NXT1 (nuclear transport factor 2 like export factor 1)

2014-11-01  

Identity

HGNC
LOCATION
20p11.21
LOCUSID
ALIAS
MTR2,P15
FUSION GENES

Other Information

Locus ID:

NCBI: 29107
MIM: 605811
HGNC: 15913
Ensembl: ENSG00000132661

Variants:

dbSNP: 29107
ClinVar: 29107
TCGA: ENSG00000132661
COSMIC: NXT1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132661ENST00000254998Q9UKK6

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
RNA transportKEGGko03013
RNA transportKEGGhsa03013
mRNA surveillance pathwayKEGGko03015
mRNA surveillance pathwayKEGGhsa03015
Ribosome biogenesis in eukaryotesKEGGko03008
Ribosome biogenesis in eukaryotesKEGGhsa03008
Influenza AKEGGko05164
Influenza AKEGGhsa05164
Exon junction complex (EJC)KEGGhsa_M00430
Exon junction complex (EJC)KEGGM00430
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
Transport of Mature Transcript to CytoplasmREACTOMER-HSA-72202
Transport of Mature mRNA derived from an Intron-Containing TranscriptREACTOMER-HSA-159236

References

Pubmed IDYearTitleCitations
256283612015The principal mRNA nuclear export factor NXF1:NXT1 forms a symmetric binding platform that facilitates export of retroviral CTE-RNA.15
274833022016NXT1, a Novel Influenza A NP Binding Protein, Promotes the Nuclear Export of NP via a CRM1-Dependent Pathway.6

Citation

Dessen P

NXT1 (nuclear transport factor 2 like export factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71073/nxt1