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OFCC1 (orofacial cleft 1 candidate 1)

Identity

Alias_symbol (synonym)MRDS1
Other aliasOpo
HGNC (Hugo) OFCC1
LocusID (NCBI) 266553
Atlas_Id 71099
Location 6p24.3  [Link to chromosome band 6p24]
Location_base_pair Starts at 9896711 and ends at 10060689 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HIVEP1 OFCC1USP36 OFCC1
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(6;6)(p24;p24) HIVEP1/OFCC1
t(6;14)(p24;q23) RHOJ/OFCC1
t(6;17)(p24;q25) USP36/OFCC1


External links

Nomenclature
HGNC (Hugo)OFCC1   21017
Cards
Entrez_Gene (NCBI)OFCC1  266553  orofacial cleft 1 candidate 1
AliasesMRDS1; Opo
GeneCards (Weizmann)OFCC1
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]   [Sequence]  chr6:9896711-10060689 [Contig_View]  OFCC1 [Vega]
TCGA cBioPortalOFCC1
AceView (NCBI)OFCC1
Genatlas (Paris)OFCC1
WikiGenes266553
SOURCE (Princeton)OFCC1
Genetics Home Reference (NIH)OFCC1
Genomic and cartography
GoldenPath hg38 (UCSC)OFCC1  -     chr6:9896711-10060689 -  6p24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OFCC1  -     6p24.3   [Description]    (hg19-Feb_2009)
EnsemblOFCC1 - 6p24.3 [CytoView hg19]  OFCC1 - 6p24.3 [CytoView hg38]
Mapping of homologs : NCBIOFCC1 [Mapview hg19]  OFCC1 [Mapview hg38]
OMIM614287   
Gene and transcription
Genbank (Entrez)AF520800 AF520801 AF520802 AF520803 AF520804
RefSeq transcript (Entrez)NM_153003
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OFCC1
Cluster EST : UnigeneHs.544715 [ NCBI ]
CGAP (NCI)Hs.544715
Gene ExpressionOFCC1 [ NCBI-GEO ]   OFCC1 [ EBI - ARRAY_EXPRESS ]   OFCC1 [ SEEK ]   OFCC1 [ MEM ]
Gene Expression Viewer (FireBrowse)OFCC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)266553
GTEX Portal (Tissue expression)OFCC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IZS5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IZS5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IZS5
Splice isoforms : SwissVarQ8IZS5
PhosPhoSitePlusQ8IZS5
Domains : Interpro (EBI)OFCC1   
Domain families : Pfam (Sanger)OFCC1 (PF15680)   
Domain families : Pfam (NCBI)pfam15680   
Conserved Domain (NCBI)OFCC1
DMDM Disease mutations266553
Blocks (Seattle)OFCC1
SuperfamilyQ8IZS5
Peptide AtlasQ8IZS5
IPIIPI00186621   IPI00218059   IPI00893262   IPI00478152   IPI00333208   IPI00984930   IPI00218060   IPI00945212   IPI00872347   IPI00946840   IPI00946076   
Protein Interaction databases
DIP (DOE-UCLA)Q8IZS5
IntAct (EBI)Q8IZS5
BioGRIDOFCC1
STRING (EMBL)OFCC1
ZODIACOFCC1
Ontologies - Pathways
QuickGOQ8IZS5
Ontology : AmiGOprotein binding  
Ontology : EGO-EBIprotein binding  
NDEx NetworkOFCC1
Atlas of Cancer Signalling NetworkOFCC1
Wikipedia pathwaysOFCC1
Orthology - Evolution
OrthoDB266553
Phylogenetic Trees/Animal Genes : TreeFamOFCC1
HOVERGENQ8IZS5
HOGENOMQ8IZS5
Homologs : HomoloGeneOFCC1
Homology/Alignments : Family Browser (UCSC)OFCC1
Gene fusions - Rearrangements
Fusion PortalHIVEP1 OFCC1
Fusion PortalUSP36 OFCC1
Fusion : QuiverOFCC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOFCC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OFCC1
dbVarOFCC1
ClinVarOFCC1
1000_GenomesOFCC1 
Exome Variant ServerOFCC1
Varsome BrowserOFCC1
Genetic variants : HAPMAP266553
Genomic Variants (DGV)OFCC1 [DGVbeta]
DECIPHEROFCC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOFCC1 
Mutations
ICGC Data PortalOFCC1 
TCGA Data PortalOFCC1 
Broad Tumor PortalOFCC1
OASIS PortalOFCC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOFCC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOFCC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OFCC1
DgiDB (Drug Gene Interaction Database)OFCC1
DoCM (Curated mutations)OFCC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OFCC1 (select a term)
intoGenOFCC1
Cancer3DOFCC1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614287   
Orphanet
DisGeNETOFCC1
MedgenOFCC1
Genetic Testing Registry OFCC1
NextProtQ8IZS5 [Medical]
TSGene266553
GENETestsOFCC1
Target ValidationOFCC1
Huge Navigator OFCC1 [HugePedia]
snp3D : Map Gene to Disease266553
BioCentury BCIQOFCC1
ClinGenOFCC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD266553
Chemical/Pharm GKB GenePA134905750
Clinical trialOFCC1
Miscellaneous
canSAR (ICR)OFCC1 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOFCC1
EVEXOFCC1
GoPubMedOFCC1
iHOPOFCC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:20:53 CEST 2018

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