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OGT (O-linked N-acetylglucosamine (GlcNAc) transferase)

Identity

Other namesHRNT1
O-GLCNAC
HGNC (Hugo) OGT
LocusID (NCBI) 8473
Location Xq13.1
Location_base_pair Starts at 70752912 and ends at 70795747 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)OGT   8127
Entrez_Gene (NCBI)OGT  8473  O-linked N-acetylglucosamine (GlcNAc) transferase
Cards
GeneCards (Weizmann)OGT
Ensembl (Hinxton)ENSG00000147162 [Gene_View]  chrX:70752912-70795747 [Contig_View]  OGT [Vega]
AceView (NCBI)OGT
Genatlas (Paris)OGT
SOURCE (Stanford)NM_003605 NM_181672 NM_181673
Genomic and cartography
GoldenPath (UCSC)OGT  -  Xq13.1   chrX:70752912-70795747 +  Xq13.1   [Description]    (hg19-Feb_2009)
EnsemblOGT - Xq13.1 [CytoView]
Mapping of homologs : NCBIOGT [Mapview]
OMIM300255   
Gene and transcription
Genbank (Entrez)AF070560 AF147394 AF223393 AK300267 AK313530
RefSeq transcript (SRS)NM_003605 NM_181672 NM_181673
RefSeq transcript (Entrez)NM_003605 NM_181672 NM_181673
RefSeq genomic (SRS)AC_000155 NC_000023 NC_018934 NG_015875 NT_011669 NW_001842373 NW_004078123
RefSeq genomic (Entrez)AC_000155 NC_000023 NC_018934 NG_015875 NT_011669 NW_001842373 NW_004078123
Consensus coding sequences : CCDS (NCBI)OGT
Cluster EST : UnigeneHs.405410 [ SRS ] Hs.405410 [ NCBI ]
CGAP (NCI)Hs.405410
Alternative Splicing : Fast-db (Paris)GSHG0031613
Alternative Splicing GalleryENSG00000147162
Gene ExpressionOGT [ NCBI-GEO ]   OGT [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15294 (SRS) O15294 (Uniprot)
NextProtO15294
With graphics : InterProO15294
Splice isoforms : SwissVarO15294(Swissvar)
Domaine pattern : Prosite (SRS)TPR (PS50005)    TPR_REGION (PS50293)   
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (SRS)TPR-1    TPR-contain_dom    TPR-like_helical    TPR_repeat   
Domains : Interpro (EBI)TPR-1    TPR-contain_dom    TPR-like_helical    TPR_repeat   
Related proteins : CluSTrO15294
Domain families : Pfam (SRS)TPR_1 (PF00515)   
Domain families : Pfam (Sanger)TPR_1 (PF00515)   
Domain families : Pfam (NCBI)pfam00515   
Domain families : Smart (EMBL)TPR (SM00028)  
DMDM8473
Blocks (Seattle)O15294
PDB (SRS)1W3B    3PE3    3PE4    3TAX   
PDB (PDBSum)1W3B    3PE3    3PE4    3TAX   
PDB (IMB)1W3B    3PE3    3PE4    3TAX   
PDB (RSDB)1W3B    3PE3    3PE4    3TAX   
Human Protein AtlasENSG00000147162
HPRD02222
IPIIPI00005780   IPI00219856   IPI00607723   IPI01008950   IPI00924555   IPI00924749   
Protein Interaction databases
DIP (DOE-UCLA)O15294
IntAct (EBI)O15294
FunCoupENSG00000147162
REACTOMEOGT
Protein Interaction Database8473
BioGRIDOGT
InParanoidO15294
Interologous Interaction database O15294
IntegromeDBOGT
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)OGT
SNP (GeneSNP Utah)OGT
SNP : HGBaseOGT
Genetic variants : HAPMAPOGT
Somatic Mutations in Cancer : COSMICOGT 
CONAN: Copy Number AnalysisOGT 
Mutations and Diseases : HGMDOGT
OMIM300255   
GENETests300255   
Disease Genetic AssociationOGT
Huge Navigator OGT [HugePedia]  OGT [HugeCancerGEM]
Genomic VariantsOGT  OGT [DGVbeta]
snp3D : Map Gene to Disease8473
General knowledge
Homologs : HomoloGeneOGT
Homology/Alignments : Family Browser (UCSC)OGT
Phylogenetic Trees/Animal Genes : TreeFamOGT
Catalytic activity : Enzyme2.4.1.255 [ Enzyme-Expasy ]   2.4.1.255 [ Enzyme-SRS ]   2.4.1.255 [ IntEnz-EBI ]   2.4.1.255 [ BRENDA ]   2.4.1.255 [ KEGG ]   
Chemical/Protein Interactions : CTD8473
Chemical/Pharm GKB GenePA31914
Clinical trialOGT
Cancer Resource (Charite)ENSG00000147162
Ontology : AmiGOhistone acetyltransferase complex  protein binding  phosphatidylinositol-3,4,5-trisphosphate binding  nucleus  nucleolus  mitochondrion  centrosome  cytosol  plasma membrane  regulation of glycolysis  protein O-linked glycosylation  apoptotic process  induction of apoptosis  signal transduction  response to nutrient  enzyme activator activity  acetylglucosaminyltransferase activity  protein N-acetylglucosaminyltransferase activity  positive regulation of granulocyte differentiation  response to insulin stimulus  regulation of Rac protein signal transduction  peptide binding  positive regulation of catalytic activity  histone H4-K5 acetylation  histone H4-K8 acetylation  histone H4-K16 acetylation  histone acetyltransferase activity (H4-K5 specific)  histone acetyltransferase activity (H4-K8 specific)  positive regulation of proteolysis  regulation of insulin receptor signaling pathway  histone acetyltransferase activity (H4-K16 specific)  phosphatidylinositol-mediated signaling  monosaccharide binding  positive regulation of histone H3-K4 methylation  protein homotrimerization  MLL5-L complex  cellular response to retinoic acid  
Ontology : EGO-EBIhistone acetyltransferase complex  protein binding  phosphatidylinositol-3,4,5-trisphosphate binding  nucleus  nucleolus  mitochondrion  centrosome  cytosol  plasma membrane  regulation of glycolysis  protein O-linked glycosylation  apoptotic process  induction of apoptosis  signal transduction  response to nutrient  enzyme activator activity  acetylglucosaminyltransferase activity  protein N-acetylglucosaminyltransferase activity  positive regulation of granulocyte differentiation  response to insulin stimulus  regulation of Rac protein signal transduction  peptide binding  positive regulation of catalytic activity  histone H4-K5 acetylation  histone H4-K8 acetylation  histone H4-K16 acetylation  histone acetyltransferase activity (H4-K5 specific)  histone acetyltransferase activity (H4-K8 specific)  positive regulation of proteolysis  regulation of insulin receptor signaling pathway  histone acetyltransferase activity (H4-K16 specific)  phosphatidylinositol-mediated signaling  monosaccharide binding  positive regulation of histone H3-K4 methylation  protein homotrimerization  MLL5-L complex  cellular response to retinoic acid  
Pathways : KEGGGlycan structures - biosynthesis 2Glycerolipid metabolismFructose and mannose metabolism
Other databases
Probes
Litterature
PubMed95 Pubmed reference(s) in Entrez
PubGeneOGT
iHOPOGT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:25:45 CEST 2013
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