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NXF2 (nuclear RNA export factor 2)

Identity

Alias (NCBI)CT39
TAPL-2
TCP11X2
HGNC (Hugo) NXF2
HGNC Alias symbCT39
TAPL-2
HGNC Alias namecancer/testis antigen 39
 TAP like protein 2
LocusID (NCBI) 56001
Atlas_Id 54996
Location Xq22.1  [Link to chromosome band Xq22]
Location_base_pair Starts at 102247167 and ends at 102326722 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)NXF2   8072
Cards
Entrez_Gene (NCBI)NXF2    nuclear RNA export factor 2
AliasesCT39; TAPL-2; TCP11X2
GeneCards (Weizmann)NXF2
Ensembl hg19 (Hinxton)ENSG00000269405 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000269405 [Gene_View]  ENSG00000269405 [Sequence]  chrX:102247167-102326722 [Contig_View]  NXF2 [Vega]
ICGC DataPortalENSG00000269405
TCGA cBioPortalNXF2
AceView (NCBI)NXF2
Genatlas (Paris)NXF2
SOURCE (Princeton)NXF2
Genetics Home Reference (NIH)NXF2
Genomic and cartography
GoldenPath hg38 (UCSC)NXF2  -     chrX:102247167-102326722 +  Xq22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NXF2  -     Xq22.1   [Description]    (hg19-Feb_2009)
GoldenPathNXF2 - Xq22.1 [CytoView hg19]  NXF2 - Xq22.1 [CytoView hg38]
ImmunoBaseENSG00000269405
Genome Data Viewer NCBINXF2 [Mapview hg19]  
OMIM300315   
Gene and transcription
Genbank (Entrez)AF285596 AJ277659 AK000423 AK303069 AK308255
RefSeq transcript (Entrez)NM_001039910 NM_017809 NM_022053
Consensus coding sequences : CCDS (NCBI)NXF2
Gene ExpressionNXF2 [ NCBI-GEO ]   NXF2 [ EBI - ARRAY_EXPRESS ]   NXF2 [ SEEK ]   NXF2 [ MEM ]
Gene Expression Viewer (FireBrowse)NXF2 [ Firebrowse - Broad ]
GenevisibleExpression of NXF2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56001
GTEX Portal (Tissue expression)NXF2
Human Protein AtlasENSG00000269405-NXF2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZY0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZY0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZY0
PhosPhoSitePlusQ9GZY0
Domaine pattern : Prosite (Expaxy)LRR (PS51450)    NTF2_DOMAIN (PS50177)    TAP_C (PS51281)   
Domains : Interpro (EBI)Leu-rich_rpt    LRR_dom_sf    NTF2    NTF2-like_dom_sf    Nuclear_transport_factor_2_euk    Nucleotide-bd_a/b_plait_sf    NXF5    NXF_fam    RBD_domain_sf    TAP_C_dom    Tap_RNA-bd    UBA-like_sf   
Domain families : Pfam (Sanger)NTF2 (PF02136)    Tap-RNA_bind (PF09162)    TAP_C (PF03943)   
Domain families : Pfam (NCBI)pfam02136    pfam09162    pfam03943   
Domain families : Smart (EMBL)TAP_C (SM00804)  
Conserved Domain (NCBI)NXF2
SuperfamilyQ9GZY0
AlphaFold pdb e-kbQ9GZY0   
Human Protein Atlas [tissue]ENSG00000269405-NXF2 [tissue]
HPRD02260
Protein Interaction databases
DIP (DOE-UCLA)Q9GZY0
IntAct (EBI)Q9GZY0
BioGRIDNXF2
STRING (EMBL)NXF2
ZODIACNXF2
Ontologies - Pathways
QuickGOQ9GZY0
Ontology : AmiGORNA binding  RNA binding  protein binding  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  mRNA export from nucleus  mRNA export from nucleus  multicellular organism development  poly(A)+ mRNA export from nucleus  nuclear RNA export factor complex  RNA transport  
Ontology : EGO-EBIRNA binding  RNA binding  protein binding  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  mRNA export from nucleus  mRNA export from nucleus  multicellular organism development  poly(A)+ mRNA export from nucleus  nuclear RNA export factor complex  RNA transport  
Pathways : KEGGRibosome biogenesis in eukaryotes    RNA transport    mRNA surveillance pathway    Influenza A    Herpes simplex infection   
NDEx NetworkNXF2
Atlas of Cancer Signalling NetworkNXF2
Wikipedia pathwaysNXF2
Orthology - Evolution
OrthoDB56001
GeneTree (enSembl)ENSG00000269405
Phylogenetic Trees/Animal Genes : TreeFamNXF2
Homologs : HomoloGeneNXF2
Homology/Alignments : Family Browser (UCSC)NXF2
Gene fusions - Rearrangements
Fusion : QuiverNXF2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNXF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NXF2
dbVarNXF2
ClinVarNXF2
MonarchNXF2
1000_GenomesNXF2 
Exome Variant ServerNXF2
GNOMAD BrowserENSG00000269405
Varsome BrowserNXF2
ACMGNXF2 variants
VarityQ9GZY0
Genomic Variants (DGV)NXF2 [DGVbeta]
DECIPHERNXF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNXF2 
Mutations
ICGC Data PortalNXF2 
TCGA Data PortalNXF2 
Broad Tumor PortalNXF2
OASIS PortalNXF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNXF2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNXF2
Mutations and Diseases : HGMDNXF2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNXF2
DgiDB (Drug Gene Interaction Database)NXF2
DoCM (Curated mutations)NXF2
CIViC (Clinical Interpretations of Variants in Cancer)NXF2
Cancer3DNXF2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300315   
Orphanet
DisGeNETNXF2
MedgenNXF2
Genetic Testing Registry NXF2
NextProtQ9GZY0 [Medical]
GENETestsNXF2
Target ValidationNXF2
Huge Navigator NXF2 [HugePedia]
ClinGenNXF2
Clinical trials, drugs, therapy
MyCancerGenomeNXF2
Protein Interactions : CTDNXF2
Pharm GKB GenePA31859
PharosQ9GZY0
Clinical trialNXF2
Miscellaneous
canSAR (ICR)NXF2
HarmonizomeNXF2
DataMed IndexNXF2
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNXF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:23:36 CEST 2021

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