OGFR (opioid growth factor receptor)

2007-02-01  

Identity

HGNC
LOCATION
20q13.33
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 11054
MIM: 606459
HGNC: 15768
Ensembl: ENSG00000060491

Variants:

dbSNP: 11054
ClinVar: 11054
TCGA: ENSG00000060491
COSMIC: OGFR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000060491ENST00000290291Q9NZT2
ENSG00000060491ENST00000370461A0A0A0MRN5
ENSG00000060491ENST00000450048Q4VXW3
ENSG00000060491ENST00000621591A0A087X028

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
189231422009The OGF-OGFr axis utilizes the p16INK4a and p21WAF1/CIP1 pathways to restrict normal cell proliferation.28
196752832009Opioid growth factor-opioid growth factor receptor axis is a physiological determinant of cell proliferation in diverse human cancers.21
192975472009Cell proliferation of human ovarian cancer is regulated by the opioid growth factor-opioid growth factor receptor axis.16
199233572010The opioid growth factor-opioid growth factor receptor axis regulates cell proliferation of human hepatocellular cancer.9
192445452009Dependence on nuclear localization signals of the opioid growth factor receptor in the regulation of cell proliferation.7
198356292009Growth inhibition of thyroid follicular cell-derived cancers by the opioid growth factor (OGF) - opioid growth factor receptor (OGFr) axis.7
238569082013Targeting the opioid growth factor: opioid growth factor receptor axis for treatment of human ovarian cancer.7
186361522008Prevention and delay in progression of human pancreatic cancer by stable overexpression of the opioid growth factor receptor.6
271676862016Morphine Suppresses Lung Cancer Cell Proliferation Through the Interaction with Opioid Growth Factor Receptor: An In Vitro and Human Lung Tissue Study.6
168208932006Opioid growth factor receptor is unaltered with the progression of human pancreatic and colon cancers.4

Citation

Dessen P

OGFR (opioid growth factor receptor)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43878/ogfr