Atlas of Genetics and Cytogenetics in Oncology and Haematology

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OLA1 (Obg like ATPase 1)

Identity

Alias (NCBI)DOC45
GBP45
GTBP9
GTPBP9
PTD004
HGNC (Hugo) OLA1
HGNC Alias symbPTD004
HGNC Previous nameGTPBP9
HGNC Previous nameGTP-binding protein 9 (putative)
LocusID (NCBI) 29789
Atlas_Id 51328
Location 2q31.1  [Link to chromosome band 2q31]
Location_base_pair Starts at 174072447 and ends at 174248532 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
OLA1 (2q31.1) / LRRFIP1 (2q37.3)OLA1 (2q31.1) / METTL8 (2q31.1)OLA1 (2q31.1) / ORMDL3 (17q12)
OSBPL10 (3p23) / OLA1 (2q31.1)SP3 (2q31.1) / OLA1 (2q31.1)TMEM173 (5q31.2) / OLA1 (2q31.1)
OLA1 2q31.1 / METTL8 2q31.1SP3 2q31.1 / OLA1 2q31.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)OLA1   28833
Cards
Entrez_Gene (NCBI)OLA1    Obg like ATPase 1
AliasesDOC45; GBP45; GTBP9; GTPBP9; 
PTD004
GeneCards (Weizmann)OLA1
Ensembl hg19 (Hinxton)ENSG00000138430 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138430 [Gene_View]  ENSG00000138430 [Sequence]  chr2:174072447-174248532 [Contig_View]  OLA1 [Vega]
ICGC DataPortalENSG00000138430
TCGA cBioPortalOLA1
AceView (NCBI)OLA1
Genatlas (Paris)OLA1
SOURCE (Princeton)OLA1
Genetics Home Reference (NIH)OLA1
Genomic and cartography
GoldenPath hg38 (UCSC)OLA1  -     chr2:174072447-174248532 -  2q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OLA1  -     2q31.1   [Description]    (hg19-Feb_2009)
GoldenPathOLA1 - 2q31.1 [CytoView hg19]  OLA1 - 2q31.1 [CytoView hg38]
ImmunoBaseENSG00000138430
genome Data Viewer NCBIOLA1 [Mapview hg19]  
OMIM611175   
Gene and transcription
Genbank (Entrez)AF078859 AF078868 AF116703 AF134478 AK027523
RefSeq transcript (Entrez)NM_001011708 NM_001328688 NM_013341
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OLA1
Alternative Splicing GalleryENSG00000138430
Gene ExpressionOLA1 [ NCBI-GEO ]   OLA1 [ EBI - ARRAY_EXPRESS ]   OLA1 [ SEEK ]   OLA1 [ MEM ]
Gene Expression Viewer (FireBrowse)OLA1 [ Firebrowse - Broad ]
GenevisibleExpression of OLA1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29789
GTEX Portal (Tissue expression)OLA1
Human Protein AtlasENSG00000138430-OLA1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NTK5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NTK5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NTK5
Splice isoforms : SwissVarQ9NTK5
PhosPhoSitePlusQ9NTK5
Domaine pattern : Prosite (Expaxy)G_OBG (PS51710)    TGS (PS51880)   
Domains : Interpro (EBI)ATPase_YchF/OLA1    Beta-grasp_dom_sf    G_OBG    GTP-bd    P-loop_NTPase    TGS    TGS-like    TGS-like_dom_sf    YchF_C    YchF_N   
Domain families : Pfam (Sanger)MMR_HSR1 (PF01926)    YchF-GTPase_C (PF06071)   
Domain families : Pfam (NCBI)pfam01926    pfam06071   
Conserved Domain (NCBI)OLA1
Blocks (Seattle)OLA1
PDB (RSDB)2OHF   
PDB Europe2OHF   
PDB (PDBSum)2OHF   
PDB (IMB)2OHF   
Structural Biology KnowledgeBase2OHF   
SCOP (Structural Classification of Proteins)2OHF   
CATH (Classification of proteins structures)2OHF   
