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OGFOD1 (2-oxoglutarate and iron dependent oxygenase domain containing 1)

Identity

Alias (NCBI)TPA1
HGNC (Hugo) OGFOD1
HGNC Alias symbKIAA1612
FLJ10826
TPA1
HGNC Alias nameTPA1, termination and polyadenylation 1, homolog (S. cerevisiae)
HGNC Previous name2-oxoglutarate and iron-dependent oxygenase domain containing 1
LocusID (NCBI) 55239
Atlas_Id 55813
Location 16q13  [Link to chromosome band 16q13]
Location_base_pair Starts at 56451554 and ends at 56479102 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
OGFOD1 (16q12.2) / OGFOD1 (16q12.2)OGFOD1 (16q12.2) / PARP14 (3q21.1)OGFOD1 (16q12.2) / RPS18 (6p21.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)OGFOD1   25585
Cards
Entrez_Gene (NCBI)OGFOD1    2-oxoglutarate and iron dependent oxygenase domain containing 1
AliasesTPA1
GeneCards (Weizmann)OGFOD1
Ensembl hg19 (Hinxton)ENSG00000087263 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000087263 [Gene_View]  ENSG00000087263 [Sequence]  chr16:56451554-56479102 [Contig_View]  OGFOD1 [Vega]
ICGC DataPortalENSG00000087263
TCGA cBioPortalOGFOD1
AceView (NCBI)OGFOD1
Genatlas (Paris)OGFOD1
SOURCE (Princeton)OGFOD1
Genetics Home Reference (NIH)OGFOD1
Genomic and cartography
GoldenPath hg38 (UCSC)OGFOD1  -     chr16:56451554-56479102 +  16q13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OGFOD1  -     16q13   [Description]    (hg19-Feb_2009)
GoldenPathOGFOD1 - 16q13 [CytoView hg19]  OGFOD1 - 16q13 [CytoView hg38]
ImmunoBaseENSG00000087263
Genome Data Viewer NCBIOGFOD1 [Mapview hg19]  
OMIM615857   
Gene and transcription
Genbank (Entrez)AB046832 AK001688 AK022130 AK022752 AK024314
RefSeq transcript (Entrez)NM_001324357 NM_001324358 NM_001324359 NM_001324360 NM_001324361 NM_001324362 NM_001324363 NM_018233
Consensus coding sequences : CCDS (NCBI)OGFOD1
Gene ExpressionOGFOD1 [ NCBI-GEO ]   OGFOD1 [ EBI - ARRAY_EXPRESS ]   OGFOD1 [ SEEK ]   OGFOD1 [ MEM ]
Gene Expression Viewer (FireBrowse)OGFOD1 [ Firebrowse - Broad ]
GenevisibleExpression of OGFOD1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55239
GTEX Portal (Tissue expression)OGFOD1
Human Protein AtlasENSG00000087263-OGFOD1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N543   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N543  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N543
Catalytic activity : Enzyme1.14.11.- [ Enzyme-Expasy ]   1.14.11.-1.14.11.- [ IntEnz-EBI ]   1.14.11.- [ BRENDA ]   1.14.11.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ8N543
Domaine pattern : Prosite (Expaxy)FE2OG_OXY (PS51471)   
Domains : Interpro (EBI)Oxoglu/Fe-dep_dioxygenase    Oxoglutarate/Fe-dep_Oase_C    Pro_4_hyd_alph    TPA1/OFD1_N   
Domain families : Pfam (Sanger)2OG-FeII_Oxy_4 (PF13661)    Ofd1_CTDD (PF10637)   
Domain families : Pfam (NCBI)pfam13661    pfam10637   
Domain families : Smart (EMBL)P4Hc (SM00702)  
Conserved Domain (NCBI)OGFOD1
PDB (RSDB)4NHX    4NHY   
PDB Europe4NHX    4NHY   
PDB (PDBSum)4NHX    4NHY   
PDB (IMB)4NHX    4NHY   
Structural Biology KnowledgeBase4NHX    4NHY   
SCOP (Structural Classification of Proteins)4NHX    4NHY   
