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ODC1 (ornithine decarboxylase 1)

Identity

Alias_symbol (synonym)ODC
Other alias
HGNC (Hugo) ODC1
LocusID (NCBI) 4953
Atlas_Id 41603
Location 2p25.1  [Link to chromosome band 2p25]
Location_base_pair Starts at 10580497 and ends at 10588680 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
KITLG (12q21.32) / ODC1 (2p25.1)ODC1 (2p25.1) / ODC1 (2p25.1)PPP3CB (10q22.2) / ODC1 (2p25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ODC1   8109
Cards
Entrez_Gene (NCBI)ODC1  4953  ornithine decarboxylase 1
AliasesODC
GeneCards (Weizmann)ODC1
Ensembl hg19 (Hinxton)ENSG00000115758 [Gene_View]  chr2:10580497-10588680 [Contig_View]  ODC1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000115758 [Gene_View]  chr2:10580497-10588680 [Contig_View]  ODC1 [Vega]
ICGC DataPortalENSG00000115758
TCGA cBioPortalODC1
AceView (NCBI)ODC1
Genatlas (Paris)ODC1
WikiGenes4953
SOURCE (Princeton)ODC1
Genetics Home Reference (NIH)ODC1
Genomic and cartography
GoldenPath hg19 (UCSC)ODC1  -     chr2:10580497-10588680 -  2p25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ODC1  -     2p25.1   [Description]    (hg38-Dec_2013)
EnsemblODC1 - 2p25.1 [CytoView hg19]  ODC1 - 2p25.1 [CytoView hg38]
Mapping of homologs : NCBIODC1 [Mapview hg19]  ODC1 [Mapview hg38]
OMIM165640   
Gene and transcription
Genbank (Entrez)AB362578 AI277727 AK292352 AK301956 AK312766
RefSeq transcript (Entrez)NM_001287188 NM_001287189 NM_001287190 NM_002539
RefSeq genomic (Entrez)NC_000002 NC_018913 NG_012105 NT_005334 NW_004929298
Consensus coding sequences : CCDS (NCBI)ODC1
Cluster EST : UnigeneHs.467701 [ NCBI ]
CGAP (NCI)Hs.467701
Alternative Splicing GalleryENSG00000115758
Gene ExpressionODC1 [ NCBI-GEO ]   ODC1 [ EBI - ARRAY_EXPRESS ]   ODC1 [ SEEK ]   ODC1 [ MEM ]
Gene Expression Viewer (FireBrowse)ODC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4953
GTEX Portal (Tissue expression)ODC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP11926   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP11926  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP11926
Splice isoforms : SwissVarP11926
PhosPhoSitePlusP11926
Domaine pattern : Prosite (Expaxy)ODR_DC_2_1 (PS00878)    ODR_DC_2_2 (PS00879)   
Domains : Interpro (EBI)Ala_racemase/Decarboxylase_C    De-COase2_C    De-COase2_CS    De-COase2_N    De-COase2_pyr-phos_BS    Orn/DAP/Arg_de-COase    Orn_de-COase    PLP-binding_barrel   
Domain families : Pfam (Sanger)Orn_Arg_deC_N (PF02784)    Orn_DAP_Arg_deC (PF00278)   
Domain families : Pfam (NCBI)pfam02784    pfam00278   
Conserved Domain (NCBI)ODC1
DMDM Disease mutations4953
Blocks (Seattle)ODC1
PDB (SRS)1D7K    2ON3    2OO0    4ZGY    5BWA   
PDB (PDBSum)1D7K    2ON3    2OO0    4ZGY    5BWA   
PDB (IMB)1D7K    2ON3    2OO0    4ZGY    5BWA   
PDB (RSDB)1D7K    2ON3    2OO0    4ZGY    5BWA   
Structural Biology KnowledgeBase1D7K    2ON3    2OO0    4ZGY    5BWA   
SCOP (Structural Classification of Proteins)1D7K    2ON3    2OO0    4ZGY    5BWA   
CATH (Classification of proteins structures)1D7K    2ON3    2OO0    4ZGY    5BWA   
SuperfamilyP11926
Human Protein AtlasENSG00000115758
Peptide AtlasP11926
HPRD01324
IPIIPI00008497   IPI01014956   IPI00893027   
Protein Interaction databases
DIP (DOE-UCLA)P11926
IntAct (EBI)P11926
FunCoupENSG00000115758
BioGRIDODC1
STRING (EMBL)ODC1
ZODIACODC1
Ontologies - Pathways
QuickGOP11926
Ontology : AmiGOkidney development  ornithine decarboxylase activity  ornithine decarboxylase activity  ornithine decarboxylase activity  protein binding  cellular_component  cytoplasm  cytoplasm  cytosol  regulation of cellular amino acid metabolic process  polyamine metabolic process  positive regulation of cell proliferation  response to virus  putrescine biosynthetic process from ornithine  putrescine biosynthetic process from ornithine  putrescine biosynthetic process from ornithine  regulation of protein catabolic process  protein homodimerization activity  perinuclear region of cytoplasm  
Ontology : EGO-EBIkidney development  ornithine decarboxylase activity  ornithine decarboxylase activity  ornithine decarboxylase activity  protein binding  cellular_component  cytoplasm  cytoplasm  cytosol  regulation of cellular amino acid metabolic process  polyamine metabolic process  positive regulation of cell proliferation  response to virus  putrescine biosynthetic process from ornithine  putrescine biosynthetic process from ornithine  putrescine biosynthetic process from ornithine  regulation of protein catabolic process  protein homodimerization activity  perinuclear region of cytoplasm  
Pathways : KEGGArginine and proline metabolism    Glutathione metabolism   
NDEx NetworkODC1
Atlas of Cancer Signalling NetworkODC1
Wikipedia pathwaysODC1
Orthology - Evolution
OrthoDB4953
GeneTree (enSembl)ENSG00000115758
Phylogenetic Trees/Animal Genes : TreeFamODC1
HOVERGENP11926
HOGENOMP11926
Homologs : HomoloGeneODC1
Homology/Alignments : Family Browser (UCSC)ODC1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerODC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ODC1
dbVarODC1
ClinVarODC1
1000_GenomesODC1 
Exome Variant ServerODC1
ExAC (Exome Aggregation Consortium)ODC1 (select the gene name)
Genetic variants : HAPMAP4953
Genomic Variants (DGV)ODC1 [DGVbeta]
DECIPHER (Syndromes)2:10580497-10588680  ENSG00000115758
CONAN: Copy Number AnalysisODC1 
Mutations
ICGC Data PortalODC1 
TCGA Data PortalODC1 
Broad Tumor PortalODC1
OASIS PortalODC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICODC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDODC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ODC1
DgiDB (Drug Gene Interaction Database)ODC1
DoCM (Curated mutations)ODC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ODC1 (select a term)
intoGenODC1
Cancer3DODC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM165640   
Orphanet
MedgenODC1
Genetic Testing Registry ODC1
NextProtP11926 [Medical]
TSGene4953
GENETestsODC1
Huge Navigator ODC1 [HugePedia]
snp3D : Map Gene to Disease4953
BioCentury BCIQODC1
ClinGenODC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4953
Chemical/Pharm GKB GenePA31897
Clinical trialODC1
Miscellaneous
canSAR (ICR)ODC1 (select the gene name)
Probes
Litterature
PubMed85 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineODC1
EVEXODC1
GoPubMedODC1
iHOPODC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:19:45 CET 2017

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