SuperfamilyQ9NTK5
Human Protein Atlas [tissue]ENSG00000138430-OLA1 [tissue]
Peptide AtlasQ9NTK5
HPRD15194
IPIIPI00290416   IPI00216105   IPI00216106   IPI00916847   IPI00908669   IPI01014485   
Protein Interaction databases
DIP (DOE-UCLA)Q9NTK5
IntAct (EBI)Q9NTK5
BioGRIDOLA1
STRING (EMBL)OLA1
ZODIACOLA1
Ontologies - Pathways
QuickGOQ9NTK5
Ontology : AmiGOplatelet degranulation  protein binding  ATP binding  GTP binding  extracellular region  nucleolus  cytoplasm  cytoplasm  centrosome  cytosol  membrane  ATPase activity  ATPase activity  platelet alpha granule lumen  ribosome binding  ribosomal large subunit binding  cadherin binding  ATP metabolic process  metal ion binding  extracellular exosome  
Ontology : EGO-EBIplatelet degranulation  protein binding  ATP binding  GTP binding  extracellular region  nucleolus  cytoplasm  cytoplasm  centrosome  cytosol  membrane  ATPase activity  ATPase activity  platelet alpha granule lumen  ribosome binding  ribosomal large subunit binding  cadherin binding  ATP metabolic process  metal ion binding  extracellular exosome  
NDEx NetworkOLA1
Atlas of Cancer Signalling NetworkOLA1
Wikipedia pathwaysOLA1
Orthology - Evolution
OrthoDB29789
GeneTree (enSembl)ENSG00000138430
Phylogenetic Trees/Animal Genes : TreeFamOLA1
HOGENOMQ9NTK5
Homologs : HomoloGeneOLA1
Homology/Alignments : Family Browser (UCSC)OLA1
Gene fusions - Rearrangements
Fusion : MitelmanOLA1/METTL8 [2q31.1/2q31.1]  
Fusion : MitelmanOLA1/ORMDL3 [2q31.1/17q12]  
Fusion : MitelmanSP3/OLA1 [2q31.1/2q31.1]  
Fusion PortalOLA1 2q31.1 METTL8 2q31.1 BRCA
Fusion PortalSP3 2q31.1 OLA1 2q31.1 BRCA
Fusion : QuiverOLA1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOLA1 [hg38]
dbVarOLA1
ClinVarOLA1
MonarchOLA1
1000_GenomesOLA1 
Exome Variant ServerOLA1
GNOMAD BrowserENSG00000138430
Varsome BrowserOLA1
Genomic Variants (DGV)OLA1 [DGVbeta]
DECIPHEROLA1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOLA1 
Mutations
ICGC Data PortalOLA1 
TCGA Data PortalOLA1 
Broad Tumor PortalOLA1
OASIS PortalOLA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOLA1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DOLA1
Mutations and Diseases : HGMDOLA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OLA1
DgiDB (Drug Gene Interaction Database)OLA1
DoCM (Curated mutations)OLA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OLA1 (select a term)
intoGenOLA1
Cancer3DOLA1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611175   
Orphanet
DisGeNETOLA1
MedgenOLA1
Genetic Testing Registry OLA1
NextProtQ9NTK5 [Medical]
GENETestsOLA1
Target ValidationOLA1
Huge Navigator OLA1 [HugePedia]
ClinGenOLA1
Clinical trials, drugs, therapy
MyCancerGenomeOLA1
Protein Interactions : CTD
Pharm GKB GenePA162398388
PharosQ9NTK5
Clinical trialOLA1
Miscellaneous
canSAR (ICR)OLA1 (select the gene name)
HarmonizomeOLA1
DataMed IndexOLA1
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXOLA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:37:36 CET 2021
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