Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ONECUT2 (one cut homeobox 2)

Identity

Alias_namesone cut domain
Alias_symbol (synonym)OC-2
Other aliasOC2
HGNC (Hugo) ONECUT2
LocusID (NCBI) 9480
Atlas_Id 50603
Location 18q21.31  [Link to chromosome band 18q21]
Location_base_pair Starts at 57435685 and ends at 57491298 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ONECUT2   8139
Cards
Entrez_Gene (NCBI)ONECUT2  9480  one cut homeobox 2
AliasesOC-2; OC2
GeneCards (Weizmann)ONECUT2
Ensembl hg19 (Hinxton)ENSG00000119547 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000119547 [Gene_View]  chr18:57435685-57491298 [Contig_View]  ONECUT2 [Vega]
ICGC DataPortalENSG00000119547
TCGA cBioPortalONECUT2
AceView (NCBI)ONECUT2
Genatlas (Paris)ONECUT2
WikiGenes9480
SOURCE (Princeton)ONECUT2
Genetics Home Reference (NIH)ONECUT2
Genomic and cartography
GoldenPath hg38 (UCSC)ONECUT2  -     chr18:57435685-57491298 +  18q21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ONECUT2  -     18q21.31   [Description]    (hg19-Feb_2009)
EnsemblONECUT2 - 18q21.31 [CytoView hg19]  ONECUT2 - 18q21.31 [CytoView hg38]
Mapping of homologs : NCBIONECUT2 [Mapview hg19]  ONECUT2 [Mapview hg38]
OMIM604894   
Gene and transcription
Genbank (Entrez)AK021717 AK124558 BC013134 BC108925 BC108926
RefSeq transcript (Entrez)NM_004852
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ONECUT2
Cluster EST : UnigeneHs.194725 [ NCBI ]
CGAP (NCI)Hs.194725
Alternative Splicing GalleryENSG00000119547
Gene ExpressionONECUT2 [ NCBI-GEO ]   ONECUT2 [ EBI - ARRAY_EXPRESS ]   ONECUT2 [ SEEK ]   ONECUT2 [ MEM ]
Gene Expression Viewer (FireBrowse)ONECUT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9480
GTEX Portal (Tissue expression)ONECUT2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95948   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95948  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95948
Splice isoforms : SwissVarO95948
PhosPhoSitePlusO95948
Domaine pattern : Prosite (Expaxy)CUT (PS51042)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)CUT_dom    Homeobox-like    Homeobox_dom    Lambda_DNA-bd_dom   
Domain families : Pfam (Sanger)CUT (PF02376)    Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam02376    pfam00046   
Domain families : Smart (EMBL)CUT (SM01109)  HOX (SM00389)  
Conserved Domain (NCBI)ONECUT2
DMDM Disease mutations9480
Blocks (Seattle)ONECUT2
SuperfamilyO95948
Human Protein AtlasENSG00000119547
Peptide AtlasO95948
HPRD05354
IPIIPI00001413   IPI00946001   
Protein Interaction databases
DIP (DOE-UCLA)O95948
IntAct (EBI)O95948
FunCoupENSG00000119547
BioGRIDONECUT2
STRING (EMBL)ONECUT2
ZODIACONECUT2
Ontologies - Pathways
QuickGOO95948
Ontology : AmiGORNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  liver development  regulation of cell-matrix adhesion  epithelial cell development  nucleus  nucleoplasm  transcription from RNA polymerase II promoter  animal organ morphogenesis  actin cytoskeleton  cell differentiation  positive regulation of cell migration  negative regulation of transforming growth factor beta receptor signaling pathway  endocrine pancreas development  cell fate commitment  positive regulation of transcription from RNA polymerase II promoter  peripheral nervous system neuron development  cilium assembly  
Ontology : EGO-EBIRNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  liver development  regulation of cell-matrix adhesion  epithelial cell development  nucleus  nucleoplasm  transcription from RNA polymerase II promoter  animal organ morphogenesis  actin cytoskeleton  cell differentiation  positive regulation of cell migration  negative regulation of transforming growth factor beta receptor signaling pathway  endocrine pancreas development  cell fate commitment  positive regulation of transcription from RNA polymerase II promoter  peripheral nervous system neuron development  cilium assembly  
NDEx NetworkONECUT2
Atlas of Cancer Signalling NetworkONECUT2
Wikipedia pathwaysONECUT2
Orthology - Evolution
OrthoDB9480
GeneTree (enSembl)ENSG00000119547
Phylogenetic Trees/Animal Genes : TreeFamONECUT2
HOVERGENO95948
HOGENOMO95948
Homologs : HomoloGeneONECUT2
Homology/Alignments : Family Browser (UCSC)ONECUT2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerONECUT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ONECUT2
dbVarONECUT2
ClinVarONECUT2
1000_GenomesONECUT2 
Exome Variant ServerONECUT2
ExAC (Exome Aggregation Consortium)ONECUT2 (select the gene name)
Genetic variants : HAPMAP9480
Genomic Variants (DGV)ONECUT2 [DGVbeta]
DECIPHERONECUT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisONECUT2 
Mutations
ICGC Data PortalONECUT2 
TCGA Data PortalONECUT2 
Broad Tumor PortalONECUT2
OASIS PortalONECUT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICONECUT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDONECUT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ONECUT2
DgiDB (Drug Gene Interaction Database)ONECUT2
DoCM (Curated mutations)ONECUT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ONECUT2 (select a term)
intoGenONECUT2
Cancer3DONECUT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604894   
Orphanet
MedgenONECUT2
Genetic Testing Registry ONECUT2
NextProtO95948 [Medical]
TSGene9480
GENETestsONECUT2
Target ValidationONECUT2
Huge Navigator ONECUT2 [HugePedia]
snp3D : Map Gene to Disease9480
BioCentury BCIQONECUT2
ClinGenONECUT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9480
Chemical/Pharm GKB GenePA31925
Clinical trialONECUT2
Miscellaneous
canSAR (ICR)ONECUT2 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineONECUT2
EVEXONECUT2
GoPubMedONECUT2
iHOPONECUT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:02:17 CEST 2017

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