfam02136    pfam09162    pfam03943   
Domain families : Smart (EMBL)TAP_C (SM00804)  
Domain structure : Prodom (Prabi Lyon)Tap_RNA_bd (PD043466)   
Conserved Domain (NCBI)NXF2
DMDM Disease mutations56001
Blocks (Seattle)NXF2
SuperfamilyQ9GZY0
Human Protein Atlas [tissue]ENSG00000269405-NXF2 [tissue]
Peptide AtlasQ9GZY0
HPRD02260
IPIIPI00004931   IPI00909769   IPI00646021   IPI00888099   
Protein Interaction databases
DIP (DOE-UCLA)Q9GZY0
IntAct (EBI)Q9GZY0
FunCoupENSG00000269405
BioGRIDNXF2
STRING (EMBL)NXF2
ZODIACNXF2
Ontologies - Pathways
QuickGOQ9GZY0
Ontology : AmiGORNA binding  protein binding  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  RNA export from nucleus  mRNA export from nucleus  mRNA export from nucleus  multicellular organism development  poly(A)+ mRNA export from nucleus  nuclear RNA export factor complex  RNA transport  
Ontology : EGO-EBIRNA binding  protein binding  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  RNA export from nucleus  mRNA export from nucleus  mRNA export from nucleus  multicellular organism development  poly(A)+ mRNA export from nucleus  nuclear RNA export factor complex  RNA transport  
Pathways : KEGGRibosome biogenesis in eukaryotes    RNA transport    mRNA surveillance pathway    Influenza A    Herpes simplex infection   
NDEx NetworkNXF2
Atlas of Cancer Signalling NetworkNXF2
Wikipedia pathwaysNXF2
Orthology - Evolution
OrthoDB56001
GeneTree (enSembl)ENSG00000269405
Phylogenetic Trees/Animal Genes : TreeFamNXF2
HOVERGENQ9GZY0
HOGENOMQ9GZY0
Homologs : HomoloGeneNXF2
Homology/Alignments : Family Browser (UCSC)NXF2
Gene fusions - Rearrangements
Tumor Fusion PortalNXF2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNXF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NXF2
dbVarNXF2
ClinVarNXF2
1000_GenomesNXF2 
Exome Variant ServerNXF2
ExAC (Exome Aggregation Consortium)ENSG00000269405
GNOMAD BrowserENSG00000269405
Genetic variants : HAPMAP56001
Genomic Variants (DGV)NXF2 [DGVbeta]
DECIPHERNXF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNXF2 
Mutations
ICGC Data PortalNXF2 
TCGA Data PortalNXF2 
Broad Tumor PortalNXF2
OASIS PortalNXF2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDNXF2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NXF2
DgiDB (Drug Gene Interaction Database)NXF2
DoCM (Curated mutations)NXF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NXF2 (select a term)
intoGenNXF2
Cancer3DNXF2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300315   
Orphanet
DisGeNETNXF2
MedgenNXF2
Genetic Testing Registry NXF2
NextProtQ9GZY0 [Medical]
TSGene56001
GENETestsNXF2
Target ValidationNXF2
Huge Navigator NXF2 [HugePedia]
snp3D : Map Gene to Disease56001
BioCentury BCIQNXF2
ClinGenNXF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56001
Chemical/Pharm GKB GenePA31859
Clinical trialNXF2
Miscellaneous
canSAR (ICR)NXF2 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNXF2
EVEXNXF2
GoPubMedNXF2
iHOPNXF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:27:04 CET 2017

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