Atlas of Genetics and Cytogenetics in Oncology and Haematology


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OPN4 (opsin 4)

Identity

Alias_namesopsin 4 (melanopsin)
Alias_symbol (synonym)MOP
melanopsin
Other alias
HGNC (Hugo) OPN4
LocusID (NCBI) 94233
Atlas_Id 71135
Location 10q23.2  [Link to chromosome band 10q23]
Location_base_pair Starts at 86654557 and ends at 86666459 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OPN4   14449
Cards
Entrez_Gene (NCBI)OPN4  94233  opsin 4
AliasesMOP
GeneCards (Weizmann)OPN4
Ensembl hg19 (Hinxton)ENSG00000122375 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000122375 [Gene_View]  chr10:86654557-86666459 [Contig_View]  OPN4 [Vega]
ICGC DataPortalENSG00000122375
TCGA cBioPortalOPN4
AceView (NCBI)OPN4
Genatlas (Paris)OPN4
WikiGenes94233
SOURCE (Princeton)OPN4
Genetics Home Reference (NIH)OPN4
Genomic and cartography
GoldenPath hg38 (UCSC)OPN4  -     chr10:86654557-86666459 +  10q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OPN4  -     10q23.2   [Description]    (hg19-Feb_2009)
EnsemblOPN4 - 10q23.2 [CytoView hg19]  OPN4 - 10q23.2 [CytoView hg38]
Mapping of homologs : NCBIOPN4 [Mapview hg19]  OPN4 [Mapview hg38]
OMIM606665   
Gene and transcription
Genbank (Entrez)AK310520 BC029291 BC113558 BC143688 BM672338
RefSeq transcript (Entrez)NM_001030015 NM_033282
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OPN4
Cluster EST : UnigeneHs.283922 [ NCBI ]
CGAP (NCI)Hs.283922
Alternative Splicing GalleryENSG00000122375
Gene ExpressionOPN4 [ NCBI-GEO ]   OPN4 [ EBI - ARRAY_EXPRESS ]   OPN4 [ SEEK ]   OPN4 [ MEM ]
Gene Expression Viewer (FireBrowse)OPN4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)94233
GTEX Portal (Tissue expression)OPN4
Human Protein AtlasENSG00000122375-OPN4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UHM6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UHM6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UHM6
Splice isoforms : SwissVarQ9UHM6
PhosPhoSitePlusQ9UHM6
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)    OPSIN (PS00238)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Opsin    Retinal_BS   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Domain families : Smart (EMBL)7TM_GPCR_Srsx (SM01381)  
Conserved Domain (NCBI)OPN4
DMDM Disease mutations94233
Blocks (Seattle)OPN4
SuperfamilyQ9UHM6
Human Protein Atlas [tissue]ENSG00000122375-OPN4 [tissue]
Peptide AtlasQ9UHM6
HPRD05977
IPIIPI00005930   IPI00646790   
Protein Interaction databases
DIP (DOE-UCLA)Q9UHM6
IntAct (EBI)Q9UHM6
FunCoupENSG00000122375
BioGRIDOPN4
STRING (EMBL)OPN4
ZODIACOPN4
Ontologies - Pathways
QuickGOQ9UHM6
Ontology : AmiGO11-cis retinal binding  plasma membrane  visual perception  phototransduction  G-protein coupled photoreceptor activity  integral component of membrane  rhodopsin mediated signaling pathway  protein-chromophore linkage  regulation of circadian rhythm  rhythmic process  
Ontology : EGO-EBI11-cis retinal binding  plasma membrane  visual perception  phototransduction  G-protein coupled photoreceptor activity  integral component of membrane  rhodopsin mediated signaling pathway  protein-chromophore linkage  regulation of circadian rhythm  rhythmic process  
NDEx NetworkOPN4
Atlas of Cancer Signalling NetworkOPN4
Wikipedia pathwaysOPN4
Orthology - Evolution
OrthoDB94233
GeneTree (enSembl)ENSG00000122375
Phylogenetic Trees/Animal Genes : TreeFamOPN4
HOVERGENQ9UHM6
HOGENOMQ9UHM6
Homologs : HomoloGeneOPN4
Homology/Alignments : Family Browser (UCSC)OPN4
Gene fusions - Rearrangements
Tumor Fusion PortalOPN4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOPN4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OPN4
dbVarOPN4
ClinVarOPN4
1000_GenomesOPN4 
Exome Variant ServerOPN4
ExAC (Exome Aggregation Consortium)ENSG00000122375
GNOMAD BrowserENSG00000122375
Genetic variants : HAPMAP94233
Genomic Variants (DGV)OPN4 [DGVbeta]
DECIPHEROPN4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOPN4 
Mutations
ICGC Data PortalOPN4 
TCGA Data PortalOPN4 
Broad Tumor PortalOPN4
OASIS PortalOPN4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOPN4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOPN4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OPN4
DgiDB (Drug Gene Interaction Database)OPN4
DoCM (Curated mutations)OPN4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OPN4 (select a term)
intoGenOPN4
Cancer3DOPN4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606665   
Orphanet
DisGeNETOPN4
MedgenOPN4
Genetic Testing Registry OPN4
NextProtQ9UHM6 [Medical]
TSGene94233
GENETestsOPN4
Target ValidationOPN4
Huge Navigator OPN4 [HugePedia]
snp3D : Map Gene to Disease94233
BioCentury BCIQOPN4
ClinGenOPN4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD94233
Chemical/Pharm GKB GenePA31940
Clinical trialOPN4
Miscellaneous
canSAR (ICR)OPN4 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOPN4
EVEXOPN4
GoPubMedOPN4
iHOPOPN4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:22:19 CET 2017

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