OMD (osteomodulin)

2007-03-01 Affiliation

Identity

HGNC

OMD

LOCATION

9q22.31

LOCUSID

4958

ALIAS

OSAD,SLRR2C

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 4958
MIM: 618926
HGNC: 8134
Ensembl: ENSG00000127083

Variants:

dbSNP: 4958
ClinVar: 4958
TCGA: ENSG00000127083
COSMIC: OMD

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000127083	ENST00000375550	Q99983

Expression (GTEx)

100

150

200

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Disease	REACTOME	R-HSA-1643685
Diseases of glycosylation	REACTOME	R-HSA-3781865
Diseases associated with glycosaminoglycan metabolism	REACTOME	R-HSA-3560782
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)	REACTOME	R-HSA-3656244
Defective CHST6 causes MCDC1	REACTOME	R-HSA-3656225
Metabolism	REACTOME	R-HSA-1430728
Metabolism of carbohydrates	REACTOME	R-HSA-71387
Glycosaminoglycan metabolism	REACTOME	R-HSA-1630316
Keratan sulfate/keratin metabolism	REACTOME	R-HSA-1638074
Keratan sulfate biosynthesis	REACTOME	R-HSA-2022854
Keratan sulfate degradation	REACTOME	R-HSA-2022857
Defective ST3GAL3 causes MCT12 and EIEE15	REACTOME	R-HSA-3656243

References

Pubmed ID	Year	Title	Citations
19700767	2009	The tyrosine sulfate-rich domains of the LRR proteins fibromodulin and osteoadherin bind motifs of basic clusters in a variety of heparin-binding proteins, including bioactive factors.	18
26003732	2015	Osteomodulin regulates diameter and alters shape of collagen fibrils.	15
25371314	2015	Distinct dysregulation of the small leucine-rich repeat protein family in osteoarthritic acetabular labrum compared to articular cartilage.	5
12489179	2002	TGF beta 1 signaling and stimulation of osteoadherin in human odontoblasts in vitro.	0

Citation

Dessen P

OMD (osteomodulin)

Atlas Genet Cytogenet Oncol Haematol. 2007-03-01

Online version: http://atlasgeneticsoncology.org/gene/42962/omd