CATH (Classification of proteins structures)4NHX    4NHY   
SuperfamilyQ8N543
AlphaFold pdb e-kbQ8N543   
Human Protein Atlas [tissue]ENSG00000087263-OGFOD1 [tissue]
HPRD08553
Protein Interaction databases
DIP (DOE-UCLA)Q8N543
IntAct (EBI)Q8N543
BioGRIDOGFOD1
STRING (EMBL)OGFOD1
ZODIACOGFOD1
Ontologies - Pathways
QuickGOQ8N543
Ontology : AmiGOiron ion binding  protein binding  nucleoplasm  cytoplasm  cytosol  regulation of translational termination  regulation of translational termination  cell population proliferation  cytoplasmic stress granule  protein hydroxylation  peptidyl-proline hydroxylation  peptidyl-proline hydroxylation  L-ascorbic acid binding  peptidyl-proline dioxygenase activity  peptidyl-proline dioxygenase activity  peptidyl-proline 3-dioxygenase activity  stress granule assembly  
Ontology : EGO-EBIiron ion binding  protein binding  nucleoplasm  cytoplasm  cytosol  regulation of translational termination  regulation of translational termination  cell population proliferation  cytoplasmic stress granule  protein hydroxylation  peptidyl-proline hydroxylation  peptidyl-proline hydroxylation  L-ascorbic acid binding  peptidyl-proline dioxygenase activity  peptidyl-proline dioxygenase activity  peptidyl-proline 3-dioxygenase activity  stress granule assembly  
NDEx NetworkOGFOD1
Atlas of Cancer Signalling NetworkOGFOD1
Wikipedia pathwaysOGFOD1
Orthology - Evolution
OrthoDB55239
GeneTree (enSembl)ENSG00000087263
Phylogenetic Trees/Animal Genes : TreeFamOGFOD1
Homologs : HomoloGeneOGFOD1
Homology/Alignments : Family Browser (UCSC)OGFOD1
Gene fusions - Rearrangements
Fusion : QuiverOGFOD1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOGFOD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OGFOD1
dbVarOGFOD1
ClinVarOGFOD1
MonarchOGFOD1
1000_GenomesOGFOD1 
Exome Variant ServerOGFOD1
GNOMAD BrowserENSG00000087263
Varsome BrowserOGFOD1
ACMGOGFOD1 variants
VarityQ8N543
Genomic Variants (DGV)OGFOD1 [DGVbeta]
DECIPHEROGFOD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOGFOD1 
Mutations
ICGC Data PortalOGFOD1 
TCGA Data PortalOGFOD1 
Broad Tumor PortalOGFOD1
OASIS PortalOGFOD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOGFOD1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DOGFOD1
Mutations and Diseases : HGMDOGFOD1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaOGFOD1
DgiDB (Drug Gene Interaction Database)OGFOD1
DoCM (Curated mutations)OGFOD1
CIViC (Clinical Interpretations of Variants in Cancer)OGFOD1
Cancer3DOGFOD1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615857   
Orphanet
DisGeNETOGFOD1
MedgenOGFOD1
Genetic Testing Registry OGFOD1
NextProtQ8N543 [Medical]
GENETestsOGFOD1
Target ValidationOGFOD1
Huge Navigator OGFOD1 [HugePedia]
ClinGenOGFOD1
Clinical trials, drugs, therapy
MyCancerGenomeOGFOD1
Protein Interactions : CTDOGFOD1
Pharm GKB GenePA143485568
PharosQ8N543
Clinical trialOGFOD1
Miscellaneous
canSAR (ICR)OGFOD1
HarmonizomeOGFOD1
DataMed IndexOGFOD1
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXOGFOD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:23:42 CEST 2021

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