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ONECUT3 (one cut homeobox 3)

Identity

Alias_namesone cut domain, family member 3
Other aliasOC3
HGNC (Hugo) ONECUT3
LocusID (NCBI) 390874
Atlas_Id 71120
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 1753663 and ends at 1775445 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DOT1L (19p13.3) / ONECUT3 (19p13.3)HK2 (2p12) / ONECUT3 (19p13.3)DOT1L ONECUT3
HK2 ONECUT3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ONECUT3   13399
Cards
Entrez_Gene (NCBI)ONECUT3  390874  one cut homeobox 3
AliasesOC3
GeneCards (Weizmann)ONECUT3
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr19:1753663-1775445 [Contig_View]  ONECUT3 [Vega]
TCGA cBioPortalONECUT3
AceView (NCBI)ONECUT3
Genatlas (Paris)ONECUT3
WikiGenes390874
SOURCE (Princeton)ONECUT3
Genetics Home Reference (NIH)ONECUT3
Genomic and cartography
GoldenPath hg38 (UCSC)ONECUT3  -     chr19:1753663-1775445 +  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ONECUT3  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblONECUT3 - 19p13.3 [CytoView hg19]  ONECUT3 - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIONECUT3 [Mapview hg19]  ONECUT3 [Mapview hg38]
OMIM611294   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001080488
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ONECUT3
Cluster EST : UnigeneHs.654347 [ NCBI ]
CGAP (NCI)Hs.654347
Gene ExpressionONECUT3 [ NCBI-GEO ]   ONECUT3 [ EBI - ARRAY_EXPRESS ]   ONECUT3 [ SEEK ]   ONECUT3 [ MEM ]
Gene Expression Viewer (FireBrowse)ONECUT3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)390874
GTEX Portal (Tissue expression)ONECUT3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60422   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60422  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60422
Splice isoforms : SwissVarO60422
PhosPhoSitePlusO60422
Domaine pattern : Prosite (Expaxy)CUT (PS51042)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)CUT_dom    Homeobox-like    Homeobox_dom    Lambda_DNA-bd_dom   
Domain families : Pfam (Sanger)CUT (PF02376)    Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam02376    pfam00046   
Domain families : Smart (EMBL)CUT (SM01109)  HOX (SM00389)  
Conserved Domain (NCBI)ONECUT3
DMDM Disease mutations390874
Blocks (Seattle)ONECUT3
SuperfamilyO60422
Peptide AtlasO60422
IPIIPI00556491   
Protein Interaction databases
DIP (DOE-UCLA)O60422
IntAct (EBI)O60422
BioGRIDONECUT3
STRING (EMBL)ONECUT3
ZODIACONECUT3
Ontologies - Pathways
QuickGOO60422
Ontology : AmiGORNA polymerase II regulatory region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  DNA binding  nucleus  transcription factor complex  transcription from RNA polymerase II promoter  cell differentiation  positive regulation of transcription from RNA polymerase II promoter  system development  
Ontology : EGO-EBIRNA polymerase II regulatory region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  DNA binding  nucleus  transcription factor complex  transcription from RNA polymerase II promoter  cell differentiation  positive regulation of transcription from RNA polymerase II promoter  system development  
NDEx NetworkONECUT3
Atlas of Cancer Signalling NetworkONECUT3
Wikipedia pathwaysONECUT3
Orthology - Evolution
OrthoDB390874
Phylogenetic Trees/Animal Genes : TreeFamONECUT3
HOVERGENO60422
HOGENOMO60422
Homologs : HomoloGeneONECUT3
Homology/Alignments : Family Browser (UCSC)ONECUT3
Gene fusions - Rearrangements
Fusion: TCGADOT1L ONECUT3
Fusion: TCGAHK2 ONECUT3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerONECUT3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ONECUT3
dbVarONECUT3
ClinVarONECUT3
1000_GenomesONECUT3 
Exome Variant ServerONECUT3
ExAC (Exome Aggregation Consortium)ONECUT3 (select the gene name)
Genetic variants : HAPMAP390874
Genomic Variants (DGV)ONECUT3 [DGVbeta]
DECIPHERONECUT3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisONECUT3 
Mutations
ICGC Data PortalONECUT3 
TCGA Data PortalONECUT3 
Broad Tumor PortalONECUT3
OASIS PortalONECUT3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICONECUT3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDONECUT3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ONECUT3
DgiDB (Drug Gene Interaction Database)ONECUT3
DoCM (Curated mutations)ONECUT3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ONECUT3 (select a term)
intoGenONECUT3
Cancer3DONECUT3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611294   
Orphanet
MedgenONECUT3
Genetic Testing Registry ONECUT3
NextProtO60422 [Medical]
TSGene390874
GENETestsONECUT3
Target ValidationONECUT3
Huge Navigator ONECUT3 [HugePedia]
snp3D : Map Gene to Disease390874
BioCentury BCIQONECUT3
ClinGenONECUT3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD390874
Chemical/Pharm GKB GenePA31926
Clinical trialONECUT3
Miscellaneous
canSAR (ICR)ONECUT3 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineONECUT3
EVEXONECUT3
GoPubMedONECUT3
iHOPONECUT3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:32:39 CEST 2017

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