OGFOD1 (2-oxoglutarate and iron dependent oxygenase domain containing 1)

2016-06-01  

Identity

HGNC
LOCATION
16q13
LOCUSID
ALIAS
TPA1
FUSION GENES

Other Information

Locus ID:

NCBI: 55239
MIM: 615857
HGNC: 25585
Ensembl: ENSG00000087263

Variants:

dbSNP: 55239
ClinVar: 55239
TCGA: ENSG00000087263
COSMIC: OGFOD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000087263ENST00000336111J3KNR5
ENSG00000087263ENST00000561646H3BUA6
ENSG00000087263ENST00000562150H3BR79
ENSG00000087263ENST00000565682H3BR02
ENSG00000087263ENST00000566157Q8N543
ENSG00000087263ENST00000568397A0A0A0MTR2
ENSG00000087263ENST00000569802H3BP48

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
245504472014OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation.46
201541462010OGFOD1, a novel modulator of eukaryotic translation initiation factor 2alpha phosphorylation and the cellular response to stress.35
205796382010OGFOD1, a member of the 2-oxoglutarate and iron dependent dioxygenase family, functions in ischemic signaling.12
259092882015OGFOD1 is required for breast cancer cell proliferation and is associated with poor prognosis in breast cancer.1
320026292020OGFOD1 negatively regulated by miR-1224-5p promotes proliferation in human papillomavirus-infected laryngeal papillomas.0

Citation

Dessen P

OGFOD1 (2-oxoglutarate and iron dependent oxygenase domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-06-01

Online version: http://atlasgeneticsoncology.org/gene/55813/ogfod1