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OLA1 (Obg like ATPase 1)

Identity

Alias_namesGTPBP9
GTP-binding protein 9 (putative)
Alias_symbol (synonym)PTD004
Other aliasDOC45
GBP45
GTBP9
HGNC (Hugo) OLA1
LocusID (NCBI) 29789
Atlas_Id 51328
Location 2q31.1  [Link to chromosome band 2q31]
Location_base_pair Starts at 174072447 and ends at 174248670 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
OLA1 (2q31.1) / LRRFIP1 (2q37.3)OLA1 (2q31.1) / METTL8 (2q31.1)OLA1 (2q31.1) / ORMDL3 (17q12)
OSBPL10 (3p23) / OLA1 (2q31.1)SP3 (2q31.1) / OLA1 (2q31.1)TMEM173 (5q31.2) / OLA1 (2q31.1)
OLA1 2q31.1 / METTL8 2q31.1SP3 2q31.1 / OLA1 2q31.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OLA1   28833
Cards
Entrez_Gene (NCBI)OLA1  29789  Obg like ATPase 1
AliasesDOC45; GBP45; GTBP9; GTPBP9; 
PTD004
GeneCards (Weizmann)OLA1
Ensembl hg19 (Hinxton)ENSG00000138430 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138430 [Gene_View]  chr2:174072447-174248670 [Contig_View]  OLA1 [Vega]
ICGC DataPortalENSG00000138430
TCGA cBioPortalOLA1
AceView (NCBI)OLA1
Genatlas (Paris)OLA1
WikiGenes29789
SOURCE (Princeton)OLA1
Genetics Home Reference (NIH)OLA1
Genomic and cartography
GoldenPath hg38 (UCSC)OLA1  -     chr2:174072447-174248670 -  2q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OLA1  -     2q31.1   [Description]    (hg19-Feb_2009)
EnsemblOLA1 - 2q31.1 [CytoView hg19]  OLA1 - 2q31.1 [CytoView hg38]
Mapping of homologs : NCBIOLA1 [Mapview hg19]  OLA1 [Mapview hg38]
OMIM611175   
Gene and transcription
Genbank (Entrez)AF078859 AF078868 AF116703 AF134478 AK027523
RefSeq transcript (Entrez)NM_001011708 NM_001328688 NM_013341
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OLA1
Cluster EST : UnigeneHs.157351 [ NCBI ]
CGAP (NCI)Hs.157351
Alternative Splicing GalleryENSG00000138430
Gene ExpressionOLA1 [ NCBI-GEO ]   OLA1 [ EBI - ARRAY_EXPRESS ]   OLA1 [ SEEK ]   OLA1 [ MEM ]
Gene Expression Viewer (FireBrowse)OLA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29789
GTEX Portal (Tissue expression)OLA1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NTK5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NTK5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NTK5
Splice isoforms : SwissVarQ9NTK5
PhosPhoSitePlusQ9NTK5
Domaine pattern : Prosite (Expaxy)G_OBG (PS51710)   
Domains : Interpro (EBI)ATPase_YchF/OLA1    Beta-grasp_dom    DUF933    G_OBG    GTP_binding_domain    P-loop_NTPase    TGS-like    TGS-like_dom   
Domain families : Pfam (Sanger)MMR_HSR1 (PF01926)    YchF-GTPase_C (PF06071)   
Domain families : Pfam (NCBI)pfam01926    pfam06071   
Conserved Domain (NCBI)OLA1
DMDM Disease mutations29789
Blocks (Seattle)OLA1
PDB (SRS)2OHF   
PDB (PDBSum)2OHF   
PDB (IMB)2OHF   
PDB (RSDB)2OHF   
Structural Biology KnowledgeBase2OHF   
SCOP (Structural Classification of Proteins)2OHF   
CATH (Classification of proteins structures)2OHF   
SuperfamilyQ9NTK5
Human Protein AtlasENSG00000138430
Peptide AtlasQ9NTK5
HPRD15194
IPIIPI00290416   IPI00216105   IPI00216106   IPI00916847   IPI00908669   IPI01014485   
Protein Interaction databases
DIP (DOE-UCLA)Q9NTK5
IntAct (EBI)Q9NTK5
FunCoupENSG00000138430
BioGRIDOLA1
STRING (EMBL)OLA1
ZODIACOLA1
Ontologies - Pathways
QuickGOQ9NTK5
Ontology : AmiGOplatelet degranulation  protein binding  ATP binding  GTP binding  extracellular region  nucleolus  cytoplasm  cytoplasm  centrosome  cytosol  membrane  ATPase activity  platelet alpha granule lumen  cadherin binding  ATP metabolic process  metal ion binding  extracellular exosome  
Ontology : EGO-EBIplatelet degranulation  protein binding  ATP binding  GTP binding  extracellular region  nucleolus  cytoplasm  cytoplasm  centrosome  cytosol  membrane  ATPase activity  platelet alpha granule lumen  cadherin binding  ATP metabolic process  metal ion binding  extracellular exosome  
NDEx NetworkOLA1
Atlas of Cancer Signalling NetworkOLA1
Wikipedia pathwaysOLA1
Orthology - Evolution
OrthoDB29789
GeneTree (enSembl)ENSG00000138430
Phylogenetic Trees/Animal Genes : TreeFamOLA1
HOVERGENQ9NTK5
HOGENOMQ9NTK5
Homologs : HomoloGeneOLA1
Homology/Alignments : Family Browser (UCSC)OLA1
Gene fusions - Rearrangements
Fusion : MitelmanOLA1/METTL8 [2q31.1/2q31.1]  
Fusion : MitelmanOLA1/ORMDL3 [2q31.1/17q12]  [t(2;17)(q31;q12)]  
Fusion : MitelmanSP3/OLA1 [2q31.1/2q31.1]  [t(2;2)(q31;q31)]  
Fusion: TCGAOLA1 2q31.1 METTL8 2q31.1 BRCA
Fusion: TCGASP3 2q31.1 OLA1 2q31.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOLA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OLA1
dbVarOLA1
ClinVarOLA1
1000_GenomesOLA1 
Exome Variant ServerOLA1
ExAC (Exome Aggregation Consortium)OLA1 (select the gene name)
Genetic variants : HAPMAP29789
Genomic Variants (DGV)OLA1 [DGVbeta]
DECIPHEROLA1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOLA1 
Mutations
ICGC Data PortalOLA1 
TCGA Data PortalOLA1 
Broad Tumor PortalOLA1
OASIS PortalOLA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOLA1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOLA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OLA1
DgiDB (Drug Gene Interaction Database)OLA1
DoCM (Curated mutations)OLA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OLA1 (select a term)
intoGenOLA1
Cancer3DOLA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611175   
Orphanet
MedgenOLA1
Genetic Testing Registry OLA1
NextProtQ9NTK5 [Medical]
TSGene29789
GENETestsOLA1
Target ValidationOLA1
Huge Navigator OLA1 [HugePedia]
snp3D : Map Gene to Disease29789
BioCentury BCIQOLA1
ClinGenOLA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29789
Chemical/Pharm GKB GenePA162398388
Clinical trialOLA1
Miscellaneous
canSAR (ICR)OLA1 (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOLA1
EVEXOLA1
GoPubMedOLA1
iHOPOLA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Sep 18 14:02:16 CEST 2017

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